Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$120K - $160K *

Advance HR technology by leading Workday administration, ensuring optimal system performance, security, and data governance. Collaborate with HR and IT to deliver solutions that enhance business proce...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$61K - $122K *

Transform clinical genetic curation by collaborating cross-functionally to enhance genomic testing, ensuring compliance with guidelines while supporting innovative health initiatives and improving pat...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$122K - $212K *

Unlock potential by leading global compensation strategies that enhance talent retention and recognition. Drive impactful programs, ensure compliance, and collaborate with senior leaders to align comp...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Advance your career by supervising nursing personnel and ensuring optimal patient care. Collaborate with various departments to enhance unit performance and participate in staff training and developme...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$184K - $396K *

Shape the future of healthcare technology by leading clinical informatics initiatives, enhancing patient outcomes, and driving enterprise-wide Epic optimization within a dynamic team of experts dedica...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$104K - $125K *

Advance patient care by providing direct clinical support, coordinating nursing activities, and ensuring high-quality standards. Supervise staff and manage resources effectively to enhance patient out...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $225K *

Lead the charge in architecting scalable technology solutions for institutional clients. Engage with cross-functional teams to create platforms that enhance client experiences, emphasizing technical d...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$88K - $90K *

Champion the development and implementation of individualized treatment plans for children, collaborating with a multi-disciplinary team to enhance early intervention services and ensure comprehensive...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Champion innovative radiology practices to enhance patient care and operational efficiency alongside a dynamic team. Drive clinical excellence and leverage technology to elevate standards across healt...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$204K - $306K *

Lead the charge in integrating AI with scientific workflows, mentoring engineers, and delivering innovative applications that enhance research collaboration. Drive technical strategy and foster a high...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$350K - $375K *

Lead the charge in defining and implementing a modern AI architecture across multiple business units, ensuring scalable, efficient, and secure AI systems that enhance product capabilities and drive in...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$155K - $259K *

Elevate your career by leading integrated optimization programs that enhance clinical, operational, and financial performance for healthcare clients. Drive measurable outcomes while managing diverse m...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$82K - $115K *

Transform the academic landscape by leading faculty development and student engagement. Drive excellence in teaching and support strategies while managing faculty performance and fostering a collabora...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$175K - $250K *

Drive medical leadership for early-phase clinical programs, focusing on innovative genetic therapies. Collaborate with cross-functional teams to ensure safety and efficacy in trials, while authoring k...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$174K - $218K *

Reimagine healthcare by shaping partnerships that drive innovative virtual-first care solutions. As a Senior Product Manager, you will bridge product and commercial teams, enhancing member engagement...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower healthcare technology by enhancing clinical systems and integrations. Collaborate with IT and business stakeholders to optimize workflows, manage projects, and ensure system performance across...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$150K - $200K *

Join a team that's shaping the future of self-funded health plans by drafting and negotiating critical contracts. Collaborate with cross-functional teams to ensure compliance and drive business succes...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $125K *

Pioneer impactful mental health services by leading, integrating, and overseeing comprehensive counseling operations that prioritize student success and well-being in a collaborative and equitable lea...

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $125K *

Provide strategic leadership and clinical oversight for comprehensive student counseling services, ensuring high-quality, culturally responsive support that enhances student well-being and success acr...

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$89K - $148K *

Innovate user experiences in robotic-assisted surgery by designing intuitive software interfaces. Collaborate with cross-functional teams to enhance Mako technologies, ensuring high-quality, accessibl...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$241K - $337K *

Transform your career with a flexible role in primary care, serving a diverse patient population. Collaborate with a dedicated team in a supportive environment, offering both part-time and full-time o...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $98K *

Join a team that's shaping the future of paid social strategy for top consumer brands. Drive growth through innovative, data-driven campaigns on platforms like Meta, TikTok, and YouTube, while mentori...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Accelerate program implementation and stakeholder engagement in pharmaceutical market access. Oversee daily operations, client relations, and staff management while ensuring adherence to budgets and p...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Transform healthcare through innovative AI deployments. As a key technical expert, you'll develop and implement cutting-edge systems that enhance clinical workflows and optimize patient interactions...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$299K *

Drive comprehensive patient care by joining a collaborative network of outpatient clinics, supported by hospitals and specialists, ensuring a seamless healthcare experience in a community-focused envi...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.