Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Oncologist Jobs in Iowa

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$91K - $115K *

Transform the candidate experience by sourcing top talent for sales and corporate roles. Collaborate with recruiters and hiring managers to build pipelines, utilizing advanced sourcing techniques and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Elevate customer relationships by managing and growing strategic national accounts. Focus on retention, upselling, and cross-selling within the Collision and Mechanical sectors while leveraging SaaS s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$170K - $205K *

Accelerate business growth by driving sales strategies and building key relationships in the healthcare sector. This role requires expertise in navigating complex environments and a commitment to achi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$102K - $182K *

Lead the design and delivery of innovative clinical sales training programs for Structural Heart, enhancing sales team effectiveness and product knowledge through strategic curriculum development and...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $175K *

Accelerate growth through strategic demand generation and integrated marketing campaigns. Collaborate with Sales and Product teams to optimize the pipeline, drive revenue, and enhance customer engagem...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $165K *

Join us to drive the launch of a pioneering biotech product, enhancing healthcare provider engagement and patient outcomes across your territory while achieving sales targets in a dynamic, fast-paced...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $170K *

Champion growth by engaging complex life sciences accounts, driving value through strategic relationships. Navigate multifaceted deals with precision, collaborating across teams for impactful sales su...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$122K *

Champion project success by leading interdisciplinary teams to deliver innovative solutions in the biotech and pharma sectors. Drive milestone achievement, manage budgets, and ensure compliance with p...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive innovative technology solutions that enhance operational performance, ensuring secure and reliable infrastructure. Collaborate with cross-functional teams to lead projects, manage budgets, and a...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$170K - $205K *

Accelerate progress at driving U.S. sales strategy for a new kidney transplant product. This role requires strategic account management, cross-functional collaboration, and a focus on building relatio...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Lead the charge in delivering strategic and operational excellence across high-profile medical affairs accounts, fostering client relationships and guiding teams to achieve exceptional results in publ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the SAP Analytics strategy and implementation, driving innovation in analytics solutions. Collaborate with stakeholders to deliver insights and manage teams, ensuring successful deployment of SAP...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$74K - $98K *

Champion regulatory audit excellence by leading PACE audits, ensuring compliance, and driving cross-functional collaboration to enhance operational readiness and continuous improvement across the orga...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Drive operational excellence by leading a global team to deliver high-quality wellbeing programs. Collaborate with stakeholders to ensure effective execution, maintain standards, and enhance participa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $194K *

Champion the standardization of financial posting logic across Oracle EBS, ensuring compliance and audit readiness. Collaborate with cross-functional teams to enhance federal financial processes and s...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Unlock potential by leading enterprise sales initiatives, managing complex accounts, and driving strategic growth. You will navigate technical discussions and deliver value-driven solutions to top-tie...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$69K - $125K *

Transform regulatory insights into actionable strategies by analyzing national and state legislative activities. Collaborate with legal and business teams to ensure compliance and support effective de...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team as you manage clinical research sites, ensuring compliance and quality throughout all study phases. Build strong relationships, oversee monitoring activities, and contribute to tea...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive impactful projects by collaborating across teams to enhance operational efficiency and deliver innovative solutions. Leverage your expertise to influence strategic decisions and contribute to a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$199K - $235K *

Innovate backend solutions by designing, building, and maintaining scalable services for external pentesting. Collaborate across teams to enhance user experience and ensure system performance, reliabi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Shape the future of patient care by leading Interventional Radiology operations. Oversee clinical management, enhance patient satisfaction, and drive financial performance while collaborating with mul...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Lead strategies to drive environmental due diligence growth, manage key client relationships, oversee project execution, and ensure delivery of high-quality results through effective team leadership a...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$162K - $195K *

Take ownership of driving sales performance in your territory by launching a novel cardiac myosin inhibitor. Collaborate with internal teams and external stakeholders to build strategic relationships...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$94K - $164K *

Empower your career by managing a profitable middle-market construction book. Leverage your E&S underwriting expertise to build relationships, identify opportunities, and drive growth with minimal sup...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in managing complex projects within the pharmaceutical and biotech sectors, ensuring successful execution and delivery while mentoring teams and collaborating with stakeholders to achi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.