Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Oracle Application Systems Analyst (Mid-Level)
$83K - $112K *
Transform your career by leveraging your analytical skills to enhance application systems. Collaborate with teams to improve workflows, execute tests, and support mission-driven initiatives that stren...
1 week ago
Account Executive, Enterprise Suite - Corporate
$124K - $171K *
Champion the future of enterprise sales by driving top-down solutions into global enterprises. Leverage AI and LLM technologies to enhance client insights and foster relationships across all organizat...
3 days ago
Program Chief Engineer, Cyclops (Remote considered)
$190K - $275K *
Elevate technical excellence as the Chief Engineer, guiding multidisciplinary teams to ensure mission success through robust architecture, requirements management, and strategic decision-making in com...
3 weeks ago
Program Chief Engineer, Cyclops (Remote considered)
$190K - $275K *
Drive the technical vision for a major interceptor product, ensuring mission success through robust architecture, requirements management, and cross-disciplinary collaboration. Lead teams to maintain...
3 weeks ago
Solutions Architect, Digital Platforms
$188K - $282K *
Drive the architecture for customer data integration across digital platforms, ensuring secure ingestion and transformation. Collaborate with cross-functional teams to create scalable solutions that e...
Yesterday
Senior/Staff AI Scientist, Antibody Design
$150K - $180K *
Transform innovative protein design through advanced AI techniques, enhancing antibody drug discovery. Collaborate across disciplines to maximize efficiency and impact, while leading research that set...
Reposted 4 weeks ago
Senior Legal Analyst & Litigation Project Manager
$92K - $124K *
Partner with us to enhance legal operations and implement eDiscovery processes. You'll lead customer data privacy initiatives, improving cross-functional collaboration and response strategies for comp...
Reposted 4 weeks ago
Solutions Architect, Enterprise
$224K - $326K *
Serve as a technical leader for large customers, guiding AI cloud strategies. Connect business priorities with scalable architecture while managing executive engagements and navigating complex decisio...
Reposted 1 week ago
Care Manager, Telephonic Nurse
$71K - $97K *
Transform patient care by guiding transitions and ensuring optimal service continuity. Leverage your nursing expertise to navigate healthcare options and advocate for patients in need of post-acute se...
Yesterday
Senior Director, Biostatistics
$295K - $314K *
Drive strategic biostatistical leadership for clinical development programs, overseeing statistical activities, collaborating with cross-functional teams, and ensuring high-quality data analysis to su...
3 weeks ago
Account Specialist (Altoona, PA)
$160K - $192K *
Transform commercial performance by engaging healthcare providers, driving product adoption, and collaborating with cross-functional teams to ensure patient access to innovative therapies across a def...
1 week ago
Regional Medical Science Director (South)
$200K - $235K *
Unlock potential by driving scientific excellence as a strategic partner, educating healthcare professionals on Immuno-Oncology and fostering relationships that support cancer therapeutic initiatives...
Reposted 1 week ago
Senior Director, Product Management, Agentic Platform
$192K - $303K *
Empower innovation as you lead the strategy and development of core platform primitives, driving the future of agentic systems and ensuring product teams can rapidly create and deploy advanced agents...
3 weeks ago
Lead Consultant CDH Implementation
$105K - $149K *
Transform complex Consumer-Directed Health implementations for major employers. Lead strategy, execution, and client engagement while serving as a subject-matter expert to ensure operational excellenc...
3 days ago
$110K - $130K *
Unlock potential by driving client success for enterprise accounts. Lead customer engagement, ensure adoption of solutions, and collaborate effectively with teams to promote renewals, expansion, and s...
Reposted 3 weeks ago
$145K - $191K *
Lead the charge in designing scalable cloud solutions that meet diverse healthcare needs, ensuring alignment with enterprise architecture and driving technology initiatives across multiple platforms t...
Reposted 1 month ago
$110K - $130K *
Advance client relationships and team performance as a strategic leader, overseeing captive insurance operations, driving excellence, and enhancing service delivery while managing complex engagements...
1 week ago
Senior Relationship Manager, Agribusiness
$128K - $268K *
Shape client relationships and business strategies in agribusiness. Engage with stakeholders to drive growth, manage credit quality, and deliver tailored financial solutions, ensuring performance targ...
Reposted 4 weeks ago
Senior Product and Design Strategist
$192K - $240K *
Unlock your potential as a Product + Design Strategist, leading ambiguous projects from concept to execution. Collaborate with cross-functional teams to create innovative, user-centered experiences an...
Reposted 4 weeks ago
Director, Telehealth Sales & Strategic Partnerships
$130K - $160K *
Accelerate growth in telehealth by leading strategic partnerships and business development. Drive revenue through innovative solutions, executive relationships, and a deep understanding of the healthc...
2 weeks ago
Director, Telehealth Sales & Strategic Partnerships
$135K - $160K *
Join a dynamic team to drive telehealth sales and strategic partnerships, identifying opportunities and building relationships across the healthcare ecosystem. Own the commercial process from prospect...
2 weeks ago
Senior Staff Forward Deployed Engineer
$152K - $205K *
Lead the charge in architecting AI-driven solutions for enterprise clients, transforming complex data governance challenges into actionable insights. Collaborate with stakeholders to shape product evo...
3 weeks ago
Senior Director, Counsel - Litigation, Legal Policy and Strategy (USA Remote role)
$199K - $321K *
Explore a dynamic role shaping litigation and policy strategy in the pharmaceutical sector. Collaborate with senior leaders and external stakeholders to navigate complex legal landscapes, ensuring pat...
Yesterday
Study Manager - Infectious Disease
$95K - $115K *
Lead the charge in managing interdisciplinary clinical research studies, ensuring compliance with GCP and regulatory requirements while driving project delivery, quality, and financial performance. Bu...
2 weeks ago
$250K - $500K *
Lead the charge in transforming wound care practices, utilizing advanced techniques to enhance patient outcomes in diverse healthcare settings, while collaborating with multidisciplinary teams to ensu...
3 days ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.