Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,788
SIGINT Analyst- Subject Matter Expert
$97K - $132K *
Transform intelligence operations by leveraging your SIGINT expertise to guide strategic initiatives, enhance analytical capabilities, and support mission-critical objectives within a dynamic environm...
1 week ago
RN Clinical Nurse IV - Acute Neurosurgery & ENT Night Shift
$80K - $122K *
Lead the charge in delivering expert nursing care for complex neurosurgery and ENT patients. Collaborate with a dynamic team to enhance clinical practices and foster professional development in a supp...
1 week ago
RN Field Nurse Advanced Care at Home - Command Center
$71K - $100K *
Advance your nursing career by providing in-home clinical care, collaborating with interdisciplinary teams, and ensuring patient-centered outcomes in a dynamic healthcare environment...
1 week ago
RN Clinical Nurse II- GI Surgery & Surgical Oncology Acute Care/ 6 Memorial
$71K - $100K *
Join a team that empowers patient care through skilled nursing in a dynamic acute care setting. Deliver high-quality, evidence-based nursing services to post-surgical patients, ensuring comprehensive...
1 week ago
$74K - $107K *
Champion patient recovery by delivering expert occupational therapy in a dynamic acute care setting. Collaborate with a multidisciplinary team to enhance patient outcomes and support effective dischar...
1 week ago
RN Clinical Nurse II - Lactation Services
$71K - $100K *
Join a dedicated team providing expert lactation support for critically ill infants. Collaborate with healthcare professionals to empower families and enhance feeding outcomes in a dynamic, interdisci...
1 week ago
RN Clinical Nurse II - UNC MPS Clinic
$71K - $100K *
Join a team that's dedicated to delivering exceptional pediatric nursing care. You'll coordinate and implement patient care plans, ensuring high standards while collaborating with interdisciplinary te...
1 week ago
RN Clinical Nurse II - Pediatric Cardiac ICU (Acute Care)
$71K - $100K *
Elevate your nursing career by providing specialized care for pediatric cardiac patients. Gain cross-training in diverse medical cases while enhancing your clinical skills in a dynamic, high-acuity en...
1 week ago
RN Clinical Nurse II - Oncology Infusion, Cary
$71K - $100K *
Join a team that's dedicated to providing compassionate oncology care. As a Clinical Nurse, you'll coordinate and deliver patient care, ensuring high standards in a supportive environment focused on p...
1 week ago
SAP AI Transformation - Senior Consultant - SAP Supply Chain
$110K - $218K *
Innovate SAP Supply Chain solutions by leveraging AI and ERP expertise to drive transformative client outcomes. Collaborate with cross-functional teams to enhance business processes and support autono...
1 week ago
Sr. Subcontract Administrator (Remote)
$88K - $154K *
Transform subcontracting processes by managing proposals, contracts, and vendor relationships. Leverage your expertise to ensure compliance and efficiency while guiding a team in a dynamic, remote env...
1 week ago
Manufacturing Project Engineer
$80K - $95K *
Elevate manufacturing excellence by leading project engineering efforts for new model launches. Collaborate cross-functionally to ensure timely execution and production readiness in a dynamic automoti...
1 week ago
Clinical Research Associate II
$120K - $145K *
Lead the charge in overseeing clinical trials, ensuring compliance with protocols and regulations while safeguarding patient welfare and contributing to the development of lifesaving treatments...
1 week ago
Head of Immunology, Portfolio Manager - 176578
$270K - $360K *
Reimagine global clinical development by leading strategic oversight across Immunology and Infectious Disease portfolios, driving client partnerships and business growth while ensuring organizational...
1 week ago
$95K - $115K *
Unlock potential by designing and implementing innovative workflow automations that enhance efficiency across various business functions, collaborating with cross-functional teams to transform manual...
Reposted 1 week ago
Associate Director, Strategic Accounts (New England)
$135K - $160K *
Unlock potential by leading a dynamic sales team in hematology, driving strategic account management and fostering key stakeholder relationships to enhance the clinical experience with ZYNLONTA across...
1 week ago
Litigation Fellowship, Environment & Natural Resources (Fall 2027)
$100K *
Champion liberty and defend individual rights as you engage in impactful public-interest law through a dynamic year-long fellowship, working alongside experienced attorneys on crucial environmental ca...
Reposted 1 week ago
Product Marketing Director, Velocity
$200K - $371K *
Drive go-to-market strategy for SMB and Mid-Market segments, leading cross-functional initiatives to enhance customer engagement, positioning, and revenue growth, while establishing best practices for...
Reposted 1 week ago
Program Director, Employee Relations
$121K - $190K *
Transform employee relations by building a robust ER model, leading complex investigations, and empowering HR teams. Drive strategic initiatives while managing sensitive employee matters to create eff...
1 week ago
Vendor Governance & Controls Analyst
$89K - $143K *
Drive vendor governance excellence by coaching stakeholders, enforcing accountability, and facilitating training. Ensure compliance with vendor management policies while fostering a culture of continu...
1 week ago
Senior Manager, Finance Operations
$110K - $130K *
Manage and oversee finance operations, leading accounts payable and billing functions across multiple regions. Ensure accuracy and compliance in procure-to-pay and order-to-cash processes while buildi...
1 week ago
Customer Experience Program Manager - West Region
$122K - $152K *
Shape the future of customer experience by leading regional operations, driving strategic initiatives, and enhancing service delivery. Collaborate with cross-functional teams to achieve operational ex...
1 week ago
Senior Electrical Physical Wiring Designer 1 - Nuclear Power
$77K - $118K *
Elevate your drafting career by collaborating in a dynamic team, utilizing advanced CAD tools, and gaining hands-on experience in 3D design. Contribute to innovative projects that shape the future of...
1 week ago
$87K - $108K *
Join a dynamic engineering team to deliver innovative electrical solutions. Collaborate on complex projects, mentor junior staff, and ensure compliance with industry standards while driving quality an...
Reposted 1 week ago
$87K - $108K *
Transform partner marketing strategies by executing joint initiatives with Google, enhancing visibility and demand for digital innovations. Collaborate across teams to drive growth and optimize market...
Reposted 1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.