Find $100K+ Professional Jobs in Ohio

Explore high-paying professional opportunities across Ohio with Ladders. Browse vetted roles with salaries of $100,000 or more in major employment centers such as Columbus, Cleveland, Cincinnati, Dayton, and Akron. Whether you’re seeking your next leadership position or a specialized role, discover openings across a range of industries and experience levels.

Explore Ohio’s Major Job Markets

Ohio’s diverse economy creates opportunities in metropolitan hubs and communities throughout the state. Search roles in Columbus, a center for business, healthcare, government, and technology; Cleveland, with opportunities in healthcare, manufacturing, finance, and professional services; and Cincinnati, known for corporate headquarters, consumer goods, logistics, and healthcare. You can also explore positions in Dayton, Akron, Toledo, and other Ohio locations.

Industries and Career Paths

Ohio employers hire experienced professionals across industries including healthcare, technology, engineering, manufacturing, finance, sales, operations, and executive leadership. Available positions and compensation vary by employer, role, location, and qualifications. Use search filters to focus on the fields and opportunities that match your career goals.

Find the Right Ohio Opportunity

Review job requirements, responsibilities, location, and compensation details to identify roles that fit your experience. Keep your profile and résumé current, set up job alerts, and check back often to find newly posted opportunities. Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore their next career move in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $125,316

Sort By: Relevance

$105K - $150K *

Inspire impactful change by leading complex federal digital services programs. Oversee strategy, execution, and customer relationships while managing multidisciplinary teams to deliver high-quality te...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the product vision and strategy for a cutting-edge cloud service, shaping capabilities and defining AI-driven insights while collaborating with engineering and operations teams to ensure market a...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Join a team that's shaping evidence strategies and insights in health economics and outcomes research. Lead client engagements, oversee analytics, and drive impactful decision-making in biopharma and...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's shaping the future of our Salesforce platform. Lead development, enhance integrations, and optimize data management while collaborating with cross-functional teams to drive business...

4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Join a team that's shaping the future of software development by leading projects, mentoring engineers, and architecting innovative solutions that enhance performance and meet business goals in a coll...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $205K *

Unlock the potential of our Pro offering by leading product strategy and roadmap. Collaborate across teams to enhance customer experiences for short-term rental operators and HOAs, ensuring scalable s...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$138K - $214K *

Optimize project outcomes by leading preconstruction efforts for large-scale Data Center initiatives. Drive team performance, manage budgets, and ensure exceptional client relationships while overseei...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$92K - $120K *

Join a dynamic team as a Medical Claims Auditor, ensuring compliance and integrity in healthcare payments. Collaborate with cross-functional teams to identify fraud, waste, and abuse while leveraging...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$197K - $255K *

Lead the charge in AI transformation by optimizing data center design and accelerating value realization. Serve as a subject-matter expert, guiding strategic implementations and mentoring teams to dri...

RemoteRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Champion client success by managing key relationships and driving strategic initiatives. Lead cross-functional teams to deliver high-quality work while ensuring financial performance and growth for as...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Advance your career by building high-throughput services that power AI workflows. Collaborate with cross-functional teams to design scalable infrastructure and tackle complex challenges in a dynamic e...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $110K *

Join a dedicated team providing quality patient care while enhancing access and satisfaction. Collaborate with healthcare professionals, lead initiatives, and support continuous learning to foster a p...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$175K - $210K *

Lead pioneering evidence generation initiatives to inform oncology product strategies and lifecycle management through cross-functional collaboration and data-driven decision-making...

RemoteRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$177K - $265K *

Join a team that's dedicated to safeguarding player experiences by investigating and combating cheating in games. Leverage your analytical skills to create data-driven reports and collaborate with eng...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$150K - $180K *

Lead and grow a high-performing platform engineering team, setting vision and roadmap while collaborating with cross-functional leaders to enhance product velocity and reliability for enterprise custo...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in client strategy and Meta campaign management, ensuring optimal performance and strong relationships. Own a portfolio of accounts, drive results, and proactively solve issues to enha...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$146K - $206K *

Join a dynamic team to build secure customer authentication features, enhancing user experiences across B2C and B2B platforms. Collaborate with engineers to develop backend services and APIs, ensuring...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Take ownership of client relationships and campaign performance, managing a portfolio of accounts. Lead strategy discussions, optimize Meta campaigns, and ensure client satisfaction through proactive...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Empower a high-performing national accounts team by developing strategies that drive growth, retention, and new business. Collaborate across functions to enhance customer relationships and deliver mea...

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Innovate AI solutions by developing tools and integrations that enhance workflows, drive efficiency, and empower teams. Collaborate across departments to implement scalable AI applications that delive...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$94K - $143K *

Lead the charge in developing structural designs using advanced modeling software. Collaborate with multi-disciplinary teams to create detailed drawings and resolve design challenges, ensuring timely...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Technical Services

$162K - $200K *

Unlock your potential by serving as a key legal partner, guiding commercial transactions and enhancing our legal infrastructure while collaborating cross-functionally to drive efficiency and complianc...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$190K - $285K *

Shape the future of database protection by owning the Oracle roadmap, collaborating with engineering teams, and driving cross-database initiatives to enhance recovery solutions for critical enterprise...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Transform enterprise sales strategies by identifying and addressing client needs in Logistics and Manufacturing. Drive national account growth through innovative solutions, relationship building, and...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Staffing

$87K - $108K *

Join a team that's shaping the future of water and energy utilities by leading proposal development, coordinating resources, and implementing winning strategies. Collaborate with experts to create imp...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, management, executive, and specialized positions in fields such as healthcare, technology, engineering, manufacturing, finance, sales, and operations. Roles and salaries vary by employer and qualifications.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, Dayton, Akron, Toledo, and other Ohio communities. Availability changes as employers post and fill positions.

  • Are the Ohio jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Review each listing for its specific compensation and requirements.

  • How can I find a suitable job in Ohio?question toggle

    Search by location, job title, industry, or other relevant filters. Compare the qualifications, responsibilities, location, and compensation listed for each role, and keep your résumé and profile up to date.