Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
$100K - $140K *
Optimize client relationships by ensuring seamless communication and operational excellence. Collaborate across teams to drive client success, manage deliverables, and enhance platform utilization whi...
2 weeks ago
$82K - $132K *
Unlock potential in revenue cycle management by leading innovative solutions, optimizing processes, and collaborating across departments to enhance operational efficiency and maximize revenue impact...
Yesterday
Operations Manager - Occupational Health & Wellness Clinics
$90K - $110K *
Transform workplace health by leading multiple occupational health clinics. Drive operational excellence, foster client relationships, and enhance team performance while ensuring exceptional patient c...
1 week ago
$125K - $150K *
Empower legal firms by leading the development of innovative IT solutions, driving market strategies, and enhancing service offerings. Collaborate with cross-functional teams to establish credibility...
1 week ago
Surgery Imaging Field Engineer 1
$66K - $99K *
Join a team that's dedicated to delivering world-class customer service by providing technical support for GEHC Surgery equipment. Collaborate with field engineers to enhance customer satisfaction and...
Today
Manager, AI & Workflow Operations - Licensed (RN, NP, PA, or MD, RPh, PharmD)
$100K - $120K *
Transform healthcare delivery by leading operations for a growing telehealth practice. Collaborate with clinical teams to enhance patient care through innovative solutions and efficient workflows, ens...
1 week ago
$150K - $215K *
Lead the charge in driving enterprise sales for strategic consulting accounts, coaching a team of Account Executives while managing complex sales cycles. Build executive relationships and execute grow...
2 weeks ago
$115K - $130K *
Drive rapid service restoration by leading IT incident management processes, ensuring effective communication and coordination for critical incidents. Leverage expertise in troubleshooting and support...
Reposted 3 weeks ago
Principal AI Transformation Consultant, Professional Services
$100K - $185K *
Transform complex workflows by leading AI-driven change initiatives, guiding senior leaders through redesign and adoption processes, and ensuring measurable outcomes in legal, tax, and trade sectors...
2 weeks ago
Staff Engineer, Security Operations
$225K - $281K *
Lead detection and response strategy, building systems and automations to enhance security. Collaborate with teams to set standards, mentor engineers, and manage complex incidents, ensuring effective...
1 week ago
Physician Relations Team Manager
$106K - $167K *
Shape the future of physician relations by leading a dynamic team focused on enhancing patient acquisition and optimizing outreach strategies through data-driven insights and performance metrics...
2 days ago
Client Growth & Success, Senior Manager- Enterprise Accounts
$130K - $145K *
Champion client success by managing strategic partnerships with mid-sized enterprises. Drive measurable outcomes through relationship management, consultative problem-solving, and cross-functional col...
2 weeks ago
$75K - $100K *
Innovate user experiences by managing and enhancing the Salesforce platform. Collaborate with stakeholders to translate business needs into effective solutions, ensuring data quality and user adoption...
3 days ago
$135K - $160K *
Empower strategic growth by developing and executing multi-year partner strategies. Collaborate with sales and executive teams to enhance alliances, drive revenue, and foster innovation across North A...
1 week ago
Account Specialist (San Jose, CA)
$160K - $192K *
Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...
1 week ago
Staff/Principal AI Scientist - Virtual Tissue
$150K - $180K *
Engineer advanced protein design models and collaborate with experts to innovate in AI Drug Discovery, driving the development of candidate antibody therapeutics through deep learning and systems biol...
Reposted 1 week ago
Therapy Development Specialist - Northeast Region
$110K - $175K *
Accelerate patient care by optimizing therapy pathways and engaging key stakeholders. Collaborate with healthcare teams to enhance VTE awareness and program development, driving clinical initiatives a...
1 week ago
$115K - $158K *
Shape the future of healthcare by leading the Organic Risk Adjustment program. Drive strategic initiatives, foster collaboration across teams, and implement innovative solutions to enhance performance...
3 days ago
$160K - $180K *
Empower commercial operations by leading a dynamic Deal Desk team, driving strategy, optimizing processes, and executing complex transactions in a fast-paced SaaS environment. Collaborate cross-functi...
1 week ago
$125K - $150K *
Drive enterprise growth by strategically engaging high-value accounts, orchestrating complex sales processes, and leveraging AI capabilities to enhance compliance workflows. Build executive relationsh...
Yesterday
$100K - $120K *
Drive operational excellence by leading Hub programs, enhancing performance metrics, and developing Supervisors. Collaborate cross-functionally to ensure effective service delivery and continuous impr...
2 days ago
Acute Dialysis Registered Nurse, RN
$104K - $108K *
Transform patient care by delivering high-quality acute dialysis services. Collaborate with healthcare teams to ensure optimal outcomes through assessment, planning, and implementation of individualiz...
Yesterday
$138K - $180K *
Empower the GTM organization by leading full-cycle recruiting for mid and senior-level sales roles. Collaborate with hiring managers, build diverse pipelines, and leverage data to enhance hiring strat...
1 week ago
$116K - $167K *
Lead the successful delivery of complex projects, managing resources and stakeholders while ensuring adherence to budget, schedule, and quality standards. Empower teams through mentorship and expert g...
3 weeks ago
$90K - $110K *
Analyze clinical documentation and risk adjustment for healthcare providers, ensuring accurate representation of patient acuity. Collaborate with physicians to identify documentation opportunities and...
4 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.