Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal AI Researcher (Agentic Systems & AI Infrastructure)
$250K - $300K *
Champion the development of groundbreaking AI systems by driving research, orchestrating agent workflows, and enhancing reliability of autonomous operations, while collaborating with cross-functional...
2 weeks ago
Senior Research Associate, Translational
$81K - $107K *
Accelerate progress at the forefront of genomic medicine through hands-on laboratory research and innovative bio-assay development, collaborating with a dynamic team to enhance novel technologies and...
4 days ago
Principal Product Manager, Data Science
$185K - $225K *
Pioneer innovative solutions in data science and AI, collaborating closely with product teams. Drive customer-focused projects, lead marketing efforts, and serve as a technical expert to ensure delive...
2 weeks ago
Principal Experience Researcher
$155K - $179K *
Shape the future of digital energy solutions by leading user experience research. Collaborate with cross-functional teams to identify user needs and inform design strategies that enhance our sustainab...
1 week ago
Scientist, In Vivo Pharmacology
$120K - $175K *
Provide scientific leadership for in vivo pharmacology studies in inflammation and autoimmunity, coordinating cross-functional efforts and external collaborations to support drug development and ensur...
1 week ago
Lead Technical Engineer, Advanced Concepts
$130K - $160K *
Join us to lead innovative AI and data solutions, supervise teams, and drive strategic implementation across projects. Utilize your expertise in AI/ML to enhance operational capabilities while mentori...
2 days ago
Manufacturing Director (Biotech)
$106K - $120K *
Oversee and enhance multi-site manufacturing operations, ensuring compliance and efficiency. Collaborate with executive teams to drive operational excellence and deliver high-quality products in regul...
4 days ago
$103K - $118K *
Transform the landscape of cancer research by driving target identification and validation as an integral member of a dynamic, multidisciplinary team focused on novel therapeutics and innovative drug...
3 days ago
Analytical Development, Sr. Scientist III
$90K - $120K *
Architect and validate analytical testing methodologies to enhance project outcomes in a collaborative lab environment, ensuring compliance with GMP regulations and driving improvements in product qua...
4 days ago
$200K - $230K *
Join a committed team driving quality excellence in a global nonprofit. Lead and innovate an extensive Quality organization ensuring compliance and integrity across all operations while enhancing work...
1 week ago
$200K - $230K *
Drive enterprise-wide quality as a senior leader, overseeing compliance and quality assurance across bioproduction and operations, while enhancing team performance and integration in a regulated envir...
1 week ago
Manager, Mechanical Engineering R&D
$120K - $150K *
Lead the charge in developing next-generation semiconductor hardware solutions. Oversee a dynamic engineering team throughout the product lifecycle, driving innovation, quality, and performance in a f...
3 weeks ago
Scientist - RC Discovery Biology
$82K - $108K *
Drive impactful research by optimizing in vitro assays and advancing molecular characterization, focusing on innovative methodologies to support diverse scientific projects across biology and chemistr...
6 days ago
Scientist - RC Discovery Biology
$82K - $108K *
Lead the charge in advancing radio conjugate programs through assay development and data analysis. Collaborate across disciplines to execute in vitro experiments and provide critical support for targe...
6 days ago
Director - Clinical Research Scientist
$193K - $338K *
Optimize clinical trial strategies in gene editing therapies targeting cardiovascular disease. Collaborate with cross-functional teams and lead high-impact clinical research efforts to ensure patient...
4 days ago
Senior Project Manager, Clinical Trials
$125K - $135K *
Join a team that's driving global clinical trial success, managing multifaceted projects. Leverage your expertise in the pharmaceutical landscape to guide cross-functional teams while maintaining stro...
3 weeks ago
$120K - $150K *
Unlock potential by leading integrated program teams to drive laser development initiatives from inception to completion, ensuring alignment across engineering, operations, and customer relations to m...
2 weeks ago
Scientist I, In Vitro Pharmacology
$100K - $126K *
Join a dynamic Pharmacology team to innovate and execute cell-based and biochemical assays that propel drug discovery and development while collaborating cross-functionally to enhance scientific outco...
5 days ago
Senior Applied Scientist, Parts Intelligence & Inventory Optimization
$120K - $150K *
Engineer advanced inventory intelligence by leading optimization models and AI solutions. Collaborate cross-functionally to enhance data-driven decision-making for enterprise maintenance operations wh...
5 days ago
$192K - $272K *
Champion cutting-edge data infrastructure development, guiding technical architecture and mentoring engineers to enhance data platform capabilities for scientific and ML workflows while ensuring relia...
5 days ago
$192K - $272K *
Lead the architectural evolution of core data infrastructure, driving the design of ingestion frameworks and orchestration systems. Collaborate across teams to ensure durable platform capabilities for...
5 days ago
Senior Engineering Project Manager
$90K - $120K *
Join a team that's committed to innovation and sustainability. Lead technical projects from inception to completion, ensuring compliance and efficiency while mentoring and driving improvement across o...
3 weeks ago
$90K - $120K *
Partner with us to bridge metallurgy and geophysics, driving innovation through solution design and field execution in hydrometallurgy. Collaborate closely with diverse teams and enhance operations in...
5 days ago
Environmental Simulation Lab & Reliability Department Manager / SME
$145K - $160K *
Manage daily operations of ESL/Reliability labs, ensuring project execution, resource allocation, and operational excellence while leading engineering teams and driving customer satisfaction across te...
2 weeks ago
Senior Manager, Analytical Chemistry Scientist
$131K - $153K *
Join a dynamic team to advance analytical capabilities in diverse food and beverage sectors. Bring your expertise in advanced methodologies and project ownership to shape nutrition innovation from R&D...
1 week ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.