Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$156K - $190K *
Drive innovation as a technical leader in R&D, focusing on dental chemical consumables. Lead complex experiments, mentor junior scientists, and ensure product excellence while adhering to quality stan...
3 weeks ago
$80K - $95K *
Optimize E&L study execution and compliance through strategic leadership, ensuring high-quality data for regulatory submissions while mentoring teams and aligning goals with product development initia...
3 weeks ago
Principal Scientist, Analytical Sciences
$160K - $190K *
Join a team that's shaping the future of analytical science for synthetic oligonucleotide therapies. Manage CMO labs, develop methods, and ensure compliance for drug substances throughout development...
2 weeks ago
Principal Scientist - ADME - Site Based, Princeton, NJ
$113K - $154K *
Champion innovative ADME-Tox projects, collaborate with multidisciplinary teams, and lead scientific exploration while mentoring staff, driving personal growth and organizational success through effec...
Reposted 5 days ago
Senior Scientist / Principal Scientist, Bioprocess Sciences
$120K - $198K *
Drive bioprocess development for bacterial protein production, overseeing scale-up strategies and external partnerships. Collaborate cross-functionally to optimize purification processes in a dynamic...
2 weeks ago
Principal Scientist-Analytical Research & Development (ARD)
$140K - $155K *
Engage in the development and implementation of analytical methods for APIs, ensuring compliance with industry standards. Collaborate with project teams while applying advanced techniques and leading...
1 week ago
Senior Scientist I, Product Development
$150K - $165K *
Transform product development by leading QC method innovation, optimizing processes, and ensuring robust assay transfer from R&D to manufacturing. Collaborate across teams to drive success in bringing...
1 week ago
$90K - $120K *
Explore the forefront of synthetic biology by engineering phages in an innovative lab, collaborating closely with teams to generate impactful experimental data and advance cutting-edge research in a d...
5 days ago
$90K - $120K *
Accelerate progress at the forefront of synthetic biology by engineering and testing bacteriophages in a collaborative lab environment, driving innovation through hands-on molecular biology techniques...
5 days ago
Principal Scientist 1 - Chemical Research & Development
$100K - $130K *
Empower innovative chemical synthesis and development by optimizing existing routes and designing new methodologies. Collaborate with teams to ensure safe, efficient lab operations while leading proje...
1 week ago
Principal Scientist, Engineering
$173K - $272K *
Take ownership of biologics commercialization processes by leading product development, scale-up, technology transfer, and regulatory submissions to ensure timely delivery of innovative therapies and...
Reposted 2 weeks ago
Supervising Principal Scientist, Process Development
$90K - $210K *
Reimagine the future of cell therapy as an innovative leader driving process development and optimization. Collaborate across teams and external partners to enhance the Cellares platform while mentori...
1 week ago
Principal Scientist, Regulatory Affairs - CMC
$168K - $285K *
Lead strategic Regulatory CMC initiatives for the Cardiovascular portfolio, ensuring compliance and successful product lifecycle management while developing and mentoring a high-performing team of Reg...
Yesterday
Principal Scientist, Regulatory Affairs - CMC
$168K - $285K *
Champion regulatory excellence by leading CMC strategies for the cardiovascular portfolio. Drive product lifecycle management and team development while ensuring compliance with global regulations. Co...
Yesterday
Senior Scientist, Bioanalytical Science
$133K - $157K *
Join a dynamic team to advance preclinical discovery in bioanalytical sciences, optimizing methods and managing studies, while fostering a culture of innovation aimed at improving mental health soluti...
3 days ago
Principal Scientist: ARD Compliance Lead
$106K - $176K *
Advance compliance and data integrity in ARD through cross-functional collaboration. Drive continuous improvement and uphold quality standards while effectively managing GMP processes and team initiat...
1 week ago
Principal Associate Scientist, Biology
$108K - $122K *
Drive advancements in RNAi target discovery by independently executing molecular biology assays, managing cell cultures, and analyzing data to support neuroscience projects in a collaborative lab envi...
1 month ago
Principal Scientist - Process Development, Upstream
$100K - $130K *
Lead the charge in advancing upstream processing methodologies for mammalian cell culture, facilitating successful tech transfer to cGMP manufacturing while managing multiple projects and driving inno...
Yesterday
$120K - $140K *
Unlock potential by leading applied bacteriology programs to enhance global health through innovative research and collaboration. Drive product development and ensure compliance while mentoring future...
1 week ago
Principal Scientist, Analytical Development
$130K - $179K *
Lead the charge in advancing analytical development for drug substance projects, from preclinical to commercial phases. Collaborate with cross-functional teams to optimize methods and ensure complianc...
3 weeks ago
Principal Scientist, Product & Process Technology
$100K - $130K *
Drive technical transfer and process optimization for Oral Solid and Liquid products, ensuring compliance, efficiency, and safety. Collaborate with R&D and manufacturing teams to resolve issues and su...
3 days ago
Senior Scientist, Bioanalytics
$100K - $130K *
Join a team that's dedicated to enhancing quality through data analysis and technical leadership, driving innovation in bioanalytical methods to support global health initiatives and improve product s...
1 week ago
$90K - $120K *
Join a team that’s committed to driving agricultural innovation by conducting impactful research in plant nematology, enhancing crop resistance, and collaborating across disciplines to support farmers...
1 week ago
$90K - $120K *
Empower innovation in coatings by providing technical support to distributors and customers. Engage in laboratory projects, optimize resources, and grow market presence in Transportation and Plastics...
3 weeks ago
Senior Scientist, Fermentation - IR&D, Product Development
$120K - $150K *
Champion innovation in upstream fermentation development, driving collaboration across teams to optimize processes for novel vectors. Utilize advanced technologies to enhance product solutions and sup...
Today
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.