Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$130K - $176K *

Join a team that fosters mental wellness by diagnosing and treating patients with diverse psychiatric conditions. As a key member, you'll develop tailored treatment plans and promote effective medicat...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $131K *

Contribute to the development and administration of competitive compensation programs, ensuring alignment with organizational strategy. Lead projects and provide consultation to HR partners while main...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a team that's driving regional marketing initiatives in hematology and oncology. Engage with key thought leaders, execute strategic plans, and leverage local opportunities to enhance brand presen...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$199K - $276K *

Drive enhancements to our unsecured underwriting models through rigorous research and experimentation. Collaborate with engineering teams to translate findings into scalable solutions that improve cre...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$244K - $305K *

Drive financial strategy and analysis for global commercialization efforts, partnering with cross-functional teams to enhance decision-making and support successful product launches in the biopharmace...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$70K - $205K *

Solve complex challenges in MedTech and supply chain with a global team. Your expertise will drive transformative strategies, enhance client engagement, and support comprehensive project delivery in a...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Drive regulatory intelligence initiatives to ensure compliance and support clinical research. Collaborate with experts to assess regulatory changes, track global guidelines, and enhance impact assessm...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in managing interdisciplinary clinical research studies, ensuring compliance with GCP and regulatory requirements while driving project delivery, quality, and financial performance. Bu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$164K - $247K *

Join a dynamic team to lead central monitoring efforts in clinical trials, driving data-driven insights and risk management strategies. Collaborate across functions to enhance monitoring efficiency an...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$194K - $266K *

Champion patient engagement strategies by leading a dynamic team focused on optimizing recruitment and retention across clinical trials. Drive performance, enhance collaboration, and ensure successful...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$123K - $168K *

Engage with healthcare professionals to drive product growth and acceptance. Build lasting relationships, educate stakeholders, and collaborate cross-functionally to enhance market presence and uphold...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$114K - $187K *

Optimize clinical data management processes by leading teams and ensuring compliance with standards. Collaborate with stakeholders to enhance data quality and streamline operations across multiple com...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $187K *

Explore a rewarding role providing in-home health evaluations, fostering relationships to enhance patient care. Travel extensively to deliver personalized health services, ensuring comprehensive suppo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $240K *

Lead strategic relationships with influential optometrists and ophthalmologists, shaping the Presbyopia ecosystem through education and engagement. Drive insights and collaboration across medical, mar...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $185K *

Champion strategic payer engagement to enhance access and reimbursement across a national portfolio. Drive medical policy influence and build relationships with key stakeholders to expand coverage and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$240K - $330K *

Lead the development of patient experience strategies, integrating insights and design thinking to enhance patient journeys across therapeutic areas. Collaborate with cross-functional teams to drive i...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $105K *

Join a dynamic team to coordinate supplier management, drive contract workflows, and ensure compliance in clinical studies. Collaborate with cross-functional teams to enhance supplier processes and su...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$80K - $100K *

Advance impactful medical communications by crafting precise, engaging content. Collaborate with cross-functional teams to ensure accuracy and alignment with client objectives while mentoring junior s...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Empower patient care by providing comprehensive services to individuals of all ages. Collaborate with a dedicated team while working independently to enhance community health and well-being in a suppo...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $250K *

Join a dynamic team to enhance patient care by promoting innovative oncology solutions, educating healthcare providers, and driving strategic account management to elevate brand presence and improve p...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $201K *

Join a dynamic team to drive clinical trials, ensuring compliance and quality. Manage site relationships, monitor trial progress, and collaborate with cross-functional teams to deliver innovative ther...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$74K - $98K *

Elevate quality operations by leading corrective action plans (CAPs) for regulatory compliance. Collaborate with cross-functional teams to drive accountability, resolve barriers, and ensure sustained...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$99K - $136K *

Transform supplier relationships and drive category growth through strategic marketing, sales analysis, and new product launches. Lead initiatives to enhance profitability and market share while colla...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $149K *

Advance the organization by establishing robust data and AI governance practices. Collaborate across teams to ensure compliance, integrity, and responsible usage of data and AI assets, supporting both...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $300K *

Build strategic relationships with scientific leaders to drive innovation in Pulmonary Hypertension. Engage in scientific exchange, support research initiatives, and enhance understanding of therapeut...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.