Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal Research Scientist I (Analytical R&D for LNP and Small Molecule)
$100K - $130K *
Shape the future of pharmaceutical development by leading analytical projects in drug substance and product formulation. Collaborate with R&D teams to innovate and optimize strategies for new chemical...
1 week ago
Research Laboratory Supervisor
$75K - $95K *
Join a team that's revolutionizing agricultural diagnostics through molecular assay design, optimization, and data analysis. Collaborate to deliver high-quality solutions for crop improvement in a dyn...
3 weeks ago
Sr Principal/Principal Software Engineer, App
$204K - $348K *
Engineers are sought to build secure, high-performance systems for seamless AI collaboration. Design UI/APIs, optimize database architecture, and drive cross-functional teamwork to enhance scientific...
3 weeks ago
Sr. Technical Project Manager, HID Professional Services
$103K - $125K *
Lead the charge in managing forensic DNA validation projects, driving cross-functional collaboration and delivering impactful results that exceed customer expectations and streamline workflows for for...
Today
Sr. Technical Project Manager, HID Professional Services
$103K - $125K *
Lead and drive forensic DNA validation and Rapid DNA projects, ensuring timely delivery and high-quality outcomes through collaboration with stakeholders and cross-functional teams...
Today
P-5010 Scientist II, Reagents Sustaining and Applications
$139K - $188K *
Transform your career by leading advancements in Chromium Single Cell products. Collaborate across teams to enhance product quality through innovative experimental design and meticulous process improv...
Reposted yesterday
$75K - $90K *
Advance bioprocess development by supporting a team in creating and innovating purification technologies for biologics, focusing on diverse therapeutic modalities and collaborative experimentation...
2 days ago
$70K - $95K *
Elevate operational excellence by providing advanced analytical testing and technical leadership while mentoring staff and ensuring compliance in a dynamic laboratory setting supporting both internal...
3 weeks ago
Senior Research Associate, Proteomics
$106K - $126K *
Engineer innovative proteomics workflows and drive drug discovery projects in a dynamic team. Apply your expertise in mass spectrometry while contributing to high-quality data generation and optimizin...
2 weeks ago
Lead Scientist, Molecular & Cellular Biology
$100K - $130K *
Innovate Biopharma product development by leading assay design, validation, and documentation under cGMP guidelines. Collaborate with teams, mentor peers, and utilize advanced techniques to ensure com...
1 week ago
$75K - $95K *
Shape the future of pharmaceutical manufacturing by developing processes, ensuring compliance, and enhancing production efficiency while leading cross-functional teams to drive innovation and operatio...
3 weeks ago
$175K - $200K *
Empower innovation by leading the design and development of advanced medical devices. Drive cross-functional collaboration to ensure optimal performance and compliance in creating safe, effective solu...
3 weeks ago
Sr. Scientist, Clinical Pharmacology
$140K - $189K *
Unlock potential by leading clinical pharmacology efforts to analyze, interpret, and model PKPD data for RNAi therapeutics. Collaborate with cross-functional teams to drive decision-making and support...
3 weeks ago
Senior Scientist, in vivo Pharmacology, Genetically Engineered Models – Comparative Medicine
$103K - $192K *
Deliver cutting-edge animal models to enhance drug discovery efforts. Collaborate within a multidisciplinary team to innovate genome engineering techniques, ensuring scientific rigor while shaping imp...
2 weeks ago
$152K - $190K *
Join a team that's shaping the future of healthcare through innovative software solutions. As a technical leader, you'll drive the design and development of next-gen clinical data platforms while ment...
Reposted yesterday
Senior Scientist/Massachusetts Licensed Site Professional (LSP) Scientist
$90K - $120K *
Transform environmental projects by leading site investigations, evaluating risks, and ensuring regulatory compliance. Drive innovation in technical solutions while mentoring staff and developing clie...
3 weeks ago
Director Analytical Research and Development
$120K - $150K *
Lead a high-performing analytical R&D team, coordinating cross-functional efforts to deliver innovative solutions while ensuring compliance with industry standards and fostering a collaborative enviro...
2 weeks ago
$130K - $150K *
Transform the quality landscape of a manufacturing site by leading end-to-end quality strategies, assuring compliance, instilling a proactive quality culture, and driving continuous improvement across...
Reposted 2 weeks ago
$130K - $150K *
Join us in leading the Quality function at our site, ensuring product excellence and compliance. Drive strategic initiatives in Quality Control, Assurance, and regulatory compliance while fostering a...
Reposted 2 weeks ago
Principal ML/AI Cheminformatics Scientist
$106K - $176K *
Transform drug discovery by developing AI-driven cheminformatics models that enhance decision-making and optimize compound selection, addressing complex challenges with cutting-edge technology and col...
2 days ago
$100K - $130K *
Help us advance therapeutic development by leading late-stage ADC conjugation processes, conducting in-depth experiments, and collaborating with multidisciplinary teams to ensure timely, effective res...
2 days ago
Scientist, ADME & BioAnalytical
$90K - $130K *
Engage in leading DMPK and ADME efforts, optimizing drug properties, and ensuring regulatory compliance through collaboration with internal and external teams on drug development projects...
2 weeks ago
Senior Principal Machine Learning Scientist, AI Biology & Translation (AIBT)
$202K - $376K *
Lead the charge in advancing AI for biology by pioneering innovative genomic models and driving biological discovery, while mentoring a team and influencing organizational strategies for therapeutic i...
3 days ago
$100K - $130K *
Lead the reliability function for sterile pharma manufacturing. Oversee strategies for maintenance, compliance, and equipment lifecycle, ensuring operational excellence and continuity in a dynamic tea...
4 weeks ago
Senior Applied Scientist, Funnel Agentic Intel
$167K - $226K *
Innovate by developing AI systems that enhance advertising workflows, simplify campaign management, and improve advertiser outcomes through data-driven insights and autonomous actions. Join a dedicate...
Yesterday
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.