Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$76K - $116K *

Transform lives as you provide quality nursing care in a dynamic environment, developing tailored care plans to enhance resident well-being while collaborating with a multidisciplinary team focused on...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$136K - $187K *

Join a team that's dedicated to empowering patients with generalized Myasthenia Gravis through education and support. As a key point of contact, you'll coordinate care, provide resources, and ensure c...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$280K - $340K *

Transform regulatory strategy and operations across CMC and clinical activities, leading a high-performing team to ensure compliance and successful product approvals from development through post-appr...

United StatesRemote

3 weeks ago

  •   15+ years exp.  •   Information Technology

$180K - $200K *

Drive market adoption and revenue growth in nephrology and transplant sectors. Leverage expert relationships and strategic business plans to promote innovative genetic diagnostic tools and enhance chr...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $150K *

Join a team that's dedicated to improving patient outcomes through expert pharmacy care. Collaborate with healthcare professionals to ensure safe medication practices and provide compassionate support...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Advance patient care by providing evidence-based ABA services as a BCaBA, collaborating within a multidisciplinary team to support children's developmental needs while ensuring flexible scheduling and...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Innovate clinical quality systems for scalable care delivery, ensuring standards meet payer expectations and driving measurable performance improvements across independent health providers...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Deliver impactful sales leadership by managing a dynamic team, driving growth, and fostering key relationships within the healthcare community to achieve regional sales objectives and enhance professi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$66K - $113K *

Champion enterprise portfolio reporting and analytics, developing insights to drive strategic decision-making and enhance project visibility. Collaborate across teams to create actionable dashboards a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$274K - $457K *

Shape the future of hematology clinical development by leading study teams, ensuring regulatory compliance, and guiding strategic initiatives. Your expertise will shape innovative therapies that signi...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$131K - $223K *

Transform federal child welfare initiatives by providing strategic leadership and oversight for a multi-million-dollar contract, ensuring effective management of technical assistance and stakeholder c...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Business Services

$140K - $171K *

Shape investor relations and corporate communications strategies, ensuring effective engagement with stakeholders. Collaborate to execute communication plans, analyze investor trends, and manage inves...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$63K - $123K *

Lead the charge in delivering tailored educational experiences for high school students with disabilities, focusing on therapeutic support and community engagement to foster academic and personal grow...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $160K *

Advance HR technology by leading Workday administration, ensuring optimal system performance, security, and data governance. Collaborate with HR and IT to deliver solutions that enhance business proce...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$61K - $122K *

Transform clinical genetic curation by collaborating cross-functionally to enhance genomic testing, ensuring compliance with guidelines while supporting innovative health initiatives and improving pat...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$122K - $212K *

Unlock potential by leading global compensation strategies that enhance talent retention and recognition. Drive impactful programs, ensure compliance, and collaborate with senior leaders to align comp...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Advance your career by supervising nursing personnel and ensuring optimal patient care. Collaborate with various departments to enhance unit performance and participate in staff training and developme...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$184K - $396K *

Shape the future of healthcare technology by leading clinical informatics initiatives, enhancing patient outcomes, and driving enterprise-wide Epic optimization within a dynamic team of experts dedica...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$104K - $125K *

Advance patient care by providing direct clinical support, coordinating nursing activities, and ensuring high-quality standards. Supervise staff and manage resources effectively to enhance patient out...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $225K *

Lead the charge in architecting scalable technology solutions for institutional clients. Engage with cross-functional teams to create platforms that enhance client experiences, emphasizing technical d...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$88K - $90K *

Champion the development and implementation of individualized treatment plans for children, collaborating with a multi-disciplinary team to enhance early intervention services and ensure comprehensive...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Champion innovative radiology practices to enhance patient care and operational efficiency alongside a dynamic team. Drive clinical excellence and leverage technology to elevate standards across healt...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$204K - $306K *

Lead the charge in integrating AI with scientific workflows, mentoring engineers, and delivering innovative applications that enhance research collaboration. Drive technical strategy and foster a high...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$350K - $375K *

Lead the charge in defining and implementing a modern AI architecture across multiple business units, ensuring scalable, efficient, and secure AI systems that enhance product capabilities and drive in...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$155K - $259K *

Elevate your career by leading integrated optimization programs that enhance clinical, operational, and financial performance for healthcare clients. Drive measurable outcomes while managing diverse m...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.