Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,696
$148K - $193K *
Develop and enhance business processes to optimize product lifecycle and data governance. Collaborate with cross-functional teams to drive operational consistency and improve decision-making through e...
Yesterday
Director, Clinical Development
$165K - $215K *
Empower innovation in ophthalmic device development by leading global clinical strategies for surgical programs, from feasibility to regulatory submissions. Collaborate cross-functionally to drive pro...
Reposted yesterday
$175K - $200K *
Champion strategic growth and account management with top-tier National Accounts. Lead a team towards innovative solutions, driving revenue and market impact while collaborating across departments for...
Reposted yesterday
$80K - $90K *
Lead the charge in cultivating partnerships with Travel Advisors across the Northeast, driving business growth through relationship-building and strategic outreach in the European travel market...
Yesterday
$94K - $266K *
Empower customer success by designing and implementing AWS Connect solutions, conducting technology assessments, and leading project communications to enhance contact center operations and agent produ...
Yesterday
$95K - $115K *
Champion the submission of high-quality federal proposals, managing the entire lifecycle from capture to delivery. Collaborate across teams to align strategies, ensuring compliance and compelling cont...
Reposted yesterday
$135K - $145K *
Lead the charge in innovative healthcare advertising by directing art and design for HCP campaigns. Collaborate with creative teams to transform scientific information into impactful visuals, ensuring...
Yesterday
Manager, Product Development - Home Appliances
$95K - $115K *
Lead product development for small household appliances, driving innovation from concept to launch. Collaborate with cross-functional teams, mentor junior engineers, and leverage AI tools to enhance d...
Reposted yesterday
Trade Compliance Sr. Professional
$95K - $115K *
Empower compliance excellence by monitoring U.S. trade laws, implementing export controls, and ensuring customs alignment. Collaborate cross-functionally to provide insights, support business units, a...
Reposted yesterday
Director of Development, Duke Heart Center and Cardiology
$79K - $159K *
Engage as a strategic partner in fundraising, developing and executing major gift strategies to support clinical programs and philanthropy within a complex academic medical environment, fostering rela...
Reposted yesterday
$101K - $164K *
Join a dynamic research team as a Biostatistician III, where you'll lead statistical analysis and consultation for diverse nursing studies, enhancing healthcare outcomes and population health while co...
Reposted yesterday
$80K - $95K *
Unlock potential by leading agile teams to maximize value delivery, coaching on Scrum principles, and facilitating continuous improvement. Collaborate with stakeholders to prioritize backlogs and enha...
Reposted yesterday
Assistant Manager, Capital Projects (For Hire Only)
$67K - $106K *
Help us transform ideas into sustainable spaces by managing capital projects that enhance education, research, and healthcare. Collaborate with diverse stakeholders to ensure projects align with insti...
Reposted yesterday
Senior Director, Business Operations and Performance, Supply Chain Management
$121K - $242K *
Transform operational excellence by leading AI-driven Supply Chain innovations, enhancing decision-making, and driving analytics for measurable impact across diverse initiatives in a complex, dynamic...
Reposted yesterday
$63K - $109K *
Optimize facility operations by leading a dedicated team, managing resources, and driving continuous improvement initiatives to enhance service delivery and operational efficiency across campus enviro...
Yesterday
$85K - $94K *
Partner with us to transform enterprise communication solutions through migrating to Microsoft Teams Voice. You'll drive technical initiatives, support voice infrastructure, and optimize services to e...
Reposted yesterday
$95K - $115K *
Engage as a key finance leader to enhance manufacturing cost accuracy, partner with operations, and drive profitability improvements while ensuring compliance and effective financial reporting within...
Reposted yesterday
$113K - $226K *
Lead strategic financial initiatives, ensure robust fiscal management, and enhance budgeting and reporting processes within a dynamic organization to support advanced educational and operational goals...
Reposted yesterday
Management Engineer- Duke Raleigh Campus
$85K - $100K *
Join us to empower performance management and improvement initiatives across our healthcare system, ensuring quality patient care through data analysis, project management, and collaboration with oper...
Reposted yesterday
$67K - $102K *
Champion compliance and quality assurance in GMP cellular product manufacturing. Collaborate with teams to ensure adherence to FDA regulations and FACT standards, driving process improvements and supp...
Reposted yesterday
Manager, Respiratory Therapy - Pediatrics
$88K - $105K *
Elevate patient care by leading clinical operations, ensuring compliance, and fostering team excellence in cardiopulmonary services while driving strategic improvements to enhance service quality and...
Reposted yesterday
$61K - $101K *
Unlock your potential by managing complex clinical research studies. Collaborate with multidisciplinary teams to ensure compliance, data integrity, and participant engagement while driving innovative...
Reposted yesterday
Sr Analyst, IT - SAP HR Developer
$95K - $115K *
Champion innovative SAP HR solutions by analyzing processes and developing high-performing applications. Collaborate with stakeholders to enhance technology and drive efficiency in HR systems, ensurin...
Reposted yesterday
Nurse Manager, Operations (NMO) - Cardiology & Pulmonary Clinic
$90K - $105K *
Join a team that's dedicated to advancing health through effective management and delivery of patient care in a dynamic clinical environment. Embrace a role that champions staff collaboration and opti...
Reposted yesterday
$95K - $115K *
Innovate enhanced analytical solutions that drive business value by transforming complex requests into actionable strategies and stakeholder alignment, ensuring effective collaboration across technica...
Reposted yesterday
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.