Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$80K - $95K *
Develop and validate analytical methods while supporting bioanalytical studies. Provide technical expertise to junior staff and ensure compliance with GLP regulations while troubleshooting equipment a...
3 weeks ago
Scientist - Biophysical Characterization
$80K - $95K *
Unlock innovative biophysical analysis for client protein projects. Design experiments, validate methods, and communicate results effectively. Collaborate independently while supporting a diverse rang...
3 days ago
Principal Program Manager Integration & Separation Office
$125K - $150K *
Contribute to successful project execution by managing initiatives, collaborating across teams, and ensuring effective processes are in place while driving continuous improvement and delivering qualit...
2 weeks ago
Principal Research Scientist - Product development
$110K - $130K *
Pioneer the development of innovative parenteral drug products for animal health. Engage in formulation development, managing lab activities, and coordinating with internal and external partners while...
3 weeks ago
Scientist, Analytical Chemistry
$103K - $192K *
Drive innovative research in chemical analysis to enhance drug development. Collaborate with cross-functional teams, run complex experiments, and interpret data to advance drug discovery and technolog...
2 weeks ago
Scientist, Analytical Chemistry
$103K - $192K *
Join a team that's dedicated to advancing drug discovery through innovative experimental design and analysis, ensuring drug development meets safety and efficacy standards while collaborating with cro...
2 weeks ago
$77K - $96K *
Lead the charge in developing, implementing, and overseeing analytical strategies in food safety and quality assurance, while managing a skilled team to ensure compliance with regulatory standards and...
1 week ago
Scientist, Analytical Development
$93K - $174K *
Support the development and optimization of analytical methods for radiopharmaceuticals, ensuring adherence to quality, safety, and regulatory standards. Collaborate across functions to generate high...
1 week ago
Principal Engineer, Advanced Manufacturing
$150K - $200K *
Transform manufacturing operations by leading the commissioning of high-volume lines, optimizing workflows, and implementing MES systems to enhance productivity and scalability in a dynamic environmen...
3 weeks ago
Senior Director, In Vitro Biology & Molecular Pharmacology
$230K - $300K *
Transform drug discovery by leading a high-performing team to innovate and execute strategies in small molecule therapeutics, focusing on novel modalities and challenging targets, while driving scient...
2 weeks ago
Senior Research Advisor / Research Advisor, Analytical Chemistry - TIDES, SMDD
$126K - $204K *
Lead analytical strategies for early-phase peptide and oligonucleotide programs. Collaborate with multidisciplinary teams to ensure successful GLP/GMP execution and regulatory compliance for drug deve...
2 weeks ago
Senior Principal Mission Engineer
$153K - $190K *
Join a team that's empowering the U.S. Air Force's Big Safari mission by providing expert mission engineering support for advanced Electromagnetic Battle Management systems and enhancing cross-platfor...
3 weeks ago
Principal Scientist, Applied AI, Immune Pathway Discovery
$117K - $201K *
Empower scientific discovery by designing and piloting AI solutions that drive impactful therapeutic advancements. Collaborate across teams to translate insights into capabilities, enhancing R&D in im...
3 days ago
Principal Scientist, Applied AI, Immune Pathway Discovery
$117K - $201K *
Engineer transformative AI solutions in Immunology Discovery, collaborating with scientists and tech teams to enhance our drug discovery portfolio and drive scientific innovation through interdiscipli...
3 days ago
Principal Scientist, Applied AI, Immune Pathway Discovery
$117K - $201K *
Empower advanced discovery in immunology by designing AI solutions that drive scientific innovation. Collaborate with teams to transform prototypes into scalable applications, enhancing research capab...
3 days ago
Process Development Senior Principal Scientist
$157K - $213K *
Join a team that drives innovation in drug product development, leveraging your expertise in formulation and process to lead cross-functional teams in transforming complex biologics into commercial pr...
2 weeks ago
$83K - $106K *
Empower innovation by driving product development in microbiology. Leverage your scientific expertise to contribute to high-quality projects that enhance customer satisfaction while adhering to string...
2 weeks ago
$142K - $200K *
Lead innovative bioprocess development in mammalian cell culture and harvest, fostering cross-functional collaboration and ensuring regulatory compliance to bring diverse biopharmaceuticals from devel...
1 week ago
Scientist/Sr Scientist, Vaccine Discovery
$72K - $189K *
Unlock the potential of vaccine discovery through hands-on molecular biology and immunoassays, supporting candidate screening, data generation, and lab operations to advance innovative vaccine researc...
6 days ago
$80K - $95K *
Join our team to ensure product quality through microbiological and analytical testing, compliance with GMP standards, and environmental monitoring, while contributing to the validation of life-saving...
1 week ago
Manager, End User Services & Lab Support
$135K - $165K *
Elevate employee productivity through dynamic IT support and lab services. Lead service delivery, platform administration, and user onboarding in a fast-paced biotech environment, ensuring seamless op...
2 weeks ago
Principal Scientist I/II, Oligonucleotide Chemistry & Innovation
$108K - $201K *
Drive innovation in RNA therapeutic development by leading oligonucleotide chemistry efforts and mentoring a team of scientists, all while collaborating on breakthrough therapies in a fast-paced resea...
Reposted 2 weeks ago
Senior Principal Scientist Oligonucleotides
$157K - $213K *
Lead the charge in oligonucleotide process innovation, driving sustainable manufacturing and technology expansion while mentoring a dynamic team in a collaborative, growth-focused environment...
5 days ago
Senior Principal Scientist Oligonucleotides
$157K - $213K *
Elevate your career by leading a multidisciplinary team to innovate sustainable oligonucleotide manufacturing processes while driving capacity expansion and ensuring technology transfers to GMP facili...
5 days ago
$95K - $115K *
Elevate your career by leading innovative QC projects, collaborating with teams, conducting advanced analytical testing, and ensuring compliance while training fellow scientists in a supportive, fast...
Reposted 6 days ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.