Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$125K - $150K *

Accelerate your career by leading innovative marketing strategies that drive lead generation and revenue growth. Collaborate with cross-functional teams to enhance brand visibility and cultivate a cul...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$168K - $210K *

Transform pricing strategies by leading cross-functional teams to enhance decision-making and model deployment. Drive the evolution of pricing platforms, integrating advanced AI to streamline workflow...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $110K *

Unlock potential by leading the functional support and improvement of business systems for Legal, Procurement, Safety, and Environmental teams, ensuring effective use and resolution of issues while en...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $100K *

Transform software delivery by managing cross-functional teams, aligning sprints, and optimizing project timelines. Drive clarity in processes and foster collaboration to ensure successful product exe...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$113K - $125K *

Drive product strategy and outcomes in a senior role, focusing on educational equity and data-driven impact. Collaborate with cross-functional teams to shape product direction, prioritize initiatives...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$117K - $130K *

Transform your career by leading strategic go-to-market initiatives for a fast-growing ELA Core Curriculum portfolio. Drive impactful messaging, cross-functional alignment, and scalable processes to e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead the strategy and development of digital publishing products, enhancing workflows and user experiences. Collaborate across teams to create a cohesive ecosystem that supports efficient content mana...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $120K *

Shape the future of marketing strategy for a premier industry expo, driving attendance and engagement through innovative campaigns and cross-functional collaboration. Lead a dynamic team to enhance br...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$160K - $210K *

Join a dynamic team to shape financial systems that drive growth and innovation. You'll own the strategy for money movement and banking, collaborating across departments to enhance reliability and sca...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$114K - $158K *

Drive financial excellence by leading integrated management of Technology spend, enhancing visibility, and optimizing costs through collaboration with cross-functional teams to improve processes and d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$102K - $184K *

Unlock potential by leading high-impact engagements in digital assets, guiding clients through evolving risks and regulatory landscapes while enhancing internal controls and operational strategies in...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$190K - $283K *

Drive impactful data analyses and innovative experiment design to enhance product strategies and optimize Ads Marketplace performance, collaborating with cross-functional teams in a flexible, hybrid w...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$160K - $180K *

Design and execute innovative product strategies for digital image exchange, ensuring seamless healthcare workflows and market differentiation. Collaborate with cross-functional teams to enhance enter...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$132K - $166K *

Unlock financial insights at a strategic level, driving value realization and governance for transformation investments. Collaborate across functions to enhance performance, support decision-making, a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$103K - $123K *

Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Lead the charge in optimizing marketing operations to drive developer adoption, pipeline growth, and revenue. Oversee systems, processes, and insights while collaborating with cross-functional teams t...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$105K - $135K *

Champion user engagement by designing and executing lifecycle marketing strategies. Drive retention and conversion through targeted campaigns, leveraging data insights and creative messaging to enhanc...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$180K - $252K *

Shape the future of advertising on a leading platform by designing intuitive tools and experiences that empower businesses while enhancing user engagement and trust within the community...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Media

$110K - $172K *

Shape global procurement governance and compliance by leading analytics, training, and process excellence initiatives. Drive transformation and data management in a collaborative environment to enhanc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$160K - $280K *

Lead the charge in architecting and optimizing our web platform and AI agents, ensuring seamless integration for marketing use cases. Drive technical decisions and empower marketers with tools to inno...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$152K - $259K *

Drive impactful product decisions by leading a high-performing Data Science team. Set strategic goals, prioritize initiatives, and foster a culture of accountability while collaborating with Product a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $220K *

Lead the charge in defining and delivering innovative data products for Trust & Safety, ensuring AI models are trained safely and effectively through advanced reinforcement learning environments and r...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Drive and support deal structuring for a commercial portfolio, collaborating with sales to close strategic opportunities. Manage proposals, objection handling, and internal approvals while enhancing c...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$133K - $200K *

Accelerate clinical data management processes by leading data entry, ensuring quality, and overseeing database development for clinical trials. Collaborate with cross-functional teams to meet project...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$133K - $200K *

Drive excellence in clinical data management by overseeing data processes, ensuring quality, and leading cross-functional teams to deliver timely and accurate results throughout the clinical trial lif...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.