Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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Oncologist Jobs in Iowa

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$72K - $116K *

Unlock potential as a mid-level actuarial analyst, applying statistical techniques to enhance insurance pricing, claims analysis, and profitability studies while progressing through the Actuarial Exec...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Lead a dynamic team in delivering high-quality veterinary care while fostering professional growth and collaboration. Enjoy a supportive environment with modern resources and opportunities for mentors...

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$88K - $105K *

Transform patient care in Emergency Medicine by leading clinical practice, enhancing outcomes, and fostering innovation. Collaborate with a multidisciplinary team to implement evidence-based standards...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Unlock potential by managing and expanding relationships with large enterprise clients. Drive strategic account growth and new business development in the SAP ecosystem, ensuring client satisfaction a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $95K *

Transform integrated communications for vaccine brands by managing client relations, strategic planning, and digital engagement. Leverage traditional and digital strategies to drive impactful outcomes...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$93K - $123K *

Join a team that's dedicated to enhancing patient safety and compliance through effective case management. This role involves coordinating complex healthcare cases, collaborating with stakeholders, an...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$194K - $361K *

Lead the development of innovative NovaOS capabilities, ensuring alignment with business goals and driving continuous improvement through collaboration across cross-functional teams. Deliver measurabl...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$92K - $120K *

Join a dynamic team as a Medical Claims Auditor, ensuring compliance and integrity in healthcare payments. Collaborate with cross-functional teams to identify fraud, waste, and abuse while leveraging...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $154K *

Transform healthcare payment solutions by driving business growth and optimizing client relationships. Leverage your expertise to develop tailored proposals and secure long-term partnerships with larg...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Accelerate client relationships by managing strategic accounts, driving revenue growth, and expanding service lines. Collaborate with internal teams to ensure client satisfaction and deliver tailored...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$172K - $233K *

Join a dynamic team as a Senior Medical Science Liaison, driving scientific engagement with healthcare providers to enhance patient outcomes in obesity and related conditions. Collaborate with key opi...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Contribute to US HR operations by ensuring compliance with employment laws, managing employee data, and supporting onboarding/offboarding processes while collaborating with global HR teams for seamles...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $150K *

Drive growth and strategy for key telehealth categories by leveraging market insights, customer feedback, and cross-functional collaboration to enhance performance and deliver exceptional customer exp...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $190K *

Lead the charge in underwriting and managing complex enterprise accounts, driving profitable business through strategic broker partnerships while mentoring junior underwriters and shaping portfolio st...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Grow enterprise SAP relationships by managing key accounts and driving new business. Leverage your expertise to expand client portfolios, develop strategic plans, and ensure client satisfaction while...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$117K - $161K *

Drive impactful clinical intelligence initiatives by analyzing AI opportunities, conducting feasibility studies, and collaborating with cross-functional teams to enhance patient care and operational e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $350K *

Join a team that's dedicated to providing comprehensive colorectal care. Collaborate with a multispecialty team, support patient access, and enhance program growth in a fully integrated health system...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$140K - $170K *

Join a team that's dedicated to advancing tuberculosis (TB) prevention and care. As a senior technical advisor, you'll lead innovative strategies, collaborate with global partners, and enhance TB prog...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Lead quantitative user research across product lines, shaping strategy and answering critical questions with data-driven insights. Collaborate with teams to prioritize research that mitigates risk and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Transform the insurance appeals process by managing, researching, and drafting compliant responses to billing deductions. Collaborate with legal teams to enhance efficiency and build strong relationsh...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$74K - $99K *

Shape the future of regulatory submissions by ensuring high-quality QC reviews of clinical documents. Collaborate with global teams to meet project timelines while maintaining compliance with industry...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $275K *

Shape the future of mental health care by delivering exceptional outpatient services. Join a dynamic team focused on patient-centered treatment, leveraging modern technology and flexible schedules to...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Elevate clinical operations by managing staff, ensuring compliance, and enhancing patient satisfaction in a dynamic wound healing center. Drive efficiencies and oversee daily functions while fostering...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join us to empower community coalitions in preventing youth substance use. As a Project Officer, you'll manage grants, provide technical assistance, and enhance local capacities, all while collaborati...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Drive sales strategy for Diagnostic Cardiology and Vital Signs Monitors in the Indiana, Ohio, and Kentucky territory. Collaborate with teams to enhance customer support and leverage market insights fo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.