Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$135K - $160K *

Lead data-driven strategies to enhance revenue growth across customer acquisition, retention, and expansion. Collaborate with cross-functional teams to establish integrated metrics and actionable insi...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$225K - $265K *

Shape the future of oncology by leading clinical studies in early-phase development. Collaborate with multidisciplinary teams to drive innovative therapies and ensure high-quality execution of clinica...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in optimizing fleet maintenance operations through strategic planning, data governance, and innovative automation. Drive results by enhancing system integration and building strong par...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$97K - $143K *

Innovate by leading electrical and electronics development projects, ensuring compliance with industry standards while mentoring engineers and driving product robustness through structured problem-sol...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$137K - $221K *

Empower innovation by designing and implementing core platform services for agent execution. Collaborate with cross-functional teams to build reliable APIs and workflows, ensuring robust performance a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$210K - $250K *

Lead the transformation of data and AI into business value, driving strategy, governance, and adoption across the organization. Collaborate with stakeholders to enhance analytics maturity and build a...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Finance & Insurance

$100K - $120K *

Transform payment strategies by analyzing interchange and routing data to optimize costs and enhance performance. Leverage advanced analytics and automation to deliver actionable insights for stakehol...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$79K - $116K *

Optimize project delivery by supporting large-scale warehouse automation deployments. Engage with cross-functional teams to track deliverables, manage risks, and maintain schedules, ensuring successfu...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$145K - $169K *

Transform the South Zone's beverage landscape by driving strategic growth, aligning stakeholders, and executing innovative plans that enhance market performance and profitability across a diverse Coca...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$232K - $320K *

Unlock potential by leading a dynamic Solutions Consulting team to deliver innovative cybersecurity solutions. Collaborate with sales and customers to ensure value realization and drive success in pre...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$67K - $93K *

Champion operational excellence by leading a warehouse team to ensure efficient, safe, and compliant receiving, storage, and shipping processes that support production goals and enhance overall perfor...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$80K - $95K *

Lead the design and delivery of impactful training programs, creating engaging learning materials and facilitating sessions to enhance employee skills and knowledge across various business units. Driv...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Empower your career by leading the Information Assurance program for critical Army systems. Oversee compliance, manage security processes, and collaborate with stakeholders to ensure robust cybersecur...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$108K - $155K *

Empower patient care by joining a dedicated team that provides telephonic support, addresses diverse medical and psychological needs, and enhances patient experiences while ensuring documentation accu...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $190K *

Drive innovation by architecting scalable AI solutions that transform business processes across multiple domains. Collaborate with leaders to establish enterprise standards and governance frameworks f...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$69K - $104K *

Unlock your potential by collaborating with leaders to enhance payor performance, streamline revenue cycle operations, and drive innovation in healthcare. Your expertise will ensure impactful engageme...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $231K *

Transform healthcare outcomes by leading a team of Clinical Program Consultants to analyze data, optimize clinical programs, and drive strategic initiatives that enhance customer health and reduce cos...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive technical solutions as a client-facing architect, leveraging deep expertise in JavaScript, TypeScript, and Python to guide enterprise-level projects across multiple cloud environments and enhanc...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Join a team that's pioneering AI-driven solutions, collaborating with clients to design and build innovative applications while leading technical initiatives and enhancing enterprise integrations...

Des Moines, IARemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$120K - $322K *

Elevate patient care by providing comprehensive psychiatric services in a dynamic correctional environment. Collaborate with a multidisciplinary team to develop treatment plans and ensure quality ment...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Unlock your potential by leading project procurement efforts, optimizing processes, and managing supplier relationships to enhance operational efficiency and profitability across diverse project categ...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$120K - $160K *

Join a team that's redefining integrated marketing strategies, leading cross-channel campaigns that drive product narratives and customer engagement. Shape the future of marketing through collaboratio...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$124K - $224K *

Unlock potential by leading revenue operations, bridging sales, finance, and analytics. Drive forecasting, pipeline management, and team development to enhance business performance and ensure data int...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$151K - $248K *

Unlock your potential by driving product innovation and cross-functional alignment in a dynamic environment. Lead initiatives that shape lending solutions, enhance decision-making, and deliver impactf...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$115K - $140K *

Empower your career by driving sales in a dynamic environment. As an Account Manager, leverage your expertise to promote our psychiatry portfolio, navigate market complexities, and build strong relati...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.