Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$100K - $120K *

Advance your career by developing a new influencer partnership channel that boosts patient engagement and drives revenue. You'll source and negotiate deals while optimizing partnerships, all in a fast...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $135K *

Empower strategic client partnerships by leading multifaceted engagements in a dynamic environment, leveraging healthcare expertise to devise innovative solutions that foster collaborative teamwork an...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Innovate and lead client engagements, driving strategic insights and integrated solutions in a fast-paced healthcare environment while mentoring cross-functional teams towards operational excellence a...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$107K - $224K *

Join a team that's dedicated to providing high-quality ambulatory care. You'll manage a panel of patients, promote collaboration, and deliver comprehensive primary care services while mentoring clinic...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Empower oncology research by leveraging real-world evidence and clinical expertise. Collaborate with cross-functional teams to develop innovative solutions that enhance cancer treatment and support bi...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$107K - $178K *

Optimize quality assurance processes to ensure manufacturing excellence and compliance. Collaborate with cross-functional teams to implement improvements, lead investigations, and support quality metr...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $135K *

Lead the charge in human services policy consulting to enhance operations and compliance for government agencies. Utilize expertise in federal regulations and stakeholder engagement to provide actiona...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$167K - $191K *

Elevate your career by leading innovative data strategies and analytics for rare neurology diseases. Drive evidence generation and analytics across a diverse portfolio, collaborating with cross-functi...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Lead the charge in driving regional sales success through strategic execution, team leadership, and cross-functional collaboration. Foster strong customer relationships and ensure alignment with corpo...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $235K *

Lead the charge in transforming tax technology by developing innovative solutions that enhance operational efficiency and compliance. Collaborate with cross-functional teams to drive digital transform...

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $94K *

Unlock potential by joining a dynamic team that supports military transitions into civilian roles. Gain hands-on experience in IT project management while collaborating with industry leaders to enhanc...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$118K - $172K *

Transform the radiology department by optimizing operations, ensuring compliance, and leading staff development. Drive strategic initiatives and budget management while enhancing patient care quality...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $100K *

Transform complex member care by leading clinical triage and program management for In Home Clinical Services and Personal Care Attendant programs, ensuring compliance and optimizing outcomes through...

Today

  •   Less than 5 years exp.  •   Healthcare

$220K *

Shape and lead project teams through complex analyses, delivering actionable insights while building strong client relationships and mentoring junior staff across diverse business challenges...

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$135K - $160K *

Empower our data platform by designing, building, and operating core capabilities. Collaborate with teams to enhance ingestion, storage, and API functionalities, ensuring scalability and resilience wh...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $185K *

Shape the future of healthcare strategy by leading brand initiatives, mentoring talent, and driving impactful storytelling to elevate strategic excellence across teams and agency collaborations...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Contribute to the design and execution of clinical studies, ensuring data integrity and quality. Collaborate cross-functionally to drive study activities and support regulatory efforts, while enhancin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$102K - $177K *

Lead strategic marketing initiatives in Spine Robotics, shaping innovation and product strategies. Collaborate with cross-functional teams to drive market insights and technology advancements, ensurin...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $114K *

Engage with clients to unlock their potential through diverse therapeutic approaches. Enjoy flexible scheduling and competitive compensation while making a meaningful impact in the lives of individual...

Today

  •   Less than 5 years exp.  •   Healthcare

$93K - $114K *

Engage with clients to unlock their potential through diverse therapeutic approaches. Enjoy flexible scheduling and competitive compensation while working collaboratively in a supportive environment a...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Shape the future of cancer treatment by collaborating with experts to create individualized radiation therapy plans. Leverage advanced tools and techniques in a supportive, fully remote environment fo...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$142K - $195K *

Unlock potential by designing secure, enterprise-scale solutions that protect critical data and systems. Collaborate with stakeholders to assess threats, innovate security architecture, and enhance en...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in transforming IT support for healthcare centers by evaluating, planning, and executing transitions to AMSURG Managed IT Services, while architecting cloud solutions with Microsoft 36...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Join a team that's redefining healthcare economics by analyzing costs and outcomes to enhance clinical strategies. Utilize advanced data analytics to drive actionable insights and improved patient car...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $125K *

Lead and manage diverse acoustics projects, mentoring team members while collaborating with top engineers and architects on high-impact designs across various sectors, including healthcare, education...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.