Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Oncologist Jobs in Iowa

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$95K - $115K *

Join a team that's dedicated to providing exceptional pharmaceutical care in acute settings. As a Clinical Pharmacist, you'll collaborate with healthcare professionals to ensure safe medication practi...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $268K *

Drive state and local government relations across 25 states, managing legislative efforts and stakeholder engagement to advance business goals. Collaborate with internal teams and external partners to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $205K *

Join a team that's driving sales strategy for a new kidney transplant product. Leverage your expertise in account management and cross-functional collaboration to establish a strong market presence an...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in managing litigated claims, evaluating liability, and negotiating settlements. Collaborate with teams to enhance processes while ensuring compliance and maintaining strong relationsh...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Lead a dedicated team in the Emergency Department and ICU, driving clinical excellence and patient safety. Collaborate with physicians and staff to enhance care quality and outcomes, making a signific...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $115K *

Unlock potential by leading requirements documentation for software projects. Collaborate with stakeholders and technical teams to ensure successful delivery throughout the project lifecycle, while su...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$92K - $120K *

Join a team that's dedicated to enhancing sales performance through innovative training. You'll design and deliver engaging learning experiences, collaborate with sales leaders, and leverage AI tools...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$199K - $276K *

Drive enhancements to our unsecured underwriting models through rigorous research and experimentation. Collaborate with engineering teams to translate findings into scalable solutions that improve cre...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $192K *

Engage healthcare providers and drive commercial performance in a defined territory. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative therapi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive transformative philanthropy across a leading health care enterprise, overseeing fundraising strategies and managing a high-performing team to enhance patient care and community engagement while...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Tackle customer complaints and drive quality improvements in oligonucleotide products. Collaborate cross-functionally to ensure compliance and enhance customer satisfaction through effective investiga...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$211K - $235K *

Drive patient access initiatives by leveraging oncology expertise to navigate reimbursement landscapes, educate stakeholders, and resolve complex access issues, ensuring timely therapy access for pati...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $190K *

Transform revenue operations by leading AI-driven initiatives, optimizing tech stacks, and enhancing cross-functional collaboration. Drive measurable outcomes while building a high-performing team tha...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$70K - $105K *

Play a key role in delivering comprehensive outpatient behavioral health services to diverse patient populations, focusing on assessment, treatment planning, and collaboration with healthcare teams to...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$200K - $240K *

Shape the future of utilities litigation by providing strategic guidance, managing client relationships, and overseeing complex cases. Leverage your expertise to drive favorable outcomes and mentor ju...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$175K - $210K *

Transform the landscape of emerging therapies by leading strategic clinical innovation, guiding development, and ensuring regulatory readiness for novel therapeutic solutions across early- and mid-sta...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $180K *

Shape the future of regulatory intelligence by leading cross-functional teams, managing global surveillance workstreams, and translating complex regulations into actionable insights for stakeholders a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $195K *

Drive change management initiatives that enhance employee engagement and operational efficiency. Collaborate across teams to ensure successful adoption of technology and policy changes, while providin...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $120K *

Drive initiatives to expand and strengthen laboratory systems for outbreak response and public health, ensuring alignment with national policies and international standards while providing technical l...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$68K - $113K *

Join a team that's dedicated to transforming disability claims through expert clinical assessments. Collaborate with healthcare providers and utilize your clinical expertise to improve patient outcome...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$260K - $300K *

Partner with us to ensure our products meet legal standards while fostering innovation. Collaborate with cross-functional teams throughout the product lifecycle, from design to launch, enabling respon...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $100K *

Join a team that's dedicated to managing regulatory and audit processes, ensuring compliance and operational readiness. As a Senior Analyst, you'll coordinate responses, conduct analysis, and enhance...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $200K *

Transform customer success and support by leading a dynamic team to enhance retention and expansion strategies. Collaborate with executives to build infrastructure and drive growth for 2,100+ accounts...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$110K - $130K *

Tackle new business acquisition by executing strategic sales processes to foster relationships and drive revenue growth in the healthcare IT sector. Collaborate cross-functionally while presenting sol...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $95K *

Unlock potential by leading business analysis to transform processes into actionable requirements for a major financial management system. Collaborate with stakeholders to enhance workflows and ensure...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.