Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$95K - $100K *

Transform complex member care by leading clinical triage and program management for In Home Clinical Services and Personal Care Attendant programs, ensuring compliance and optimizing outcomes through...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$220K *

Shape and lead project teams through complex analyses, delivering actionable insights while building strong client relationships and mentoring junior staff across diverse business challenges...

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$135K - $160K *

Empower our data platform by designing, building, and operating core capabilities. Collaborate with teams to enhance ingestion, storage, and API functionalities, ensuring scalability and resilience wh...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $185K *

Shape the future of healthcare strategy by leading brand initiatives, mentoring talent, and driving impactful storytelling to elevate strategic excellence across teams and agency collaborations...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Contribute to the design and execution of clinical studies, ensuring data integrity and quality. Collaborate cross-functionally to drive study activities and support regulatory efforts, while enhancin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$102K - $177K *

Lead strategic marketing initiatives in Spine Robotics, shaping innovation and product strategies. Collaborate with cross-functional teams to drive market insights and technology advancements, ensurin...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $114K *

Engage with clients to unlock their potential through diverse therapeutic approaches. Enjoy flexible scheduling and competitive compensation while making a meaningful impact in the lives of individual...

Today

  •   Less than 5 years exp.  •   Healthcare

$93K - $114K *

Engage with clients to unlock their potential through diverse therapeutic approaches. Enjoy flexible scheduling and competitive compensation while working collaboratively in a supportive environment a...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Shape the future of cancer treatment by collaborating with experts to create individualized radiation therapy plans. Leverage advanced tools and techniques in a supportive, fully remote environment fo...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$142K - $195K *

Unlock potential by designing secure, enterprise-scale solutions that protect critical data and systems. Collaborate with stakeholders to assess threats, innovate security architecture, and enhance en...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in transforming IT support for healthcare centers by evaluating, planning, and executing transitions to AMSURG Managed IT Services, while architecting cloud solutions with Microsoft 36...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Join a team that's redefining healthcare economics by analyzing costs and outcomes to enhance clinical strategies. Utilize advanced data analytics to drive actionable insights and improved patient car...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $125K *

Lead and manage diverse acoustics projects, mentoring team members while collaborating with top engineers and architects on high-impact designs across various sectors, including healthcare, education...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$135K - $140K *

Join a team that's shaping the future of cybersecurity by leading strategic resilience initiatives. Drive risk management, incident response, and security architecture while collaborating with senior...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Join a dynamic team to lead and scale clinical operations, overseeing performance and process optimization. Build accountable teams, manage metrics, and partner with stakeholders to enhance operationa...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $160K *

Drive WellTheory's growth in benefits consulting by cultivating strong partnerships, educating consultants, and supporting client strategies. This hands-on, individual contributor role requires strate...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K *

Shape the future of assisted living by leading daily operations, ensuring high-quality services, and fostering a motivated team. Drive financial success while maintaining compliance and enhancing resi...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $90K *

Join a team that's dedicated to enhancing patient care through effective utilization review. Collaborate with healthcare professionals to ensure compliance and quality in mental health services while...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $206K *

Drive strategic risk management initiatives by leading regulatory audits, enhancing operational processes, and fostering cross-functional collaboration to minimize financial impacts and improve audit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $100K *

Lead the clinical team to deliver exceptional care, fostering relationships with residents, families, and healthcare providers while mentoring staff and enhancing satisfaction in a dynamic healthcare...

Today

  •   Less than 5 years exp.  •   Healthcare

$213K - $240K *

Transform clinical development by leading statistical strategy for trials, ensuring quality deliverables and regulatory compliance while collaborating across functions in a dynamic biotech environment...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$359K - $431K *

Shape your career by leading the global medical strategy for a dynamic portfolio. Collaborate with cross-functional teams to drive evidence generation, stakeholder engagement, and strategic execution...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Transform financial operations by leading accounting, treasury, and payment processes. Ensure accuracy and integrity in financial reporting while enhancing systems and controls for scalable growth in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Elevate your career by supporting critical cybersecurity initiatives for the Air Force. Collaborate with a dynamic team to enhance system security, manage vulnerabilities, and ensure compliance in a f...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $175K *

Lead the charge in delivering insights through advanced research and analysis, managing multiple projects, guiding team performance, and enhancing client relationships in the life sciences consulting...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.