Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$210K *

Empower patients by delivering high-quality telehealth services across Iowa. Manage diverse clinical cases through virtual consultations, ensuring compassionate care while enjoying a flexible schedule...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$83K - $222K *

Transform data engineering practices by designing robust data pipelines and models. Collaborate with cross-functional teams to enhance analytics capabilities and ensure data quality, governance, and p...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in managing clinical operations for dialysis services, ensuring quality patient care, compliance, and operational efficiency across multiple facilities while fostering strong relations...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$235K - $270K *

Unlock your potential as a strategic leader in field medical operations, driving scientific exchange and enhancing patient identification. Collaborate with key opinion leaders while building scalable...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$119K - $186K *

Advance your career by providing strategic legal counsel on data governance, privacy, and cybersecurity within a dynamic healthcare environment. Collaborate with cross-functional teams to drive compli...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Lead the evaluation of outpatient referrals and inpatient admissions for medical necessity, utilizing guidelines and criteria to ensure quality care. Collaborate with providers and mentor UM nurses to...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$85K - $105K *

Shape impactful insights through analytics, driving data-informed decisions for healthcare clients. Collaborate with cross-functional teams to enhance marketing performance and audience understanding...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Empower innovation in clinical trials by developing strategies, overseeing operations, and cultivating partnerships. Drive excellence in research, enhance compliance, and manage a high-performing team...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$138K - $183K *

Lead the development and execution of patient support strategies to enhance access and engagement for oncology therapies, collaborating cross-functionally to optimize promotional initiatives and drive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$132K - $153K *

Join a team that's redefining care management by leading strategic initiatives in utilization and appeals processes. Drive high-quality, cost-effective care while ensuring compliance and fostering a c...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$197K - $246K *

Lead strategic initiatives in market access by managing key payer accounts, ensuring optimal coverage and reimbursement for products. Collaborate with cross-functional teams to enhance patient access...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate your career by leading innovative packaging design strategies that resonate globally. Collaborate with cross-functional teams to create compelling visuals while ensuring brand consistency and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $230K *

Join a team that's transforming oncology care by promoting innovative treatments and building strong relationships with healthcare professionals. Drive brand value and ensure patient access while lead...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a dynamic team to leverage your scientific expertise in enzymes and animal nutrition. Collaborate across departments to design trials, solve customer challenges, and drive product innovation whil...

2 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $140K *

Reimagine client success by managing relationships and ensuring seamless communication across teams. Drive operational excellence and enhance client satisfaction through proactive updates, coordinatio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $160K *

Drive the Order-to-Cash strategy, overseeing cash application, collections, and AR performance. Collaborate cross-functionally to optimize cash flow and enhance financial reporting, ensuring timely re...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join a team that's redefining healthcare recruiting by building and scaling a high-impact Direct Employer business through innovative sales strategies and cutting-edge technology, driving growth direc...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Staffing

$228K - $342K *

Advance the future of R&D governance and portfolio management by leading strategic decision-making processes, optimizing operational efficiency, and ensuring seamless progression of therapeutic assets...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Unlock regional growth by leading a high-performing sales team, executing launch strategies, and fostering key customer relationships in a dynamic, fast-paced environment. Drive performance and ensure...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Join a team that's dedicated to transforming complex scientific data into clear, impactful content. Collaborate with peers to ensure accuracy and adherence to guidelines while developing crucial mater...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $88K *

Drive financial stewardship and risk management by supporting the Finance Manager in enhancing financial systems and processes, ensuring compliance, and delivering effective solutions for humanitarian...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Transform the communications landscape by building a dynamic team that drives brand relevance through strategic earned media, influencer relations, and corporate communications, ensuring a consumer-fi...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $85K *

Grow your career with a dynamic team focused on client success, managing relationships, and delivering tailored solutions. Drive satisfaction and retention while collaborating across departments to en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Empower cross-functional teams to drive the Future of Medicine initiatives, ensuring scalable processes and compliance while enhancing patient safety and experience through strategic planning and exec...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$68K - $113K *

Lead the charge in optimizing coding accuracy and compliance by analyzing complex patient care documentation, providing expert guidance, and enhancing coder education to ensure adherence to ethical st...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.