Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$190K - $228K *

Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by delivering impactful leadership and soft skills training for pharmaceutical and life sciences professionals. Engage diverse audiences, foster collaboration, and drive behavior chan...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Empower the execution of CMC strategies by collaborating across teams to enhance production, streamline operations, and drive commercial success for innovative therapeutics and diagnostics, ensuring a...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in developing and executing channel strategies to drive growth, onboard high-performing partners, and enhance relationships with distributors in the life sciences sector...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$175K - $219K *

Optimize medical sponsorship strategies and operations by collaborating with stakeholders, managing budgets, and ensuring timely execution of congress activities while enhancing process efficiency and...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$174K - $374K *

Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$250K - $350K *

Lead the development of a clinical supply consulting practice, combining expertise in forecasting, planning, and optimization to enhance decision-making for sponsors. Drive innovation and commercial g...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $170K *

Shape the future of healthcare market strategies by analyzing trends, defining growth initiatives, and collaborating cross-functionally to drive innovation in life science and medical services. Lead m...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$267K - $331K *

Join a dynamic team as a senior leader in pharmaceutical development, driving CMC strategy and cross-functional collaboration. Lead high-performing teams, influence corporate strategy, and ensure alig...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Shape the future of oncology by driving product success and building strong relationships with healthcare professionals. Lead initiatives that enhance patient access and deliver innovative solutions i...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Champion supply chain strategy and execution for clinical operations, ensuring timely, compliant delivery of materials for global oncology trials. Collaborate with cross-functional teams to manage ris...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Drive growth and strategy for key telehealth categories by leveraging market insights, customer feedback, and cross-functional collaboration to enhance performance and deliver exceptional customer exp...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Shape the future of oncology by leading biologics process development and manufacturing. Collaborate across teams to ensure compliance and quality in clinical-stage products, while mentoring scientist...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$82K - $182K *

Analyze healthcare costs and quality outcomes to drive value-based care strategies, collaborating with clinical and financial teams. Lead data-driven insights and financial modeling to enhance operati...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $200K *

Elevate your career by driving sales strategy and execution for a dynamic SaaS portfolio. Lead a high-performing team to achieve revenue growth, optimize pipeline management, and enhance customer acqu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$85K - $100K *

Join a team that's focused on driving financial accuracy while managing month-end closes, reconciliations, and cost accounting. Contribute to board-level reporting in a dynamic PE-backed SaaS environm...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$208K - $250K *

Engage with residents as a trusted Physician, delivering high-quality, person-centered care in skilled nursing facilities. Mentor APPs, improve health outcomes, and enjoy the autonomy of private pract...

Today

  •   Less than 5 years exp.  •   Healthcare

$150K - $230K *

Manage strategic oncology product promotion and build relationships with key stakeholders. Drive performance goals, analyze market data, and ensure patient access to therapies while embodying corporat...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$177K - $221K *

Lead the development and execution of global CMC regulatory strategies to support clinical trials and market applications, ensuring compliance with regulatory requirements throughout the product lifec...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$143K - $194K *

Join a team that drives the execution of integrated media plans, ensuring compliance and operational excellence. Collaborate with cross-functional teams while enhancing brand strategies in healthcare...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $220K *

Drive product strategy and development to enhance clinician experience, optimizing patient care through innovative solutions and stakeholder collaboration across a nationwide healthcare network...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$72K - $108K *

Transform your career by developing strategic sales plans and building strong relationships in a dynamic territory. Drive results through effective presentations and ethical practices while achieving...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Transform the future of oncology care by driving product success and building strong relationships with key stakeholders. Lead initiatives that enhance patient access and deliver innovative solutions...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$141K - $191K *

Champion high-impact scientific communication strategies, collaborating across Medical Affairs and Commercial. Lead content development, enhance engagement, and drive operational excellence for effect...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$61K - $102K *

Lead a dynamic team to optimize hospital operations, enhance service quality, and ensure compliance. Drive performance improvements and foster strong partnerships while managing logistics and inventor...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.