Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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Oncologist Jobs in Iowa

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$210K - $250K *

Lead the charge in providing remote clinical oversight for Dermatology PAs, ensuring high-quality patient care and compliance with regulations. Collaborate with a dedicated team to foster clinical exc...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Transform staff well-being by leading strategic initiatives that enhance resilience and psychosocial support across diverse, high-stress environments, ensuring alignment with organizational priorities...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$130K - $155K *

Lead advanced analytics and statistical modeling to transform complex healthcare data into actionable insights, collaborating with cross-functional teams to solve strategic business challenges and enh...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$77K - $92K *

Join a dynamic team as a Medical Writer, where you'll interpret complex clinical protocols and create essential documentation for clinical studies, ensuring high-quality standards and regulatory compl...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$101K - $136K *

Transform clinical documentation by crafting high-quality regulatory submissions. Collaborate with cross-functional teams to ensure compliance with FDA and ICH guidelines while managing timelines and...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$99K - $136K *

Join a dynamic team as a strategic growth architect, driving revenue and market share expansion in the Hemostasis portfolio. Leverage your expertise in complex healthcare sales to influence decision-m...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$133K - $180K *

Join a team that's redefining member experiences by architecting optimal journeys, bridging operational execution with strategic vision to enhance engagement and satisfaction across all touchpoints...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Healthcare

$115K - $140K *

Empower your career by driving sales in a dynamic environment. As an Account Manager, leverage your expertise to promote our psychiatry portfolio, navigate market complexities, and build strong relati...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$78K - $113K *

Innovate healthcare fraud prevention by leading complex investigations, evaluating medical necessity, and collaborating with regulatory agencies to ensure quality member care and safeguard plan assets...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$78K - $113K *

Unlock potential by leading complex investigations into healthcare fraud, waste, and abuse. Collaborate with regulatory agencies and internal teams to ensure compliance and safeguard member care while...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Lead pioneering evidence generation initiatives to inform oncology product strategies and lifecycle management through cross-functional collaboration and data-driven decision-making...

RemoteRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive customer success by managing key accounts in cattle genomics. Collaborate with cross-functional teams to enhance service delivery, support genomic solutions, and ensure high-quality customer exp...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by providing expert epidemiological insights into occupational exposures for military aviation and firefighter data sets, driving impactful research and analysis to enhance safety...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $105K *

Collaborate with clients and teams to manage projects, expectations, and delivery, ensuring high standards and strategic growth in a fast-paced medical affairs environment. Leverage experience to iden...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $213K *

Transform customer engagement by leading omnichannel marketing strategies, collaborating with cross-functional teams, and leveraging data insights to enhance HCP and patient experiences in the pharmac...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$144K - $205K *

Elevate the quality and impact of AP Social Science courses by leading a diverse team, driving strategic initiatives, and ensuring assessment integrity. Collaborate across departments to enhance stude...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$190K - $300K *

Manage and optimize the digital marketing strategy for oncology products, enhancing customer engagement through innovative digital assets. Lead cross-functional teams to execute comprehensive marketin...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Take ownership of key client relationships, driving growth in the renewable energy analytics sector while collaborating across teams to support long-term strategic goals and ensure client success with...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $95K *

Help us deliver exceptional training and support for medical imaging equipment, enhancing customer experiences through expertise and mentorship while traveling frequently to engage with healthcare pro...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$175K - $219K *

Help us elevate Field Medical operations by optimizing processes, enhancing communication, and driving strategic initiatives to ensure effective engagement and alignment across teams in a dynamic heal...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $170K *

Shape the future of healthcare technology by leveraging your expertise to drive sales success. Collaborate with cross-functional teams to deliver tailored solutions, engage customers, and enhance prod...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Manage and optimize Epic Professional Billing workflows, focusing on Claims and Remittance. Serve as a key resource for end-users, troubleshooting issues and enhancing billing processes to ensure accu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $225K *

Pioneer innovative research strategies to enhance clinical outcomes and drive impactful insights through collaboration across teams, while establishing a robust research infrastructure and publication...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$132K - $178K *

Champion quality in In-Vitro Diagnostics and Companion Diagnostics. Lead proactive strategies, ensuring compliance in clinical trials while collaborating with partners to enhance precision medicine in...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K *

Engage with healthcare professionals to drive growth in advanced wound care. Collaborate with cross-functional teams to develop strategies, expand accounts, and build strong relationships, ensuring ef...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.