Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$295K - $325K *

Drive strategic sales leadership across the Western US, translating brand vision into effective field execution. Build and sustain a high-performing team while collaborating cross-functionally to achi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion safe patient care by optimizing pharmacotherapy within interdisciplinary teams. Conduct medication reviews and provide consults for various clinical areas, enhancing health outcomes through e...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to delivering exceptional pharmaceutical care across all patient ages. Collaborate with healthcare professionals to ensure optimal medication management while mentoring fu...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a dynamic team delivering patient care while supervising pharmacy staff. Champion operational excellence and contribute to cultural initiatives that drive success and sustainability in a complian...

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$134K - $249K *

Lead the charge in enhancing clinical systems operations, driving efficiency and effectiveness across pharmacy initiatives while managing a dedicated team and overseeing complex workflows and data int...

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Yesterday

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Engage with a talented team to drive growth and innovation in pharma sales. Own the sales cycle from strategic prospecting to closing high-impact deals, while developing key relationships that enhance...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in advancing enterprise automation capabilities, driving quality engineering innovation, and influencing strategic decisions across a rapidly growing organization, enhancing software r...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a dynamic pharmacy team to enhance operations and lead staff development. Drive quality, consistency, and continuous improvement while ensuring effective medication management and safety protocol...

Today

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in optimizing pharmacy operations, enhancing patient care, and driving team performance. Oversee compliance, manage budgets, and implement strategies for growth while ensuring exceptio...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$125K - $150K *

Transform supply chain operations by leading procurement, inventory management, and cash planning. Collaborate with cross-functional teams to ensure product delivery, regulatory compliance, and contin...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$195K - $244K *

Unlock your potential as a Global Regulatory Leader, driving regulatory strategy and submissions for CNS projects. Collaborate with cross-functional teams, mentor junior staff, and ensure compliance w...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$197K - $328K *

Shape the future of pharmacy network operations by leading a team of attorneys, providing strategic legal counsel on regulatory, operational, and transactional matters within the PBM landscape, while...

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Reposted 6 days ago

  •   8 - 10 years exp.  •   Healthcare

$189K - $246K *

Lead clinical pharmacology strategies, integrating PK/PD assessments across development phases. Collaborate with cross-functional teams to guide decision-making and regulatory submissions, ensuring al...

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Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $162K *

Drive pharmacy operations as a licensed Pharmacist, ensuring compliance, safety, and exceptional customer care. Lead a dedicated team while managing workflow, performance metrics, and process improvem...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$218K - $350K *

Shape the future of healthcare by leading our subscription business, driving growth and innovation. Collaborate across teams to enhance customer experience and optimize performance, ensuring alignment...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Champion the clinical supply chain for late-stage oncology trials, ensuring seamless operations and communication between sites, suppliers, and stakeholders. Drive continuous improvement and complianc...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's dedicated to excellence in inpatient pharmacy operations. Oversee 24-hour department functions, lead a skilled team, and drive quality care while achieving financial goals in a dyna...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead market expansion and provider relationships through consultative sales strategies, driving revenue growth and pipeline management within a dynamic healthcare environment while leveraging AI tools...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$119K - $186K *

Lead the development of a risk-based compliance framework for U.S. pharmaceutical commercialization, advising senior leaders and ensuring adherence to compliance standards while fostering ethical deci...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $238K *

Transform your career by leading the digital strategy for Medical Affairs. Drive innovation, optimize processes, and enhance scientific communications through emerging technologies while collaborating...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that's redefining oncology care by overseeing clinical standards, evaluating therapies, and engaging with providers. You'll play a key role in shaping patient eligibility and treatment pro...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $235K *

Join a team that's shaping the future of Medical Affairs by driving strategic client engagements and enhancing capabilities. This Director-level role balances client delivery and internal growth, focu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$127K - $159K *

Drive statistical leadership in oncology clinical development, guiding study design, analysis, and regulatory submissions. Collaborate with cross-functional teams to ensure high-quality deliverables a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$199K - $269K *

Shape patient affordability strategies by leading a dynamic team focused on co-pay programs and innovative solutions. Collaborate cross-functionally to enhance operations, optimize performance, and dr...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Unlock potential by driving data analysis and interpreting clinical trial results. Collaborate with stakeholders, ensure statistical integrity, and contribute to innovative methodologies in biostatist...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.