Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$199K - $321K *

Explore a dynamic role shaping litigation and policy strategy in the pharmaceutical sector. Collaborate with senior leaders and external stakeholders to navigate complex legal landscapes, ensuring pat...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$113K - $208K *

Lead Oracle Fusion Field Service Cloud implementations, driving design, testing, and continuous alignment across teams. Collaborate with analysts and developers while ensuring effective project delive...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$140K - $187K *

Innovate the future of AI security by designing and implementing robust defenses against adversarial threats, ensuring the integrity of AI systems while fostering innovation and collaboration across c...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $140K *

Lead the charge in monitoring clinical study sites, ensuring data integrity and patient safety while collaborating with diverse teams to enhance study delivery and compliance with regulatory standards...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$146K - $224K *

Elevate clinical development by leading the strategy for biopharma platforms. Drive product lifecycles, collaborate with cross-functional teams, and ensure compliance while transforming workflows into...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$172K - $232K *

Lead the charge in advancing global quality initiatives, ensuring product excellence, and fostering expertise in quality risk management while collaborating across teams to enhance compliance and oper...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Manage dealer receivables by ensuring accurate accounting, reporting, and financial controls. Collaborate cross-functionally to enhance processes, drive automation, and maintain compliance while suppo...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$152K - $283K *

Accelerate analytics governance and operations by leading initiatives that enhance decision-making processes, streamline reporting, and modernize workflows across teams, ensuring effective collaborati...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's shaping the future of financial management in R&D. Drive project budgets, forecasts, and insights while collaborating with cross-functional teams to ensure financial efficiency and...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$94K - $107K *

Support and enhance data governance operations by collaborating with teams to implement standards, manage data cataloging, and drive tool adoption, ensuring compliance and effective governance workflo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$106K - $213K *

Transform the future of healthcare analytics by leading client engagements and delivering high-quality solutions. Collaborate across teams to ensure timely execution and drive operational excellence f...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$291K *

Engage with a dynamic team as a CRNA in a floating role, providing regional anesthesia across multiple facilities. Enjoy autonomy, diverse cases, and a supportive environment with competitive compensa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$106K - $122K *

Advance global immunization efforts by managing strategic partnerships and implementing evidence-based solutions to enhance vaccine demand and delivery in low and middle-income countries, focusing on...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$75K - $90K *

Transform financial insights into strategic initiatives, supporting planning and analysis as the organization scales. Collaborate across teams to enhance budget management, reporting, and performance...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$156K - $247K *

Lead the charge in patient engagement strategy, optimizing support programs and enhancing the patient journey from consideration to conversion. Collaborate across teams to amplify patient voices and d...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Develop and manage strategic customer relationships in the food, pharmaceutical, and personal care sectors, driving growth through high-quality ingredient solutions and exceptional service while lever...

4 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$99K - $136K *

Join a dynamic team as a strategic growth architect, driving revenue and market share expansion in the Hemostasis portfolio. Leverage your expertise in complex healthcare sales to influence decision-m...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$144K - $175K *

Drive impactful engagement with healthcare providers by promoting BMS medicines, fostering scientific dialogue, and enhancing customer experience in a field-based role focused on patient care and busi...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Innovate with us to enhance patient safety in global clinical studies. As a key medical expert, you'll provide critical input, oversee trial safety, and collaborate with teams to ensure compliance and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$228K - $342K *

Empower your career by leading strategic project management initiatives across early drug development. Drive process optimization, cultivate high-performing teams, and collaborate with executives to a...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Optimize the quality assurance process by leading data analytics and specification development. Drive actionable insights from complaints and non-conformance data while ensuring compliance across manu...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$80K - $110K *

Transform financial operations by providing analytical support, enhancing reporting processes, and collaborating with cross-functional teams to drive profitability and efficiency in budgeting and fore...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$81K *

Inspire excellence in nursing care by delivering compassionate, quality support to residents. Collaborate with a dedicated team to enhance the well-being of individuals in a nurturing environment, ens...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$118K - $236K *

Drive the product strategy for partner channel scheduling, collaborating with cross-functional teams to enhance user experience and operational efficiency in healthcare. Lead product development to en...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Engage in dynamic emergency medicine as an Advanced-Practice Provider, collaborating with a dedicated team to enhance patient care and well-being in a supportive, multi-specialty clinic environment...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.