Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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Sort By: Relevance

$100K - $120K *

Join a dynamic team leading materials management, overseeing purchasing and supply operations to enhance hospital performance and service quality while ensuring compliance with organizational goals an...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$189K - $199K *

Join a team that's redefining consumer relationships with food through innovative research. Drive impactful strategies and insights in a collaborative environment focused on behavior change and enhanc...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$78K - $83K *

Shape the future of audit excellence by developing innovative concepts, mentoring teams, and ensuring quality control. Drive client satisfaction and enhance audit productivity through strategic oversi...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by managing system design, build, and support for applications, ensuring optimal functionality and user satisfaction while collaborating across teams to enhance workflows and resolve...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $122K *

Take ownership of financial planning and analysis for G&A expenses, driving insights and reporting for senior leadership. Collaborate with teams to enhance budgeting, forecasting, and variance analysi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $195K *

Engage with healthcare payer clients to architect integrated solutions, driving revenue growth through strategic discovery, technical leadership, and value engineering. Collaborate across teams to del...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$138K - $191K *

Join a team that's redefining healthcare innovation by translating ideas into impactful solutions. Collaborate with senior executives to drive strategic initiatives and enhance population health throu...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Transform payment integrity operations by leading a dedicated team to enhance recovery processes, ensure compliance, and drive continuous improvement while achieving optimal performance and quality st...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Take ownership of corporate governance and entity management, ensuring compliance and efficiency across multiple subsidiaries. Support M&A and financing activities while maintaining a clean corporate...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$232K - $290K *

Shape the future of global People Operations by leading innovative HR service delivery, enhancing employee experiences, and driving operational excellence in a rapidly scaling biopharmaceutical enviro...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$105K - $124K *

Lead and optimize research intern activities, ensuring alignment with project goals and technical standards. Manage workflows, provide coaching, and conduct hands-on research while supporting the Dire...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$82K - $137K *

Transform business insights into actionable data solutions by collaborating with stakeholders, analyzing data quality, and ensuring effective integration of analytical products to drive operational ef...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$100K - $115K *

Grow your career with a dynamic team driving innovative strategies and customer engagement. Leverage your sales expertise to enhance product visibility and exceed business goals in a supportive, colla...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K *

Elevate sales strategies by owning the full sales cycle, building C-Suite relationships, and delivering impactful solutions to healthcare organizations across the Western US...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$221K - $335K *

Elevate clinical research by leading innovative studies, ensuring data integrity and patient safety. Collaborate cross-functionally to drive strategic initiatives and enhance clinical development whil...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $110K *

Champion compliance excellence by managing HR programs, ensuring alignment with laws, and enhancing processes. Collaborate across teams to minimize risk and support organizational growth while navigat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$90K - $110K *

Join a team that's dedicated to improving patient outcomes through comprehensive specialty care, managing both acute and chronic conditions while promoting health and well-being in collaboration with...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$137K - $205K *

Transform customer relationships by leading a team to enhance account management, drive product adoption, and ensure client success in the healthcare sector, fostering growth and retention across dive...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to managing diverse publications projects from start to finish. Collaborate with multidisciplinary teams, ensure client satisfaction, and maintain project budgets while dr...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$70K - $100K *

Join a team that's dedicated to optimizing Epic Resolute Professional Billing. Support daily operations, troubleshoot issues, and enhance workflows while collaborating with analysts and users to ensur...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$129K - $168K *

Optimize internal monitoring processes by leading clinical evaluations and audits across operational functions. Drive compliance, enhance decision-making, and foster team development to ensure alignme...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$70K - $105K *

Manage and oversee multiple medical communications projects, ensuring timely delivery and operational excellence while collaborating with cross-functional teams and clients to drive impactful healthca...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$58K - $125K *

Accelerate progress at the intersection of finance and strategy, driving cost accounting excellence and profitability analysis. Collaborate with cross-functional teams to enhance financial reporting a...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$220K - $260K *

Drive credit and fraud strategy for a lending business. Lead a high-performing team, manage risk and profitability, and partner with executives and stakeholders to achieve strategic objectives and dev...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$80K - $95K *

Drive customer support excellence by managing a frontline team to ensure timely resolutions, operational efficiency, and a culture of continuous improvement, paving the way for stellar service in heal...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.