Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$235K - $310K *

Join a team that empowers translational medicine innovation in early-phase oncology, owning strategies from IND-enabling studies to proof of concept. Drive impactful biomarker integration and clinical...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Champion supply chain strategy and execution for clinical operations, ensuring timely, compliant delivery of materials for global oncology trials. Collaborate with cross-functional teams to manage ris...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $195K *

Join a dynamic biotech team to drive strategic initiatives, manage cross-functional operations, and lead business development efforts. Leverage your scientific expertise and leadership skills to shape...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$165K - $200K *

Deliver exceptional user experiences by refining complex tools into intuitive designs. Collaborate closely with engineers to enhance UX, ensuring our LLM platform meets user needs with responsiveness...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive customer support excellence by managing a frontline team to ensure timely resolutions, operational efficiency, and a culture of continuous improvement, paving the way for stellar service in heal...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$114K - $191K *

Lead the charge in shaping high-impact SaaS solutions by driving technical strategy and empowering a high-performing engineering team. Collaborate across disciplines to foster innovation in a fast-pac...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $175K *

Lead community engagement initiatives to enhance patient advocacy for Becker Muscular Dystrophy. Collaborate with local organizations, educate patients, and build networks to ensure access to quality...

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Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a dynamic team to deliver innovative design engineering solutions for power projects. Leverage your expertise in mechanical engineering to create impactful designs and ensure project success thro...

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Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $125K *

Advance business growth by fostering relationships and crafting innovative strategies that drive revenue. Collaborate across teams to identify opportunities and enhance operational excellence while en...

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Reposted today

  •   Less than 5 years exp.  •   Business Services

$105K - $255K *

The Senior Account Executive at Justworks is responsible for expanding the user base and driving significant growth by managing a complete end-to-end sales pipeline. This role requires a proven closer...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Business Services

$83K - $163K *

Accelerate your career by managing a full sales cycle, from prospecting to closing deals. Engage with the entrepreneurial community and drive revenue growth while building lasting relationships in you...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Business Services

$85K - $103K *

As an Account Executive in-territory in Miami, you will be responsible for managing the full sales cycle, including building and managing a sales pipeline, prospecting, and closing deals. This role re...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Business Services

$72K - $97K *

Transform automation systems by troubleshooting and enhancing PLC and PC controls. Collaborate with maintenance teams to ensure reliability and accuracy in production processes while overseeing upgrad...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Partner with us to enhance relationships with executive partners, enabling pipeline growth and revenue generation. Leverage cross-functional collaboration while managing multiple engagements, driving...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Transform client engagement by driving growth in untapped markets, shaping impactful solutions, and delivering measurable results. Collaborate with diverse teams to connect client needs with innovativ...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$107K - $195K *

Join a team that's shaping the future of microgrid automation and renewable energy. Leverage your expertise in control systems and collaborate on innovative projects that drive sustainable energy solu...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$150K - $238K *

Shape the future of digital manufacturing by leading strategic IT and operations initiatives. Drive multi-site transformation, ensuring seamless integration of technology and processes to enhance effi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$155K - $160K *

Drive the Order-to-Cash strategy, overseeing cash application, collections, and AR performance. Collaborate cross-functionally to optimize cash flow and enhance financial reporting, ensuring timely re...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Join a dynamic team as you optimize recipe and task build solutions, driving operational excellence and standardization. Collaborate across departments to enhance workflows and implement scalable proc...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Technical Services

$120K - $145K *

Shape the future of water and wastewater systems by leading projects from planning to optimization. Collaborate with diverse teams to deliver innovative solutions for municipal and industrial clients...

United StatesRemote

Today

  •   15+ years exp.  •   Technical Services

$156K - $220K *

Unlock your potential by leading the paid media strategy in a transformative role involving creative innovation and team development, driving growth through data-driven decisions across multiple chann...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Media

$65K - $116K *

Drive exceptional client experiences by leading delivery operations, managing relationships, and leveraging analytics to identify service gaps. Collaborate cross-functionally to ensure seamless execut...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$86K - $106K *

Drive advertiser growth by optimizing campaign performance and building strong client relationships. Collaborate with internal teams to enhance product offerings and ensure a seamless advertiser exper...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

$180K - $220K *

Shape the future of healthcare delivery by leading operations in denials resolution and payment compliance. Drive performance, quality, and financial outcomes while building a high-performing team and...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$159K - $168K *

Discover impactful opportunities by leading state and local government affairs in the Midwest, advocating for public policies that enhance community engagement and support the growth of a leading e-co...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.