Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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$250K - $300K *

Champion the development of groundbreaking AI systems by driving research, orchestrating agent workflows, and enhancing reliability of autonomous operations, while collaborating with cross-functional...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$81K - $107K *

Accelerate progress at the forefront of genomic medicine through hands-on laboratory research and innovative bio-assay development, collaborating with a dynamic team to enhance novel technologies and...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$185K - $225K *

Pioneer innovative solutions in data science and AI, collaborating closely with product teams. Drive customer-focused projects, lead marketing efforts, and serve as a technical expert to ensure delive...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$155K - $179K *

Shape the future of digital energy solutions by leading user experience research. Collaborate with cross-functional teams to identify user needs and inform design strategies that enhance our sustainab...

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$120K - $175K *

Provide scientific leadership for in vivo pharmacology studies in inflammation and autoimmunity, coordinating cross-functional efforts and external collaborations to support drug development and ensur...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Join us to lead innovative AI and data solutions, supervise teams, and drive strategic implementation across projects. Utilize your expertise in AI/ML to enhance operational capabilities while mentori...

2 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$106K - $120K *

Oversee and enhance multi-site manufacturing operations, ensuring compliance and efficiency. Collaborate with executive teams to drive operational excellence and deliver high-quality products in regul...

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$103K - $118K *

Transform the landscape of cancer research by driving target identification and validation as an integral member of a dynamic, multidisciplinary team focused on novel therapeutics and innovative drug...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Architect and validate analytical testing methodologies to enhance project outcomes in a collaborative lab environment, ensuring compliance with GMP regulations and driving improvements in product qua...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $230K *

Join a committed team driving quality excellence in a global nonprofit. Lead and innovate an extensive Quality organization ensuring compliance and integrity across all operations while enhancing work...

1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$200K - $230K *

Drive enterprise-wide quality as a senior leader, overseeing compliance and quality assurance across bioproduction and operations, while enhancing team performance and integration in a regulated envir...

1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in developing next-generation semiconductor hardware solutions. Oversee a dynamic engineering team throughout the product lifecycle, driving innovation, quality, and performance in a f...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$82K - $108K *

Drive impactful research by optimizing in vitro assays and advancing molecular characterization, focusing on innovative methodologies to support diverse scientific projects across biology and chemistr...

Hamilton, ONIn-Person

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$82K - $108K *

Lead the charge in advancing radio conjugate programs through assay development and data analysis. Collaborate across disciplines to execute in vitro experiments and provide critical support for targe...

Hamilton, ONIn-Person

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$193K - $338K *

Optimize clinical trial strategies in gene editing therapies targeting cardiovascular disease. Collaborate with cross-functional teams and lead high-impact clinical research efforts to ensure patient...

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$125K - $135K *

Join a team that's driving global clinical trial success, managing multifaceted projects. Leverage your expertise in the pharmaceutical landscape to guide cross-functional teams while maintaining stro...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Unlock potential by leading integrated program teams to drive laser development initiatives from inception to completion, ensuring alignment across engineering, operations, and customer relations to m...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$100K - $126K *

Join a dynamic Pharmacology team to innovate and execute cell-based and biochemical assays that propel drug discovery and development while collaborating cross-functionally to enhance scientific outco...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Engineer advanced inventory intelligence by leading optimization models and AI solutions. Collaborate cross-functionally to enhance data-driven decision-making for enterprise maintenance operations wh...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$192K - $272K *

Champion cutting-edge data infrastructure development, guiding technical architecture and mentoring engineers to enhance data platform capabilities for scientific and ML workflows while ensuring relia...

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$192K - $272K *

Lead the architectural evolution of core data infrastructure, driving the design of ingestion frameworks and orchestration systems. Collaborate across teams to ensure durable platform capabilities for...

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $120K *

Join a team that's committed to innovation and sustainability. Lead technical projects from inception to completion, ensuring compliance and efficiency while mentoring and driving improvement across o...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $120K *

Partner with us to bridge metallurgy and geophysics, driving innovation through solution design and field execution in hydrometallurgy. Collaborate closely with diverse teams and enhance operations in...

5 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$145K - $160K *

Manage daily operations of ESL/Reliability labs, ensuring project execution, resource allocation, and operational excellence while leading engineering teams and driving customer satisfaction across te...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$131K - $153K *

Join a dynamic team to advance analytical capabilities in diverse food and beverage sectors. Bring your expertise in advanced methodologies and project ownership to shape nutrition innovation from R&D...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.