Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.
Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.
High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.
Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.
$88K - $105K *
Elevate care standards by leading our Clinical Department, inspiring your team, and ensuring residents receive exceptional nursing services through effective management and a positive culture...
1 week ago
$90K - $105K *
Lead the Nursing Department to ensure quality care and compliance, overseeing staff, policies, and performance improvement initiatives while fostering a compassionate environment for Guests...
1 week ago
Advanced Practice Provider (FT) |Urgent Care | Ames | PR2026-018
$90K - $110K *
Empower patient care by providing comprehensive services to individuals of all ages. Collaborate with a dedicated team while working independently to enhance community health and well-being in a suppo...
2 weeks ago
Senior Manager, Clinical Conduct
$90K - $110K *
Empower cross-functional teams to drive the Future of Medicine initiatives, ensuring scalable processes and compliance while enhancing patient safety and experience through strategic planning and exec...
2 weeks ago
$205K - $240K *
Shape the future of oncology as a Senior Medical Science Liaison, creating impactful scientific engagement within hematology and oncology that enhances patient care. Collaborate with KOLs and cross-fu...
Reposted 1 week ago
Payer Strategy & Analytics Senior
$103K - $192K *
Shape the future of healthcare reimbursement by leading analytics for payor contracting and out-of-network strategies. Collaborate with cross-functional teams to optimize financial outcomes and drive...
2 days ago
Physician - Community Living Center Medical Director
$180K - $220K *
Lead the Community Living Center, overseeing patient care and safety. Collaborate with an interdisciplinary team to monitor productivity, drive strategic planning, and ensure compliance with quality s...
Reposted 2 days ago
$69K - $119K *
Transform the landscape of clinical documentation by educating and mentoring teams, ensuring compliance, and enhancing documentation accuracy to optimize patient care and coding outcomes...
Yesterday
Director, Managed Markets - Regional - Northeast
$235K - $270K *
Join a team that's driving access strategy across the Northeast, managing key payer relationships and ensuring launch readiness for rare disease therapies. Collaborate with cross-functional teams to o...
3 days ago
$70K - $100K *
Lead the charge in building lasting client relationships while managing accounts, conducting inspections, and delivering tailored pest management solutions. Enjoy uncapped earning potential and compre...
2 days ago
$110K *
Champion the clinical operations team, ensuring project success through resource management, process efficiencies, and compliance. Drive training, metrics development, and mentorship to enhance team c...
Reposted 4 days ago
$135K - $160K *
Help us shape the future of pulmonary care by leveraging your clinical expertise to drive product development, enhance workflows, and ensure effective solutions for COPD, asthma, and other pulmonary c...
2 weeks ago
Medical Review Analyst - Medicare
$66K - $106K *
Lead the charge in conducting medical record reviews and applying clinical judgment to ensure accurate claim payment decisions while supporting fraud investigations and compliance efforts...
3 weeks ago
Sr. Staff Applied AI Engineer (Tech Lead)
$150K - $180K *
Shape the future of AI by leading technical direction and architecture for innovative agent systems. Collaborate with cross-functional teams to ensure quality, security, and efficiency while mentoring...
4 weeks ago
Key Account Manager - Houston, TX
$170K - $205K *
Transform the U.S. sales landscape by driving strategic account plans and fostering relationships in the kidney transplant sector, ensuring optimal product utilization and achieving revenue targets th...
3 weeks ago
Customer Success Manager - New York Metro
$132K - $181K *
Join our team to manage and optimize customer service projects, ensuring timely and quality service delivery. Leverage your expertise to strengthen internal partnerships and drive a positive customer...
Reposted 4 days ago
Nocturnal Hospitalist APP | $5,000 Signing Bonus | 7-on/7-off Schedule
$100K - $120K *
Support our healthcare team by providing critical care and managing patient admissions. Collaborate with diverse medical staff while working autonomously in a dynamic environment. Enjoy a flexible sch...
2 weeks ago
Associate Director, Business Improvement
$130K - $160K *
Reimagine business improvement strategies as a senior contributor, leading high-impact initiatives across functions. Drive alignment, governance, and measurable outcomes while influencing stakeholders...
2 weeks ago
$110K - $130K *
Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...
Yesterday
Sr. Sustainability Engineer - Radiopharmaceutical Manufacturing
$110K - $130K *
Innovate your career with a key role supporting the global launch and technical operations of radiopharmaceuticals, driving compliance, quality initiatives, and collaboration with CDMOs while leading...
Reposted 1 week ago
Clinical Documentation Integrity Supervisor
$110K - $159K *
Inspire excellence in clinical documentation by leading a team of specialists, ensuring quality assurance, and fostering professional development. Collaborate with stakeholders to enhance operational...
Reposted today
Clinical Documentation Integrity Supervisor
$110K - $159K *
Empower the Clinical Documentation Integrity team by ensuring staff competency through quality assurance, training, and performance management. Collaborate on action plans and foster associate develop...
2 days ago
Clinical Documentation Integrity Supervisor
$110K - $159K *
Lead the charge in enhancing clinical documentation integrity by supervising staff, conducting quality reviews, and fostering professional development. Collaborate with teams to implement effective st...
2 weeks ago
$80K - $135K *
Advance educational research by analyzing data and synthesizing findings to enhance student access to advanced courses. Collaborate with stakeholders to design studies, build dashboards, and communica...
1 week ago
Staff Technical Program Manager
$120K - $145K *
Drive execution of complex technical initiatives, translating business vision into actionable programs. Collaborate with cross-functional teams to ensure alignment with company objectives and measurab...
1 week ago
What types of $100,000+ jobs are available in Iowa?
Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.
Which Iowa cities have professional jobs paying $100,000 or more?
Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.
How can I find high-paying jobs in Iowa on Ladders?
Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.
Do Iowa job listings on Ladders include salary information?
Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.