Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$110K - $130K *

Empower your career by leading strategic application initiatives, collaborating with cross-functional teams to enhance investment solutions, and driving continuous improvement across the application l...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $135K *

Lead the charge in human services policy consulting to enhance operations and compliance for government agencies. Utilize expertise in federal regulations and stakeholder engagement to provide actiona...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$180K - $215K *

Lead the charge in driving regional sales success through strategic execution, team leadership, and cross-functional collaboration. Foster strong customer relationships and ensure alignment with corpo...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $94K *

Unlock potential by joining a dynamic team that supports military transitions into civilian roles. Gain hands-on experience in IT project management while collaborating with industry leaders to enhanc...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$77K - $106K *

Deliver exceptional home health nursing care, collaborating with healthcare teams to develop personalized care plans, monitor patient progress, and educate families, ensuring quality support in patien...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $106K *

Join a team that delivers personalized home health care, empowering patients to regain independence. Collaborate with healthcare professionals to manage care plans, monitor progress, and educate famil...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Empower our data platform by designing, building, and operating core capabilities. Collaborate with teams to enhance ingestion, storage, and API functionalities, ensuring scalability and resilience wh...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $185K *

Shape the future of healthcare strategy by leading brand initiatives, mentoring talent, and driving impactful storytelling to elevate strategic excellence across teams and agency collaborations...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Contribute to the design and execution of clinical studies, ensuring data integrity and quality. Collaborate cross-functionally to drive study activities and support regulatory efforts, while enhancin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape the future of cancer treatment by collaborating with experts to create individualized radiation therapy plans. Leverage advanced tools and techniques in a supportive, fully remote environment fo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$142K - $195K *

Unlock potential by designing secure, enterprise-scale solutions that protect critical data and systems. Collaborate with stakeholders to assess threats, innovate security architecture, and enhance en...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in transforming IT support for healthcare centers by evaluating, planning, and executing transitions to AMSURG Managed IT Services, while architecting cloud solutions with Microsoft 36...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Join a team that's redefining healthcare economics by analyzing costs and outcomes to enhance clinical strategies. Utilize advanced data analytics to drive actionable insights and improved patient car...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $125K *

Lead and manage diverse acoustics projects, mentoring team members while collaborating with top engineers and architects on high-impact designs across various sectors, including healthcare, education...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$100K - $120K *

Empower a dynamic sales team as a player-coach, driving growth in the dental market. Lead, coach, and sell while fostering accountability and performance improvement to achieve team goals and enhance...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$135K - $140K *

Join a team that's shaping the future of cybersecurity by leading strategic resilience initiatives. Drive risk management, incident response, and security architecture while collaborating with senior...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Join a dynamic team to lead and scale clinical operations, overseeing performance and process optimization. Build accountable teams, manage metrics, and partner with stakeholders to enhance operationa...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Champion the growth of a clinic by leading a team of clinicians, managing operations, and enhancing services for children with Autism. Drive quality care and foster a supportive environment for famili...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $190K *

Join a dynamic team to architect and implement scalable technology solutions that enhance data-driven decision-making and operational efficiency across multidisciplinary projects...

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $160K *

Drive WellTheory's growth in benefits consulting by cultivating strong partnerships, educating consultants, and supporting client strategies. This hands-on, individual contributor role requires strate...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Join a team that's dedicated to delivering exceptional patient care and fostering a collaborative culture. As a leader, you'll guide clinic teams, enhance patient experiences, and drive innovative car...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Lead the charge in empowering strategic partners by delivering technical capabilities, driving customer opportunities, and fostering scalable solutions throughout the partner lifecycle to achieve meas...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $206K *

Drive strategic risk management initiatives by leading regulatory audits, enhancing operational processes, and fostering cross-functional collaboration to minimize financial impacts and improve audit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$114K - $140K *

Join us to lead innovative health care policy research, utilizing large datasets to evaluate and design impactful programs. Collaborate with multidisciplinary teams to influence Medicare and Medicaid...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$130K - $160K *

Transform financial operations by leading accounting, treasury, and payment processes. Ensure accuracy and integrity in financial reporting while enhancing systems and controls for scalable growth in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.