Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Oncologist Jobs in Iowa

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$110K - $140K *

Drive your sales career forward by leading strategic discovery conversations and developing enterprise accounts. Collaborate with technical teams to engage prospects, understand their security needs...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $115K *

Transform clinical trial operations by leading a high-performing team, ensuring efficient RFP reviews and testing requirements. Collaborate cross-functionally to drive business objectives and enhance...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Empower our team by overseeing clinical trial activities, managing resources, and ensuring compliance with established procedures. Collaborate with cross-functional teams to drive operational excellen...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$155K - $185K *

Partner with us to lead high-impact projects in healthcare marketing, managing budgets and teams while ensuring creative excellence and strategic alignment. Drive client success through collaboration...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Join a dynamic team to optimize supply chain operations, ensuring efficient medication delivery from pharmacy partners to patients. Oversee systems, processes, and a team to scale operations amidst ra...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$76K - $114K *

Shape the future of healthcare by driving growth in Electrophysiology-focused Ambulatory Surgery Centers. Leverage your clinical expertise to build relationships, enhance product adoption, and ensure...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$223K - $313K *

Collaborate with a dedicated team of physicians to ensure high-quality inpatient care through clinical expertise, thorough reviews, and utilization management. Advance patient outcomes by utilizing st...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $195K *

Innovate member experience strategies by translating enterprise goals into actionable plans. Drive performance improvements in CAHPS and HOS programs through provider engagement and data analysis, ens...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $110K *

Unlock better healthcare experiences by providing telephonic triage and support. As a key advocate for members, you'll connect them with essential resources, ensuring timely and appropriate care while...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's redefining telehealth by delivering exceptional psychotherapy to older adults. Enjoy flexible hours, comprehensive support, and opportunities for professional growth while making a...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $130K *

Shape the future of mental health care by providing virtual counseling and developing treatment plans for patients with acute conditions. Collaborate with medical professionals while ensuring adherenc...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Technical Services

$100K - $115K *

Elevate your career by driving growth and operations in health plan partnerships. This role combines sales enablement and partner operations, directly impacting revenue through strategic collaboration...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$205K - $380K *

Accelerate progress at enterprise sales by driving strategic growth initiatives, building relationships with healthcare leaders, and leading complex sales pursuits to enhance market presence and custo...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$246K - $332K *

Drive pediatric development strategy by integrating clinical insights and regulatory commitments across multiple therapeutic areas, ensuring effective execution from candidate transition to post-marke...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Drive the success of clinical trials by overseeing compliance with regulations and protocols. Engage in site management, monitor data integrity, and ensure patient safety while collaborating with site...

Iowa, USRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$186K - $278K *

Lead strategic initiatives in healthcare economics, collaborating with national accounts to enhance patient outcomes and drive market access. Foster relationships with key stakeholders while executing...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Join a team that's redefining billing solutions in the legal sector. Leverage your expertise in law firm financial operations to support sales efforts, conduct client demos, and enhance our innovative...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$150K - $200K *

Lead client engagements by leveraging tax expertise to drive revenue growth, manage complex planning discussions, and enhance client relationships while ensuring strategic alignment across teams for o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Join us to lead payer contracting strategies, negotiate complex agreements, and enhance reimbursement performance across diverse healthcare models while managing a high-performing team in a dynamic, r...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$235K - $270K *

Unlock your potential as a strategic leader in field medical operations, driving scientific exchange and enhancing patient identification. Collaborate with key opinion leaders while building scalable...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Champion a transformative product vision, leading cross-functional teams to drive strategic outcomes in a dynamic digital health environment. Shape the future of patient care and client experience whi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Unlock the potential of crypto intelligence by owning in-depth analyses of DPRK and Chinese financial threats, tracing illicit networks, and producing actionable insights for stakeholders across the g...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $322K *

Join a team that's dedicated to delivering compassionate psychiatric care to incarcerated individuals with complex needs. Collaborate with a multidisciplinary team to support recovery and improve ment...

1 month ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$210K - $250K *

Lead the charge in providing remote clinical oversight for Dermatology PAs, ensuring high-quality patient care and compliance with regulations. Collaborate with a dedicated team to foster clinical exc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Transform staff well-being by leading strategic initiatives that enhance resilience and psychosocial support across diverse, high-stress environments, ensuring alignment with organizational priorities...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.