Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$80K - $95K *

Lead the end-to-end recruiting process, enhancing strategies and partnerships across departments. Drive high-volume hiring with autonomy, ensuring a seamless candidate experience while collaborating c...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Lead and develop a high-performing team to expand behavioral healthcare access. Drive regional referral growth through strategic partnerships, data-driven decision-making, and effective outreach while...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in managing end-to-end Phase 1-3 clinical trials, ensuring operational excellence and compliance while collaborating with cross-functional teams to drive strategic clinical development...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform daily operations of the Infusion Center by enhancing performance, productivity, and efficiency through strategic management and process improvement initiatives, ensuring optimal service deli...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $100K *

Lead the charge in building a robust accounting function, overseeing monthly closes, revenue reconciliation, and financial reporting. Collaborate closely with the Controller to enhance processes and s...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join a team that's dedicated to developing physician education programs that enhance scientific knowledge of cardiovascular therapies and ensure effective learning experiences for healthcare professio...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$306K - $344K *

Drive the evolution of Clinical Compliance and Systems, ensuring scalable, compliant clinical trial execution. Collaborate across functions to shape innovative solutions and lead a high-performing tea...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$180K - $258K *

Shape strategic growth and client relationships across territories by developing tailored sales strategies and leveraging data insights to maximize business impact and foster long-term value in the bi...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $190K *

Unlock end-to-end software solutions by designing and developing scalable features at the intersection of healthcare and technology. Collaborate with cross-functional teams to rapidly deploy impactful...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $192K *

Elevate your career by driving demand in Rheumatology. Build trusted relationships with healthcare professionals and leverage data-driven insights to enhance patient access and outcomes while achievin...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$189K - $246K *

Join a team that's shaping the future of metabolic health by leading a national field medical strategy. Drive cross-functional collaboration, manage a team of experts, and ensure compliance while achi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Lead engineering efforts by writing production code and mentoring a team. Drive modernization initiatives through Java microservices while managing performance and growth of engineers. Collaborate wit...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Transform your career by driving strategic partnerships in healthcare. Leverage your extensive relationships within benefits consulting to influence and expand business opportunities while collaborati...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$135K - $155K *

Support the CTO by managing complex schedules, orchestrating travel, and ensuring seamless operations. Collaborate closely with leadership to prioritize tasks and enhance productivity in a fast-paced...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$270K - $300K *

Pioneer strategic architectural growth in the Northeast, leading multidisciplinary teams to deliver successful projects. Cultivate client relations and drive business development in transportation and...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Technical Services

$250K - $300K *

Optimize patient comfort and safety by delivering exceptional anesthesia care throughout surgical procedures and pain management, ensuring thorough evaluation and communication during preoperative ass...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $105K *

Tackle comprehensive project management for onboarding HME providers, driving digital transformation across healthcare. Collaborate strategically, enhance platform adoption, and leverage data insights...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Transform patient services operations by optimizing programs, enhancing workflows, and driving access initiatives. Collaborate with partners to ensure seamless execution and improve patient experience...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$248K - $341K *

Provide clinical development leadership for multiple programs, enhancing communication and collaboration across functions. Contribute to strategy, oversee trials, present findings, and mentor team mem...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$248K - $341K *

Lead clinical development initiatives across multiple studies, driving collaboration and innovative strategies. Shape and execute clinical trial objectives while fostering relationships with key stake...

Waltham, MARemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $125K *

Champion an innovative Systems Engineer role, collaborating with tech teams and vendors to advance product development, enhance designs, and tackle complex technical challenges in a dynamic environmen...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$104K - $143K *

Join a team that's dedicated to ensuring cGMP compliance through expert QA oversight in commissioning, qualification, and validation activities. Lead a collaborative environment focused on continuous...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $122K *

Grow your career with a dynamic team providing essential home dialysis care. As a key member, you'll assess, educate, and support patients while ensuring effective treatment delivery and enhancing pat...

Today

  •   Less than 5 years exp.  •   Healthcare

$64K - $120K *

Empower clients by delivering expert employee benefits solutions. Collaborate with teams to enhance client strategies, manage projects, and ensure compliance while fostering strong vendor relationship...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$64K - $120K *

Join a dynamic team as you provide expert employee benefits consulting, collaborating with clients and vendors to enhance their insurance strategies and ensure compliance while delivering exceptional...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.