Find $100K+ Professional Jobs in Ohio

Explore high-paying professional opportunities across Ohio with Ladders. Browse vetted roles with salaries of $100,000 or more in major employment centers such as Columbus, Cleveland, Cincinnati, Dayton, and Akron. Whether you’re seeking your next leadership position or a specialized role, discover openings across a range of industries and experience levels.

Explore Ohio’s Major Job Markets

Ohio’s diverse economy creates opportunities in metropolitan hubs and communities throughout the state. Search roles in Columbus, a center for business, healthcare, government, and technology; Cleveland, with opportunities in healthcare, manufacturing, finance, and professional services; and Cincinnati, known for corporate headquarters, consumer goods, logistics, and healthcare. You can also explore positions in Dayton, Akron, Toledo, and other Ohio locations.

Industries and Career Paths

Ohio employers hire experienced professionals across industries including healthcare, technology, engineering, manufacturing, finance, sales, operations, and executive leadership. Available positions and compensation vary by employer, role, location, and qualifications. Use search filters to focus on the fields and opportunities that match your career goals.

Find the Right Ohio Opportunity

Review job requirements, responsibilities, location, and compensation details to identify roles that fit your experience. Keep your profile and résumé current, set up job alerts, and check back often to find newly posted opportunities. Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore their next career move in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $125,313

Sort By: Relevance

$110K - $125K *

Pioneer the implementation of Interactive Response Technology (IRT) in clinical studies. Lead cross-functional teams, manage timelines, and ensure compliance while providing expert guidance and suppor...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $142K *

Unlock potential by leading clinical trial monitoring efforts, ensuring compliance and data integrity while collaborating with study teams. Your expertise will enhance patient safety and contribute to...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that's shaping the future of real-time payments data by designing core platform capabilities, optimizing performance, and driving operational excellence across the enterprise...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$99K - $164K *

Elevate client relationships by managing strategic partnerships, ensuring satisfaction, and identifying growth opportunities. Collaborate with teams to enhance service delivery and drive business succ...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Contribute to compliance excellence by reviewing processes, ensuring adherence to regulations, and providing consultative guidance. Collaborate with stakeholders to implement solutions that align with...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$157K - $265K *

Unlock your potential as a Senior Product Manager, driving AI and automation innovations. Collaborate with cross-functional teams to shape customer experiences and deliver impactful solutions in a dyn...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$87K - $114K *

Shape the future of quality assurance in fintech by collaborating with agile teams to enhance software testing and automation, ensuring robust and secure payment solutions that impact users globally...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Shape the architecture of a strategic enterprise platform, driving innovation and performance while mentoring engineers and establishing technical standards to enhance scalability and reliability acro...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$205K - $341K *

Unlock your potential by leading regulatory strategies for advertising and promotion. Collaborate with cross-functional teams to ensure compliance and drive successful commercialization initiatives in...

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3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Engage in shaping a robust Environmental, Health, Safety, and Sustainability culture across 2,200+ retail locations. Collaborate with leadership to ensure compliance and drive operational excellence t...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$61K - $104K *

Manage store operations and drive sales while ensuring exceptional customer service. Lead a team to meet business goals, maintain inventory, and foster customer loyalty in a dynamic retail environment...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Engage with national accounts to drive sales and enhance customer satisfaction. Leverage local relationships and coordinate with internal teams to implement strategic growth plans in the fleet busines...

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Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Join a team that's redefining enterprise data architecture by developing standards and governance for data management, optimizing information flow, and enhancing accessibility while ensuring security...

3 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$188K - $230K *

Join a team that's driving innovation in data center materials. You'll manage strategic accounts, lead complex negotiations, and collaborate with global teams to enhance customer relationships and dri...

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3 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $120K *

Develop your career by providing technical support and consulting to ensure successful customer integration of complex bolting solutions. Collaborate with teams to meet customer needs through effectiv...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $143K *

Elevate your career by leading outpatient dialysis care, overseeing treatment, guiding clinical staff, and ensuring the highest standards of patient safety and compassion in a dynamic, team-oriented e...

3 days ago

  •   15+ years exp.  •   Healthcare

$93K - $210K *

Join a team that's dedicated to enhancing compensation strategies and driving business performance. Lead a talented group of professionals while collaborating with stakeholders to optimize compensatio...

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3 days ago

  •   5 - 7 years exp.  •   Transportation

$122K - $184K *

Lead impactful implementations of Workday solutions, driving customer success through effective configuration, testing, and expert guidance in HCM Reporting & Analytics. Engage with diverse teams to m...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$95K - $115K *

Design and develop advanced mechanical systems for ultra-low temperature refrigeration. Collaborate with cross-functional teams to innovate, optimize performance, and ensure regulatory compliance whil...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Lead the charge in ensuring quality excellence by maintaining compliance and driving improvements in quality systems. Collaborate with cross-functional teams to investigate issues, implement correctiv...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $162K *

Innovate in a strategic sales role, managing key accounts and driving revenue growth. Leverage technical expertise to build relationships and influence decision-making across the F5 solution portfolio...

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3 days ago

  •   8 - 10 years exp.  •   Information Technology

$169K - $254K *

Lead and optimize the Solutions Engineering team in the Healthcare sector, focusing on technical sales and strategic planning. Drive team performance, manage recruitment, and ensure alignment with com...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$72K - $192K *

Join a team that's dedicated to enhancing client relationships in healthcare. As a trusted advisor, you'll guide clients through workflows, drive feature adoption, and develop strategic plans to maxim...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $134K *

Join a team that's redefining financial planning by creating comprehensive tax strategies. Collaborate with advisors to analyze client data, deliver tailored tax plans, and stay updated on tax laws to...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$129K - $170K *

Champion compliance and legal support across privacy, SaaS contracts, and IP. Collaborate with teams on AI/ML, marketing, and product development while ensuring adherence to regulations and fostering...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, management, executive, and specialized positions in fields such as healthcare, technology, engineering, manufacturing, finance, sales, and operations. Roles and salaries vary by employer and qualifications.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, Dayton, Akron, Toledo, and other Ohio communities. Availability changes as employers post and fill positions.

  • Are the Ohio jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Review each listing for its specific compensation and requirements.

  • How can I find a suitable job in Ohio?question toggle

    Search by location, job title, industry, or other relevant filters. Compare the qualifications, responsibilities, location, and compensation listed for each role, and keep your résumé and profile up to date.