Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$80K - $95K *

Transform credentialing operations by leading a dedicated team to ensure compliance, enhance efficiency, and support provider network growth through strategic oversight and process improvement initiat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Lead the charge in ensuring compliance and integrity within federal healthcare programs through rigorous investigations, data analysis, and collaboration with key stakeholders to produce actionable fi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$140K - $170K *

Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$67K - $111K *

Elevate your career by providing critical analysis and programming support for application software, ensuring a comprehensive and integrated information network that meets diverse customer needs and e...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Join a team that's transforming medicine by engaging with KOLs and healthcare professionals. Leverage your clinical expertise to communicate product benefits, support education, and drive strategic in...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$174K - $234K *

Shape the future of advanced analytics and AI, driving data-driven solutions across commercial, medical, and clinical operations. Collaborate cross-functionally to deliver insights, enhance decision-m...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$164K - $225K *

Develop and execute patient advocacy strategies, engaging with PAOs and cross-functional teams to elevate the patient voice and ensure successful partnerships for rare disease therapeutic areas...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $215K *

Shape the future of value-based payments by leading product strategy, overseeing team development, and driving market innovations within a collaborative, cross-functional environment...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$225K - $265K *

Transform healthcare interoperability by leading product strategy and market growth. Leverage deep industry insights to enhance payer-provider collaboration, drive operational excellence, and oversee...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$146K - $225K *

Manage compliance for the Affirm Card program, ensuring regulatory adherence across marketing, onboarding, and servicing. Collaborate with cross-functional teams to navigate complex compliance challen...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's advancing biomaterial research for medical devices. Drive experimental trials, support GMP manufacturing, and ensure quality compliance while collaborating with cross-functional tea...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $110K *

Transform clinical data into engaging scientific content with growth opportunities. Collaborate, communicate, and adhere to guidelines in a dynamic environment, supporting varied projects across forma...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$185K - $230K *

Shape the future of patient access by leading reimbursement strategies and support for rare disease therapies. Collaborate cross-functionally to enhance provider education and patient understanding, e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $250K *

Transform operations by leading a diverse team to enhance profitability and efficiency across multiple sites, while building strategic relationships with clients and driving growth initiatives in the...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $225K *

Shape the future of consumer experiences by leading product strategy, driving measurable outcomes, and collaborating with cross-functional teams to enhance member satisfaction throughout their shoppin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$85K - $100K *

Lead the charge in delivering comprehensive medical care and support to patients, ensuring continuity and quality in managed care while collaborating with a dedicated medical team to enhance pediatric...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$62K - $97K *

Join a dynamic team as you manage cloud-based marketing tools, ensuring optimal performance and user adoption. Collaborate across departments to implement solutions that drive business success and enh...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by delivering comprehensive health assessments in patients' homes. This role requires extensive travel within a region, ensuring quality care and education while collaborating with he...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Drive comprehensive health assessments by traveling to patients' homes, ensuring accurate documentation and patient education. Collaborate with healthcare teams to enhance care continuity while managi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join our Clinical Science team to enhance data integrity in CNS trials by conducting meticulous reviews of clinical interviews, ensuring protocol compliance, and guiding site interventions as a Clinic...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Manage your career with a pivotal role blending clinical care and leadership. Drive operational success while mentoring providers and enhancing patient experiences in a dynamic healthcare environment...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$274K - $371K *

Develop and lead early phase clinical strategies for oncology candidates, ensuring design and execution of clinical trials. Collaborate with internal teams and external experts to drive innovative dru...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform health information management by leading end-to-end processes, ensuring compliance, and optimizing workflows. Collaborate across departments to enhance operational performance and support or...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$89K - $155K *

Lead the charge in connecting with medical professionals, delivering clinical insights, and driving product utilization while navigating complex payer environments to enhance patient care and achieve...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $122K *

Unlock your potential as you lead financial planning, analytics, and strategic initiatives. Collaborate closely with executives to drive performance improvements and optimize resource allocation, fost...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.