Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$110K - $130K *

Execute and lead scientific research in drug formulation and delivery for protein-based therapeutics. Collaborate with cross-functional teams to design, develop, and optimize manufacturing processes...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Manage the design and delivery of innovative LC/MS systems for bioprocesses, coordinating across teams to transform concepts into operational solutions that enhance analytical performance and technolo...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$116K - $177K *

Unlock your potential by leading interdisciplinary teams in developing innovative research and product solutions within clinical and life sciences, leveraging your expertise in experimental design and...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $130K *

Innovate by leading the research in affinity-based technologies and separations. Drive advancements in biomaterials and chromatography systems, bridging bioengineering and analytical science to create...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Take ownership of complex field studies proving AI, data, and cloud solutions for marketers. Design experiments, analyze customer data, and mentor junior staff while influencing enterprise-scale decis...

Reposted today

  •   5 - 7 years exp.  •   Business Services

$90K - $120K *

Drive innovative drug development by leading complex R&D efforts, executing experiments, analyzing critical data, and collaborating effectively across teams to ensure product quality and regulatory co...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Drive your career forward by leading analytical method development in a dynamic environment. Manage projects, mentor teams, and ensure compliance with cGMP standards. Join us to foster innovation and...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Innovate with us to design advanced digital and semantic technologies that transform pharmaceutical development, improve laboratory workflows, and enhance scientific data integration for next-generati...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$131K - $196K *

Deliver innovative oligonucleotide solutions while leading product development and technical projects. Collaborate in a hands-on lab environment, empowering teams through mentorship and driving excell...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $155K *

Engage in the development and implementation of analytical methods for APIs, ensuring compliance with industry standards. Collaborate with project teams while applying advanced techniques and leading...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $175K *

Support and lead complex hardware/software development projects in life sciences. Oversee planning, execution and collaboration to ensure innovative solutions delivery while managing risks, budgets, a...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $165K *

Transform product development by leading QC method innovation, optimizing processes, and ensuring robust assay transfer from R&D to manufacturing. Collaborate across teams to drive success in bringing...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $120K *

Engineer innovative synthetic routes for new chemical products, manage multiple R&D projects, and collaborate on scale-up activities. Leverage your expertise to drive product development in a fast-pac...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Empower innovative chemical synthesis and development by optimizing existing routes and designing new methodologies. Collaborate with teams to ensure safe, efficient lab operations while leading proje...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $210K *

Reimagine the future of cell therapy as an innovative leader driving process development and optimization. Collaborate across teams and external partners to enhance the Cellares platform while mentori...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Develop innovative LC-HRMS methodologies for metabolite analysis. Lead studies on diverse therapeutic modalities, delivering high-quality reports while collaborating with cross-functional teams to dri...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Unlock your potential in a pivotal role enhancing automation in laboratory workflows, collaborating to translate manual assays to automated platforms, and ensuring compliance for cutting-edge drug dev...

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$133K - $157K *

Join a dynamic team to advance preclinical discovery in bioanalytical sciences, optimizing methods and managing studies, while fostering a culture of innovation aimed at improving mental health soluti...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead transformative projects by leveraging digital technologies to enhance lab automation, data integration, and scientific workflows, enabling innovative research in pharmaceutical development across...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead the charge in building advanced digital lab environments that integrate AI, robotics, and semantic technologies, transforming pharmaceutical development and enhancing scientific workflows across...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Lead the development of innovative AI solutions in preclinical research, managing complex predictive models and agentic systems. Collaborate with stakeholders to ensure secure deployment and complianc...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $222K *

Empower our biologics team! Lead the formulation development of complex biologics, driving scientific innovation and collaboration. Shape early-stage strategies and manage multiple projects with a div...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Lead the charge in advancing upstream processing methodologies for mammalian cell culture, facilitating successful tech transfer to cGMP manufacturing while managing multiple projects and driving inno...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $140K *

Unlock potential by leading applied bacteriology programs to enhance global health through innovative research and collaboration. Drive product development and ensure compliance while mentoring future...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$111K - $206K *

Unlock potential by spearheading innovative molecular diagnostic assays in oncology. Lead lab-based projects, mentor peers, and translate cutting-edge research into impactful solutions, fostering coll...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.