Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,696
Manager, FSA (Feasibility Site Activation)
$95K - $115K *
Lead the charge in managing feasibility assessments and site activation for global clinical trials, ensuring timely delivery and high-quality outcomes while developing team capabilities and driving co...
Yesterday
Manager, FSA (Feasibility Site Activation)
$95K - $115K *
Join a team that's dedicated to optimizing site activation and feasibility assessments for global clinical trials, ensuring timely delivery and high-quality outcomes while fostering team development a...
Yesterday
Manager, FSA (Feasibility Site Activation)
$95K - $115K *
Transform clinical trial success by leading feasibility assessments and site activation teams. Drive operational excellence, manage resources, and foster team development to ensure timely project deli...
Yesterday
Manager, FSA (Feasibility Site Activation)
$95K - $115K *
Lead the charge in delivering high-quality feasibility assessments and site activation for global clinical trials, managing teams to ensure operational success and continuous improvement in a dynamic...
Yesterday
Manager, FSA (Feasibility Site Activation)
$88K - $105K *
Join a team that's dedicated to delivering high-quality feasibility assessments and efficient site activation for global clinical trials, while fostering team development and driving continuous improv...
Yesterday
$115K - $135K *
Join a team that's driving enterprise growth by identifying new business opportunities and forming strategic relationships. You'll navigate complex sales cycles and engage with senior leaders to tailo...
Reposted yesterday
Senior Segment Marketing Manager
$110K - $130K *
Drive integrated marketing strategies for Enterprise accounts, enhancing engagement and pipeline growth. Collaborate with sales teams to execute targeted campaigns and impactful events, optimizing per...
Yesterday
MTF LAN/WLAN Infrastructure Technician
$72K - $87K *
Champion the design and installation of advanced telecommunications systems, ensuring optimal performance and compliance. Collaborate on-site to enhance infrastructure for medium to large-scale projec...
Yesterday
$110K - $130K *
Champion the delivery of large-scale data center projects, overseeing field operations, client coordination, and compliance across multiple sites. Drive project success through effective management of...
Yesterday
Senior Financial Analyst (Consolidation)
$100K - $120K *
Lead the consolidation of financial models and metrics, partnering with cross-functional teams to deliver actionable insights and support strategic decision-making across the organization...
Yesterday
Senior Technology Operations Manager
$115K - $151K *
Transform technology operations by leading financial management, procurement, vendor oversight, and asset management. Drive strategic decision-making and operational excellence to enhance service deli...
Yesterday
Senior Client Services Lead - Indigenous Relations
$106K - $149K *
Help us advance Indigenous Relations by building partnerships with Tribal communities and clients. Lead strategic initiatives, mentor staff, and drive excellence in consultation services across divers...
Yesterday
Staff/ Principal Software Engineer (L6/L7): AI Platform Model Serving
$500K+*
Join a team that's redefining AI/ML model serving infrastructure at scale. Lead innovative solutions for real-time and async workloads, optimizing GPU utilization while embedding AI capabilities into...
Yesterday
Customer Service Analytics & Insights Analyst
$150K - $230K *
Drive insights and forecasting for Customer Service by analyzing demand patterns and customer interactions. Collaborate with teams to enhance operational efficiency and improve customer experience thr...
Yesterday
Senior Creative Technologist, Games GenAI
$250K - $370K *
Transform game development by leveraging generative AI to create engaging prototypes. Collaborate across teams to shape visual style, narrative, and sound, ensuring innovative concepts evolve into fun...
Yesterday
Software Engineer 6 - Feature Infrastructure
$500K+*
Unlock potential by building a next-gen ML data platform that enhances productivity for ML practitioners. Collaborate with experts to create scalable infrastructure for feature computation and sharing...
Yesterday
Lead Analyst Digital Accelerator
$96K - $135K *
Champion process automation and enhancements by leading investment initiatives, mentoring teams, and collaborating across departments to drive efficiency and continuous improvement in investment servi...
Yesterday
Director, Franchise Performance & Activation, Core Performance
$163K - $192K *
Lead the charge in enhancing hotel performance and franchisee support by managing teams, driving operational excellence, and activating commercial strategies across the Core portfolio, ensuring alignm...
Yesterday
Program Management Specialist, Product Marketing & GTM Operations
$95K - $115K *
Shape the future of product marketing by driving operational excellence in product launches and go-to-market initiatives. Collaborate across teams to ensure seamless execution and strategic alignment...
Reposted yesterday
Senior Director, Integrated Campaigns
$160K - $190K *
Advance integrated marketing strategies by leading global campaigns that drive engagement, pipeline generation, and customer retention. Collaborate cross-functionally to optimize messaging and deliver...
Yesterday
Professional (Senior) Sales Representative, Pain - Philadelphia, PA
$100K - $162K *
Join us to develop strategic business plans and conduct effective sales presentations while achieving goals in the pharmaceutical territory. Build relationships, influence key stakeholders, and drive...
Reposted yesterday
Professional (Senior) Sales Representative, Respiratory – Cape Coral, FL
$100K - $162K *
Engage with healthcare professionals to drive sales growth in the Cape Coral territory. Develop strategic business plans, conduct impactful presentations, and foster strong relationships while adherin...
Yesterday
$200K - $250K *
Empower clients by guiding them through mortgage options and ensuring seamless application processes. Collaborate with internal teams to meet customer needs while maintaining high standards of service...
Yesterday
Demand Side Management Analyst
$80K - $95K *
Analyze energy efficiency and demand response programs while collaborating with a diverse team. Utilize data analysis to provide insights, recommendations, and drive improvements for utilities across...
Reposted yesterday
$111K - $160K *
Transform category growth by leveraging insights and strategies to enhance customer performance. Collaborate cross-functionally to optimize assortments and drive sales initiatives across diverse retai...
Reposted yesterday
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.