Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Account Manager, Life Sciences
$100K - $120K *
Transform client relationships by driving retention and growth in a dynamic SaaS environment. Collaborate with diverse stakeholders to maximize product adoption and uncover new opportunities, ensuring...
3 weeks ago
$120K - $147K *
Shape your career by leading data integration initiatives that drive enterprise-wide consistency and governance. Collaborate with stakeholders to deliver trusted, scalable data products while ensuring...
1 week ago
Director or Senior Director of Translational Medicine
$235K - $310K *
Join a team that empowers translational medicine innovation in early-phase oncology, owning strategies from IND-enabling studies to proof of concept. Drive impactful biomarker integration and clinical...
Reposted today
Senior Director, Regulatory Affairs
$211K - $281K *
Champion regulatory excellence by leading U.S. FDA engagement and strategy for product development, ensuring timely approvals and compliance while driving cross-functional collaboration and organizati...
3 weeks ago
Clinical Liaison and Market Dev. Leader
$110K - $130K *
Join a team that's driving innovation in transplant advocacy by integrating business development, marketing, and medical expertise. Collaborate with key stakeholders to enhance KOL engagement and mark...
3 weeks ago
Physician - Diagnostic Tele-Radiologist
$210K - $250K *
Grow your career by providing comprehensive diagnostic radiology services, including consultations and interpretations for a diverse patient population. Collaborate remotely to ensure timely and accur...
1 week ago
BAPTIST MEDICAL CENTER EAST - HM - MEDICAL DIRECTOR
$250K - $300K *
Reimagine healthcare leadership by guiding our hospital medicine program. Drive excellence, mentor clinicians, and enhance patient care while collaborating with administration to improve operational p...
2 weeks ago
Identity Operations Service Lead
$162K - $292K *
Join a team that's redefining identity operations by leading a 24/7 team to enhance access management strategies. You'll shape the vision, drive process innovation, and foster talent in a collaborativ...
Reposted 6 days ago
Assoc Dir, Neuro Thought Leader Liaison (South region)
$190K - $225K *
Shape the future of healthcare by driving strategic KOL engagement and insight generation in rare neurology. Collaborate with thought leaders to influence brand strategy and enhance patient outcomes t...
1 month ago
$80K - $95K *
Join a dynamic team to enhance decision-making and support EHRM initiatives. Drive program management, facilitate stakeholder engagement, and contribute to strategic communications while ensuring effe...
4 weeks ago
Principal, Strategic Partnerships, Health Systems
$150K - $180K *
Unlock potential by driving partnerships within health systems, building strategic relationships, and creating impactful ecosystems that accelerate product adoption and streamline sales cycles, while...
Reposted 1 week ago
$120K - $160K *
Contribute to the evolution of data-driven healthcare products, shaping strategy and execution. Collaborate with cross-functional teams to deliver AI-enabled solutions that enhance clinical outcomes a...
2 weeks ago
Bone Access & DMAB Patient Experience Lead, Marketing Senior Manager
$149K - $202K *
Make your mark at the forefront of patient access marketing, leading strategies and initiatives to enhance the Bone portfolio experience. Collaborate cross-functionally to optimize access solutions an...
1 week ago
Director, Medical Science Liaison (East)
$148K - $222K *
Drive clinical adoption and enhance partnerships by leading a high-performing Medical Science Liaison team. Collaborate with sales and medical teams to educate stakeholders, influence decision-making...
1 week ago
Director, Sales – Global Strategic Accounts
$150K - $180K *
Empower a high-performing sales team to drive strategic growth and customer engagement in the biopharma sector. Lead complex sales initiatives, build executive relationships, and translate business st...
Yesterday
$250K - $300K *
Join a dynamic multi-specialty practice as a Comprehensive Ophthalmologist, where you'll manage a significant surgical volume, collaborate with a skilled team, and benefit from corporate support to en...
4 weeks ago
Cardiovascular Account Specialist - U.S. Sales, Philadelphia East, PA
$162K - $195K *
Shape the future of cardiovascular care by driving the launch of a novel cardiac myosin inhibitor. Collaborate with healthcare professionals and internal teams to establish strategic relationships and...
Yesterday
$84K - $99K *
Join a dynamic team to evaluate and process medication prior authorization requests, ensuring compliance with clinical guidelines and regulatory standards while facilitating timely patient access to n...
1 week ago
Contrast Media Clinical Sales Specialist
$97K - $146K *
Partner with us to provide clinical support for contrast media, delivering education and product expertise to healthcare professionals while collaborating with internal teams to enhance patient care a...
2 weeks ago
Ambulatory Client Sales Executive
$100K - $120K *
Serve as the primary contact for clients, driving engagement and service quality while fostering relationships with key stakeholders and leveraging expertise to enhance organizational growth and clien...
Reposted 2 weeks ago
Manager, Regulatory Affairs (Clinical Labeling)
$110K - $130K *
Take ownership of IMP labeling processes, ensuring compliance with global regulations and quality standards while collaborating cross-functionally to support clinical trial timelines and enhance label...
4 weeks ago
Senior Director, Corporate Counsel
$175K - $210K *
Lead corporate legal strategy and M&A transactions, guiding complex deals and governance. Manage a growing legal team, develop processes, and partner with senior leadership to drive business initiativ...
1 week ago
Director - AI Digital Product Management - Commercial Value & Access
$199K - $269K *
Grow your career with a leadership role in AI Digital Product Management, driving strategy and innovation across a portfolio of AI products. Collaborate with cross-functional teams to deliver scalable...
3 weeks ago
Senior Consultant, Advisory Services
$90K - $150K *
Elevate healthcare performance by leading analytics-driven consulting engagements. Collaborate with clients to identify needs, deliver insights, and implement solutions while managing project economic...
4 weeks ago
$140K - $170K *
Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...
3 weeks ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.