Find $100K+ Professional Jobs in Ohio

Explore high-paying professional opportunities across Ohio with Ladders. Browse vetted roles with salaries of $100,000 or more in major employment centers such as Columbus, Cleveland, Cincinnati, Dayton, and Akron. Whether you’re seeking your next leadership position or a specialized role, discover openings across a range of industries and experience levels.

Explore Ohio’s Major Job Markets

Ohio’s diverse economy creates opportunities in metropolitan hubs and communities throughout the state. Search roles in Columbus, a center for business, healthcare, government, and technology; Cleveland, with opportunities in healthcare, manufacturing, finance, and professional services; and Cincinnati, known for corporate headquarters, consumer goods, logistics, and healthcare. You can also explore positions in Dayton, Akron, Toledo, and other Ohio locations.

Industries and Career Paths

Ohio employers hire experienced professionals across industries including healthcare, technology, engineering, manufacturing, finance, sales, operations, and executive leadership. Available positions and compensation vary by employer, role, location, and qualifications. Use search filters to focus on the fields and opportunities that match your career goals.

Find the Right Ohio Opportunity

Review job requirements, responsibilities, location, and compensation details to identify roles that fit your experience. Keep your profile and résumé current, set up job alerts, and check back often to find newly posted opportunities. Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore their next career move in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,781

Sort By: Relevance

$88K - $154K *

Join a dynamic team as a Document Control Supervisor, overseeing document management for construction and engineering projects. Drive process improvements, ensure compliance, and support project teams...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$59K - $156K *

Optimize healthcare IT solutions by collaborating with teams to enhance Epic Cadence Prelude workflows, ensuring seamless integration and performance metrics while supporting client needs and project...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$88K - $105K *

Drive system administration excellence by managing Windows servers, ensuring compliance, and automating processes. Collaborate with teams to enhance infrastructure and support key technology initiativ...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Drive performance and growth in Production Operations by leading a high-performing team focused on safety, quality, and continuous improvement. Balance daily operations with long-term strategic planni...

Reposted yesterday

  •   5 - 7 years exp.  •   Media

$142K - $188K *

Empower your career by leading Treasury's analytics framework, optimizing workflows, and enhancing data governance. Collaborate with stakeholders to drive digital transformation and support data-drive...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Empower patient care by providing expert Hematology/Oncology services, managing outpatient treatments, and engaging in clinical documentation and departmental reporting to enhance healthcare delivery...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$130K - $160K *

Join a team that's shaping the future of DevSecOps by guiding customers in building robust processes. Collaborate across departments to deliver tailored solutions and showcase the value of innovative...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$260K - $330K *

Transform enterprise security strategy and governance in a high-growth healthcare AI environment. Collaborate with leadership to embed security across products and operations, ensuring compliance and...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$97K - $180K *

Lead data-driven initiatives to solve complex business challenges, leveraging analytical skills to provide insights and recommendations. Collaborate with teams to enhance competitive intelligence and...

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Transform healthcare auditing by ensuring clinical documentation accuracy and compliance. Leverage your expertise in ICD-10 coding and DRG claims to enhance quality standards and drive process improve...

Yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Unlock potential by driving new business sales in a dynamic, AI-enabled environment. Own your territory, create a robust pipeline, and engage sophisticated buyers to deliver consistent revenue growth...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Shape the future of financial partnerships by driving revenue through strategic alliances with banks and fintechs. Collaborate cross-functionally to enhance Socure's market presence and ensure seamles...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$150K - $184K *

Lead the charge in enhancing platform security and infrastructure as a Senior Software Engineer. Utilize your Python expertise and SRE mindset to drive critical improvements, mentor teammates, and ens...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $175K *

Lead the charge in advancing oncology diagnostics by managing a team of bioinformaticians and data scientists, driving product development, and ensuring high-quality analysis and validation of ctDNA-b...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K *

Lead and develop a high-performing SDR team to enhance sales pipeline efficiency, ensuring timely responses and quality prospect engagement through data-driven strategies and collaborative processes w...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Empower product innovation by driving engineering excellence in new product development, process improvement, and manufacturing efficiency. Collaborate with cross-functional teams to ensure quality an...

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $120K *

Lead the charge in managing electrical installations for utility-scale solar projects. Oversee contractor coordination, ensure quality control, and foster strong relationships while navigating a dynam...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $145K *

Lead quantitative user research across product lines, shaping strategy and answering critical questions with data-driven insights. Collaborate with teams to prioritize research that mitigates risk and...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Transform cybersecurity by leading the enterprise adversary emulation program. Oversee complex attack simulations, validate security controls, and drive improvements across teams to enhance detection...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$119K - $149K *

Lead full-cycle recruiting for technical and analytical roles, partnering with teams to define success and build diverse talent pipelines. Utilize creative sourcing and data-driven insights to enhance...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $130K *

Lead comprehensive Medical Loss Ratio examinations, ensuring compliance with ACA regulations. Oversee examiners, manage communications, and analyze data to deliver accurate results. Work remotely in a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $100K *

Champion the creative process by managing digital ad production, enhancing workflows, and collaborating with cross-functional teams to deliver high-quality marketing assets on time. Drive innovation a...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Optimize enterprise monitoring solutions by administering Dynatrace, enhancing application performance, and ensuring operational observability across diverse environments. Collaborate with teams to im...

Columbus, OHRemote

2 days ago

  •   5 - 7 years exp.  •   Staffing

$144K - $192K *

Drive quality assurance in software development by automating tests and enhancing analytics. Collaborate with cross-functional teams to tackle complex challenges across platforms, ensuring robust prod...

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Drive enterprise observability by implementing and optimizing Dynatrace monitoring solutions. Collaborate across teams to enhance application performance, infrastructure monitoring, and incident respo...

2 days ago

  •   5 - 7 years exp.  •   Staffing

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, management, executive, and specialized positions in fields such as healthcare, technology, engineering, manufacturing, finance, sales, and operations. Roles and salaries vary by employer and qualifications.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, Dayton, Akron, Toledo, and other Ohio communities. Availability changes as employers post and fill positions.

  • Are the Ohio jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Review each listing for its specific compensation and requirements.

  • How can I find a suitable job in Ohio?question toggle

    Search by location, job title, industry, or other relevant filters. Compare the qualifications, responsibilities, location, and compensation listed for each role, and keep your résumé and profile up to date.