Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,696

Sort By: Relevance

$105K - $145K *

Elevate your career by designing and developing controls architecture for automated systems. Collaborate with cross-functional teams to deliver high-performance solutions, while ensuring compliance wi...

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$81K - $112K *

Shape the future of fiber optics by designing and automating optical test systems. Collaborate to ensure compliance with industry standards, validating performance while driving technical excellence a...

Reposted yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$94K - $129K *

Lead the charge in enhancing manufacturing control systems and operational technology. Collaborate with cross-functional teams to ensure seamless integration and reliability of plant-floor equipment w...

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$126K - $173K *

Join us to lead a dynamic team of Engineers and Technicians in a fast-paced manufacturing environment, driving product quality, safety, and cost reduction while fostering innovation and collaboration...

Reposted yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$72K - $100K *

Join a team that's redefining optical cable manufacturing by developing innovative processes and solutions. Collaborate with engineers to enhance production efficiency and drive customer value through...

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $123K *

Lead the charge in pharmaceutical meetings operations, driving client partnerships and operational excellence while navigating compliance. Shape processes and enhance stakeholder engagement to deliver...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Transportation

$126K - $173K *

Join us to lead market intelligence efforts, analyzing competitive dynamics and delivering insights that shape strategic decisions in the Optical Communications sector. Collaborate with cross-function...

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$97K - $133K *

Join a team that's dedicated to enhancing manufacturing processes and capabilities. As a Senior Manufacturing Engineer, you'll lead projects that drive cost reduction and process improvement, collabor...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $232K *

Lead transformative SAP solutions in manufacturing, optimizing processes and driving innovation. Collaborate with teams to deliver value-driven results, leveraging deep expertise in SAP S/4HANA and bu...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Join a team that's driving innovative demand generation strategies. You'll lead integrated campaigns, collaborate across departments, and optimize performance to generate qualified leads and pipeline...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$107K - $192K *

Unlock potential by leading multi-discipline teams in designing advanced instrumentation and control systems for nuclear power plants, ensuring safety and compliance while mentoring junior engineers a...

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Transform procurement operations by leading a strategic team to enhance compliance, efficiency, and value across institutional spending while navigating regulatory frameworks and fostering stakeholder...

Reposted yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$94K - $133K *

Unlock potential by managing and enhancing partnerships within the Technology Partner Community, guiding software partners through onboarding and integration processes to maximize the value of HCM and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Consumer Technology

$131K - $240K *

Shape the future of training and development in orthopedic medical devices, enhancing sales effectiveness and fostering strong partnerships across teams. Drive learning initiatives and support surgica...

RemoteRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Healthcare

$100K - $130K *

Champion compliance excellence by leading training and communication initiatives that enhance understanding and adherence to policies across the organization. Drive engagement and elevate the complian...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform strategic cybersecurity and infrastructure initiatives into actionable programs, ensuring effective governance and delivery across complex environments. Drive outcomes through meticulous pla...

Reposted yesterday

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Join a team that's transforming healthcare through strategic perioperative implementations. Lead complex, multi-site projects, engage with executives, and drive adoption of innovative solutions to enh...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$82K - $150K *

Accelerate growth by driving new customer acquisition and expanding market share in the dental implant sector. Leverage your sales expertise to build relationships, convert competitive accounts, and p...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$190K - $225K *

Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$82K - $150K *

Join a team that's driving growth in the dental implant market by aggressively prospecting and converting new customers. Leverage your sales expertise to expand market share and position value-oriente...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$190K - $225K *

Transform relationships with key opinion leaders in rare neurological diseases, providing strategic insights and guidance to inform brand strategies and enhance engagement across medical and commercia...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance operational excellence by leading large-scale initiatives across multi-site manufacturing. Collaborate effectively with cross-functional teams to achieve strategic goals and drive sustainable...

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$64K - $96K *

Drive strategic leadership in academic and workforce programs, ensuring alignment with institutional goals. Foster student success through innovative pathways and collaboration, while managing resourc...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join a team that's shaping the future of highway design through innovative engineering. Lead projects, mentor talent, and ensure quality while collaborating across disciplines to deliver state-of-the...

Reposted yesterday

  •   11 - 15 years exp.  •   Real Estate & Construction

$110K - $130K *

Champion regulatory compliance and lead a dynamic team in air program development. Drive initiatives, foster stakeholder relationships, and provide technical guidance to ensure effective air pollution...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.