Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$100K - $130K *

Drive large-scale digital transformation initiatives by leading Agile teams and managing financials, ensuring effective collaboration between stakeholders across enterprise project deliveries...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$75K - $100K *

Champion client engagement by driving growth through insight-led analysis. Collaborate with cross-functional teams to deliver tailored solutions that enhance client profitability using advanced analyt...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$175K - $200K *

Lead product initiatives within a critical technology platform, focusing on user needs, problem-solving, and seamless delivery while collaborating with engineering and design to enhance educational ex...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $120K *

Play a key role in leading clinical research activities across regions, ensuring compliance, quality, and timely delivery. Engage with cross-functional teams and mentor junior staff, while minimizing...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Champion oversight of study quality and site management while mentoring teams. Lead project timelines, ensure compliance, and enhance investigator communications in a remote environment with minimal t...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$230K - $322K *

Join the AI Engineering team to create Reddit-native LLMs, enhancing model safety and performance through innovative evaluation and fine-tuning pipelines, while collaborating with expert engineers to...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$200K *

Transform the future of biostatistics by leading a dynamic team in clinical trial design and analysis, shaping strategic initiatives, and driving operational excellence while mentoring talent and coll...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $245K *

Transform clinical data architecture and pipelines, leading strategic initiatives in AI to enhance efficiency and drive innovation in healthcare data management, collaborating cross-functionally to en...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $130K *

Partner with us to provide vital technical support and training for our cutting-edge proteomics portfolio. Your expertise will assist clients in optimizing workflows, enhancing research, and driving i...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$122K - $172K *

Collaborate with HR leaders to develop data-driven insights, create analytical dashboards, and enhance decision-making processes using strong research methods and AI workflows, ultimately improving or...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$175K - $225K *

Transform your career by driving global commercial strategies in asset management services, enhancing customer relationships, and leading a high-performing team to achieve profitable growth and market...

US-AnywhereRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$105K - $125K *

Pioneer the development of robust software solutions in eDiary and clinical data platforms, leveraging modern technologies to enhance patient engagement and ensure regulatory compliance while collabor...

US-AnywhereRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in designing and automating cloud infrastructures across AWS, Azure, and GCP. Empower clients to drive cloud adoption through secure, scalable solutions, and mentor teams while enhanci...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $180K *

Transform regulated identity governance by architecting solutions that ensure compliance and security across enterprise platforms, driving strategic initiatives in Identity & Access Management with a...

US-AnywhereRemote

4 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$120K - $128K *

Lead the charge in ocean science innovation by managing complex programs for NOAA. Synthesize data to shape critical policies and ensure successful international collaborations for ocean health advoca...

US-AnywhereRemote

6 days ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$169K - $208K *

Build and enhance autonomous penetration testing agents that mimic human expertise in vulnerability assessments, ensuring production safety and reliability at scale, while collaborating closely with o...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Lead the charge in clinical trial programs, providing statistical oversight and mentorship to teams. Collaborate on protocol design, statistical analysis, and regulatory submissions, ensuring complian...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$113K - $150K *

Join a team that's shaping air quality solutions! Drive product strategies, manage life cycles, and engage with customers to enhance market offerings in the gas analyzer portfolio for a cleaner, safer...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$240K - $360K *

Lead the charge in medical safety for pharmaceutical products, ensuring robust benefit-risk assessments and regulatory compliance. Oversee cross-functional teams to enhance patient safety and product...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Transform the content authoring landscape by leading product strategy and managing a team of product managers to create innovative workflows that enhance user experiences across multiple business unit...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$130K - $160K *

Lead the charge in delivering innovative, scalable solutions across healthcare, marketing, and logistics through technical authority in architecture design, hands-on development, and mentorship in a d...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $205K *

Join a dynamic team as you lead cross-functional initiatives to drive the development of digital features, balancing strategic insight with execution smarts to deliver impactful solutions...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$144K - $176K *

Pioneer innovative AI solutions that shape personalized student learning experiences. You'll design systems, build evaluations, and integrate features across the stack, ensuring high-quality user inte...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Pioneer innovative solutions by leading software implementation projects that enhance healthcare analytics and data integration. Manage client relationships while ensuring projects are executed on tim...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Deliver comprehensive oversight of laboratory clinical trials to ensure compliance and quality assurance. Manage complex projects from initiation to closeout while fostering team collaboration and ali...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.