Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$150K - $165K *

Build and manage clinical stewardship operations, driving client success through effective program implementation and cross-functional collaboration. Leverage clinical expertise to enhance client rela...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's driving innovative marketing strategies to enhance brand growth and engagement. You'll lead a small team, manage multi-channel campaigns, and collaborate with operations to elevate...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$135K - $145K *

Partner with us to elevate healthcare communications by crafting compelling copy for HCP campaigns. Lead creative initiatives, collaborate with cross-functional teams, and ensure brand consistency acr...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$78K - $156K *

Join a team that's dedicated to enhancing business systems through design, configuration, and support. As a Senior Application Analyst, you'll lead improvements, mentor junior analysts, and ensure sea...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $158K *

Optimize financial performance by partnering with operations to enhance cost efficiency and profitability. Drive strategic investment decisions and support budgeting processes while ensuring alignment...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$176K - $287K *

Contribute to companion diagnostic strategy and development, leading programs from biomarker feasibility to clinical validation. Collaborate across teams to ensure diagnostics align with therapeutic m...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Unlock potential by enhancing urology patient evaluations and care. This role focuses on outpatient assessments, patient follow-ups, and adherence to safety standards, ensuring high-quality service in...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Drive financial accuracy and compliance as a Senior Accountant. Lead month-end close, maintain internal controls, and support auditors while refining processes. Ideal for proactive self-starters seeki...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$245K - $265K *

Shape the future of neurology by building partnerships with Medical Experts, driving insights, and collaborating across teams to enhance patient care and strategic initiatives in a dynamic healthcare...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$131K - $176K *

Oversee global Contract Manufacturing partnerships, driving productivity and ensuring quality goals are met. Collaborate cross-functionally to support new product launches and process improvements, wh...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K *

Drive new business growth by owning the full sales cycle in SMB and Mid-Market segments. Build relationships, strategize territory plans, and deliver compelling proposals to meet client needs while ex...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $165K *

Elevate your career as a Scientific Product Owner, driving innovation in clinical genomics software. Collaborate with cross-functional teams to translate scientific needs into actionable requirements...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$63K - $101K *

Optimize compliance in Interventional Radiology charge capture by conducting audits, educating teams, and enhancing coding practices. Collaborate with clinical departments to identify and rectify codi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$236K - $354K *

Elevate clinical operations by leading global study management, driving strategic vision, and ensuring high-quality trial execution. Collaborate across teams to optimize resources and foster a culture...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Join our dynamic team to develop innovative sourcing strategies, lead supplier negotiations, and drive value creation within the Americas, contributing significantly to our growth and sustainability g...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Join us to manage a defined territory, building partnerships with oncology teams. Develop strategic plans to enhance patient access and drive results, collaborating with cross-functional teams to addr...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to enhancing patient access in oncology. Manage a defined territory, build partnerships with care teams, and drive impactful results through strategic planning and collabo...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape the future of cybersecurity analytics! As a crucial member of the AI & Data team, you will develop data ontologies, build machine learning models, and analyze cyber data, collaborating with dive...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$120K - $150K *

Champion integrated project management for complex pharmaceutical advertising, leading cross-functional teams to ensure timely delivery within scope and budget while mentoring junior staff and enhanci...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to enhancing client relationships and driving success. Oversee client performance, mentor staff, and ensure compliance while collaborating with various departments to deli...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $130K *

Partner with us to drive product innovation and marketing strategies across dietary supplements and topical hair care. Collaborate with cross-functional teams to launch new products, ensuring alignmen...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$168K - $231K *

Drive transformation by partnering with cross-functional teams to design and implement effective product operations, ensuring alignment with strategic goals and enhancing organizational effectiveness...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$145K - $155K *

Join a team that's dedicated to providing virtual behavioral health services to military personnel. Utilize your expertise in clinical psychology to deliver evidence-based treatments and support patie...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$143K - $193K *

Transform clinical operations by leading regional study delivery, ensuring quality and compliance while managing timelines and budgets. Collaborate with cross-functional teams to drive study success a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$117K - $160K *

Champion profitable growth by managing E&S commercial property and casualty underwriting. Leverage strong technical skills and relationships to assess risks, deliver competitive quotes, and optimize p...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.