Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,696

Sort By: Relevance

$110K - $130K *

Unlock your potential as a Senior Divisional Risk Advisor, shaping risk strategy and fostering a risk-smart culture in retirement services. Collaborate with leaders to enhance controls and ensure comp...

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Manage the development of AI orchestration platforms and shared infrastructure, delivering production-ready GenAI solutions by collaborating effectively with product and engineering teams while ensuri...

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  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Shape the future of network security by leading a dynamic team, implementing Zero Trust architectures, and driving continuous improvement across cloud and on-prem technologies to enhance secure access...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$94K - $135K *

Shape the future of implementation by leading a dynamic team to ensure successful project execution, stakeholder engagement, and quality outcomes in a fast-paced environment...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$63K - $108K *

Engage in leading large, complex projects by managing scope, resources, and budgets. Collaborate with stakeholders, develop project proposals, and ensure effective communication across teams to drive...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Shape the future of customer engagement by leading strategic sales and support initiatives. Drive growth, enhance customer satisfaction, and foster partnerships while overseeing a high-performing team...

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  •   8 - 10 years exp.  •   Transportation

$100K - $150K *

Transform patient care by leveraging multimodal AI models in a hands-on role. Collaborate with life sciences to innovate solutions, ensuring regulatory compliance while contributing to impactful resea...

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Champion the adoption of MRD testing services by engaging clinicians and stakeholders, driving strategic business development, and maximizing client relationships within major cancer centers and healt...

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $178K *

Transform the cybersecurity landscape by implementing and managing enterprise security technologies. Collaborate across teams to enhance security architecture, mitigate risks, and support innovative s...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $178K *

Advance your career by architecting identity governance solutions, managing user privileges, and integrating security technologies to enhance organizational identity management and compliance...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$102K - $134K *

Join a team that's redefining project estimating by leading the preparation of competitive bids and cost analyses for electrical construction projects. Collaborate with estimators and suppliers to ens...

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Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$117K - $154K *

Elevate your career by providing senior-level technical support and oversight for complex electrical power systems. Collaborate with project managers and site teams to ensure compliance with design sp...

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$80K - $100K *

Support a diverse team in delivering exceptional field service for high-tech vacuum products. Engage with customers, troubleshoot systems, and ensure operational excellence while traveling for install...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$128K - $225K *

Unlock potential by leading cloud engineering strategy and product development. Oversee a high-performing team to deliver secure, scalable cloud solutions across multiple providers, ensuring alignment...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$71K - $118K *

Advance your career by analyzing and responding to cyber incidents in a dynamic 24x7 Security Operations Center, supporting U.S. State, Local, Tribal, and Territorial governments with critical securit...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$131K - $209K *

Engage with teams to deliver comprehensive AI enablement programs, designing tailored learning paths and fostering a culture of proficiency across all departments. Collaborate closely with HR to integ...

United StatesRemote

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  •   Less than 5 years exp.  •   Information Technology

$71K - $113K *

Drive impactful investigations into fraud alerts and suspicious activities. Collaborate with internal teams and law enforcement to protect assets and mitigate risks, ensuring compliance with regulatio...

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  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's dedicated to advancing aerospace technologies by applying your materials engineering expertise to sustain and innovate critical aerospace products, ensuring quality and reliability...

Today

  •   Less than 5 years exp.  •   Technical Services

$125K - $150K *

Elevate HR leadership by driving people strategies that enhance organizational effectiveness and employee engagement across multiple locations in the North America Industrial & Construction sector, pa...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Transportation

$135K - $160K *

Lead the charge in building a unified technical organization that enhances customer experience through application support and field service, driving project conversions and fostering a culture of con...

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  •   8 - 10 years exp.  •   Manufacturing & Automotive

$189K - $255K *

Drive strategic sales initiatives by developing account plans, fostering C-level relationships, and leading negotiations to maximize customer success and revenue growth across a diverse product portfo...

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  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Accelerate client relationships by managing strategic accounts, driving revenue growth, and expanding service lines. Collaborate with internal teams to ensure client satisfaction and deliver tailored...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$125K - $150K *

Accelerate account management strategy and execution for premier accounts. Strengthen relationships through planning, product penetration, and high-quality execution while collaborating across teams t...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $95K *

Empower your career by overseeing clinical operations and managing personnel in a dynamic healthcare environment. Drive excellence in service delivery while ensuring compliance with regulatory standar...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$105K - $163K *

Empower AI seeks to optimize ITSM solutions by leading ServiceNow development for a Department of War agency. Drive high-quality, secure applications while enhancing user experience through Agile meth...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.