Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$130K - $150K *

Advance innovative therapeutic programs targeting genetically driven diseases through strategic sourcing, relationship building, and cross-functional collaboration, ensuring a patient-first approach i...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $140K *

Pioneer GxP compliance in digital quality management, ensuring software and AI products meet regulatory standards. Collaborate with stakeholders to enhance quality processes and support audits, drivin...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $130K *

Drive program delivery across multiple products, ensuring timely outcomes by managing risks, dependencies, and stakeholder priorities. Collaborate cross-functionally to maintain accurate project data...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $220K *

Champion impactful scientific engagement by building relationships with key stakeholders, translating clinical data into actionable insights, and driving prelaunch strategies in a dynamic environment...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$72K - $120K *

Lead a multi-disciplinary team in developing machine learning algorithms to enhance clinical decision support, leveraging healthcare datasets for innovation and making vital discoveries that drive pro...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$325K - $447K *

Elevate medical affairs by providing strategic insights for clinical asset development and commercialization. Lead cross-functional teams, execute evidence generation plans, and foster collaboration t...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Champion demand generation by executing integrated campaigns to drive pipeline growth and revenue, collaborating cross-functionally with Sales and Product teams for fuel growth through strategic marke...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$124K - $170K *

Champion regulatory strategies to accelerate product approvals and compliance. Lead a dynamic team in supporting innovative medical devices, ensuring alignment with global regulations while fostering...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $180K *

Elevate healthcare creativity by leading innovative campaigns that transform client brands. Collaborate with teams to deliver impactful experiences across digital channels, leveraging insights and eme...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$169K - $282K *

Join a team that's redefining oncology clinical operations by leading a dynamic portfolio of studies. Drive excellence in delivery, manage complex projects, and mentor a talented team to ensure high-q...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $258K *

Join a dynamic team driving Master Data Management strategies to enhance data governance and operational efficiency across global orthopedic initiatives. Lead cross-functional collaboration to ensure...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$69K - $100K *

Optimize coding operations by leading a team to ensure compliance, accuracy, and efficiency in billing processes. Collaborate with stakeholders to enhance documentation quality and coding integrity wh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion quality control excellence by leading teams in Chemistry, Virology, and Immunochemistry. Ensure compliance with regulatory standards while driving process improvements and supporting cross-fu...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$81K - $122K *

Contribute to financial analysis and reporting, supporting strategic decision-making across departments. Collaborate with stakeholders to enhance budgeting, forecasting, and data management processes...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$85K - $105K *

Join a team that's dedicated to delivering impactful medical communications. As a Senior Account Manager, you'll lead strategic projects for pharmaceutical clients, ensuring quality and timely executi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $200K *

Unlock potential by driving sales strategies in the healthcare sector. Collaborate with C-Level executives, generate new opportunities, and enhance market presence while navigating complex enterprise...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $150K *

Drive success by building strong relationships with key customers, delivering strategic initiatives, and enhancing revenue growth. Collaborate across teams to identify opportunities and implement solu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform early phase clinical trials by leading design, execution, and oversight. Collaborate with cross-functional teams to ensure compliance and data integrity while managing project performance an...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$185K - $230K *

Elevate patient access by managing reimbursement strategies for rare diseases. Collaborate with healthcare providers and internal teams to ensure compliance and support patient journeys through comple...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $97K *

Shape the future of healthcare by conducting clinical case reviews and enhancing product quality for an AI-driven clinical platform. Collaborate with care teams to ensure accurate alert functionality...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Drive the execution of a comprehensive medical affairs plan for prostate cancer theranostics, collaborating across functions to enhance strategy, launch readiness, and lifecycle planning while advanci...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $162K *

Drive sales success in the Southern IL territory by developing strategic business plans, conducting impactful presentations, and fostering strong relationships with healthcare professionals to achieve...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Join a team that's dedicated to providing exceptional patient care through efficient admissions processes. As an Admissions Registered Nurse, you'll facilitate patient intake, collaborate with medical...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$170K - $190K *

Lead the charge in advancing analytical development strategies for small molecule drug substances and products, ensuring compliance and quality across the product lifecycle while collaborating with cr...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$146K - $178K *

Shape the future of biopharma by leading commercial strategy engagements, guiding clients through critical launch decisions, and delivering evidence-based recommendations to drive success in a dynamic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.