Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$138K - $201K *

Transform provider analytics by leading data-driven insights for contracting, performance, and network strategy. Collaborate with cross-functional teams to enhance network adequacy and drive strategic...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $190K *

Empower veterinary professionals by delivering expert dermatology advice and support, enhancing case management, and fostering strong relationships. Join a dynamic team committed to advancing veterina...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $167K *

Join us to analyze and optimize complex business processes, design ERP solutions, and lead integration efforts. Collaborate with teams to enhance performance and ensure compliance while delivering hig...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in optimizing procurement processes for federal contracts, ensuring compliance and efficiency. Collaborate with stakeholders to source, negotiate, and manage vendor relationships, driv...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$220K - $260K *

Elevate the buying experience by leading product strategy, enhancing catalog quality, and optimizing marketplace economics. Drive measurable outcomes through collaboration with operations and engineer...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$77K - $92K *

Join a dynamic team as a Medical Writer, where you'll interpret complex clinical protocols and create essential documentation for clinical studies, ensuring high-quality standards and regulatory compl...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $215K *

Join a team that's at the forefront of cyber investigations, leading a skilled pod to combat AI misuse. Drive complex attribution, mentor investigators, and enhance automated detection models while en...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$85K *

Innovate the future of asset protection by investigating theft and fraud, ensuring compliance, and safeguarding company resources through detailed analysis and collaboration with cross-functional team...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$83K - $110K *

Lead operational excellence by managing complex training programs and enhancing processes for a statewide initiative, ensuring effective communication and client engagement while fostering a high-perf...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Elevate market presence by driving adoption of innovative cardiac imaging solutions. Collaborate with healthcare professionals to enhance patient care, achieve sales targets, and optimize business str...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$210K - $256K *

Shape the future of consumer products, retail, and logistics consulting by leading high-impact transformation programs, building client relationships, and driving business growth through innovative st...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Information Technology

$210K - $256K *

Shape the future of consumer products and retail by driving large-scale transformations, cultivating executive relationships, identifying growth opportunities, and leading innovative initiatives in a...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Information Technology

$160K *

Shape the future of vertical marketing strategy by crafting tailored messaging that accelerates pipeline and drives revenue. Collaborate cross-functionally to embed insights and deliver impactful camp...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Accelerate your career by leading cross-functional programs that drive strategic initiatives in healthcare and biotechnology. Leverage your expertise to enhance product development, compliance, and op...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Join us to empower community coalitions in preventing youth substance use. As a Project Officer, you'll manage grants, provide technical assistance, and enhance local capacities, all while collaborati...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$94K - $151K *

Join a team that's shaping the future of insurance products by leading strategic initiatives, ensuring compliance, and driving market analysis. Collaborate with product managers to define vision and e...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $155K *

Lead the AI/ML product strategy across multiple business units, driving integration and data-centric solutions that enhance customer value and revenue growth through innovative workflows and collabora...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Elevate data privacy standards by leading a comprehensive privacy program. Collaborate across teams to integrate privacy-by-design principles, enhance data governance, and ensure compliance while enab...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$220K - $275K *

Elevate your career by leading global CMC regulatory strategies for biologics. Collaborate with cross-functional teams, ensure compliance, and drive successful product development while mentoring a hi...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$68K - $93K *

Unlock potential by driving sales through strategic customer engagement and relationship management. Utilize digital tools and territory management to enhance customer experiences and achieve sales ta...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $140K *

Drive your career forward by leading a dynamic PMO team, overseeing complex projects in healthcare technology. Collaborate cross-functionally to ensure strategic alignment and successful execution of...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $165K *

Elevate your career by driving strategic pricing initiatives and financial analysis. Collaborate cross-functionally to develop business cases, optimize pricing models, and present actionable insights...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Champion strategic growth by managing major law enforcement accounts, driving revenue, and fostering relationships with key stakeholders. Collaborate cross-functionally to ensure successful outcomes a...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$99K - $138K *

Help us streamline partner diligence and change management processes, ensuring compliance and operational efficiency. Collaborate across teams to enhance partner relationships and support their lendin...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$70K - $120K *

Lead transformative Medicaid initiatives by guiding project oversight, ensuring timely execution, and enhancing stakeholder engagement. Collaborate with teams to streamline operations and achieve stra...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.