Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$115K - $130K *

Lead product strategy and development in the life sciences sector. Manage global product lines, analyze market opportunities, and drive growth strategies. Collaborate with cross-functional teams to en...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the generation and optimization of recombinant protein biotherapeutics, managing a dedicated team of scientists through all phases from DNA design to protein purification, ensuring delivery of hi...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$166K - $266K *

Drive innovative cancer research by developing assays and conducting experiments to inform drug development. Collaborate cross-functionally, translate preclinical data, and mentor junior scientists in...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Shape the future of operational excellence by leading cross-functional teams to drive continuous improvement through data analysis, Lean, and Six Sigma methodologies, enhancing efficiency and producti...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Drive a culture of continuous improvement, leveraging data analysis and Lean Six Sigma methods to enhance manufacturing processes globally while guiding cross-functional teams and driving organization...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform oligonucleotide synthesis by developing innovative workflows, optimizing processes, and applying your chemistry expertise to enhance efficiency and product quality in this hands-on research...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Lead the charge in advancing innovative RNA therapeutics through in vivo efficacy testing and collaborative research efforts, driving scientific discovery in a fast-paced biotech environment...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$158K - $187K *

Architect innovative health sensing algorithms to advance Oura's wearable technology. Collaborate with cross-functional teams to develop features, conduct research, and optimize products, impacting he...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$72K - $94K *

Join a team that's advancing R&D in industrial minerals by executing experimental plans, analyzing data, and developing testing procedures. Contribute to innovative product applications in a supportiv...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Join a team that's focused on delivering innovative products by effectively managing projects from concept through execution. You'll ensure successful outcomes while leading cross-functional teams to...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$145K - $180K *

Empower innovation by leading the product strategy of a virtual science companion. Collaborate with scientists to enhance laboratory workflows across various sectors, ensuring quality and efficiency i...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape and oversee the execution of clinical studies in early and late-stage development, ensuring regulatory compliance and scientific integrity while collaborating with cross-functional teams to driv...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Advance the field of research by applying simple yet scalable methods on large datasets, optimizing for efficiency and effectiveness in diverse multimodal applications. Collaborate closely with expert...

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$76K - $88K *

Collaborate in the development and management of immunoassay processes by designing experiments and ensuring quality control, while supporting process transfers and validations in a GMP environment to...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $150K *

Unlock potential by driving innovation in magnetic resonance imaging systems and applications. Collaborate with interdisciplinary teams to develop advanced MRI solutions, enhance imaging capabilities...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$174K - $248K *

Advance your career by leading innovative research in Earth observation and AI. Drive the scientific roadmap for data integration and develop scalable models, transforming vast data streams into actio...

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$125K - $150K *

Join a team that's revolutionizing high-temperature materials by synthesizing innovative compounds and enhancing manufacturing processes. Collaborate across disciplines to drive advancements in compos...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$118K - $145K *

Lead the charge in designing and optimizing transient transfection workflows for antibody and protein production, while driving innovation through analytical studies and high-throughput automation in...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$66K - $154K *

Shape the future of pharmaceutical manufacturing as Lab Manager, ensuring operational readiness and compliance while collaborating across diverse teams to drive laboratory excellence and efficiency at...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$66K - $154K *

Lead daily operations and compliance in synthetic laboratories, ensuring readiness for manufacturing and development activities while fostering collaboration across functional teams and promoting a cu...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$144K - $216K *

Lead the design and implementation of advanced agentic AI systems in life sciences, focusing on clinical applications. Collaborate with cross-functional teams to drive innovative solutions that enhanc...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Transform existing product lines by leading scientific innovations that enhance efficacy, quality, and consumer satisfaction. Collaborate across teams to drive evidence-based improvements for dietary...

3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$254K - $361K *

Transform complex therapeutic programs by leading cross-functional teams to achieve strategic goals. Drive the development and execution of project plans while navigating complexities within drug disc...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a dynamic team to optimize and control microelectronic manufacturing processes, focusing on continuous improvement and technical support for silicon and III-V device fabrication...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$160K - $180K *

Empower your career with a key role leading the management of defense acquisition programs, ensuring timely delivery, performance, and budget goals while analyzing effectiveness and coordinating high...

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.