Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,816

Sort By: Relevance

$115K - $173K *

Empower your career by managing complex loan workouts, negotiating terms, and guiding teams. Utilize your expertise in financial analysis and communication to drive successful outcomes for challenging...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$79K - $127K *

Lead the charge in developing innovative Salesforce solutions that drive analytics and support business objectives. Collaborate with teams to deliver high-quality applications while ensuring alignment...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$190K *

Optimize engineering services by leading DevOps and SRE teams, enhancing CI/CD processes, and ensuring data governance. Drive operational excellence and security while fostering a collaborative enviro...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$275K - $330K *

Transform cloud services architecture and lead innovative design initiatives. As a Principal Engineer, you'll drive technical direction, optimize data models, and mentor teams to enhance software deli...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$80K - $133K *

Innovate with us to deliver AI and machine learning solutions that transform data into actionable insights. Collaborate across teams to enhance fraud detection and anomaly analysis, leveraging advance...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$113K - $188K *

Transform data into insights by developing cutting-edge machine learning models. Collaborate with multidisciplinary teams to address complex business needs using advanced analytics, ensuring data-driv...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$130K - $216K *

Transform enterprise Databricks environments with innovative designs, ensuring secure, efficient implementations while collaborating with stakeholders to deliver scalable data solutions and enhance go...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$89K - $148K *

Champion change management during EHR implementation, guiding users through training and support, while fostering stakeholder relationships to align with program objectives and enhance workflow for a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$45K - $250K *

Transform your career by connecting healthcare professionals with meaningful roles. Join a supportive team focused on building relationships and driving results while enjoying unlimited earning potent...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Accelerate engineering productivity by designing and enhancing enterprise automation and DevSecOps platforms. Drive innovation with AI, build reusable frameworks, and improve scalability to transform...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the execution of high-impact cross-functional initiatives as a Senior Infrastructure Engineer, ensuring technical delivery and alignment across diverse teams, including engineering and compliance...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Drive innovation in enterprise automation by designing and enhancing CI/CD platforms, leveraging AI and intelligent automation to improve software delivery and operational excellence across the organi...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Champion a transformative Advice & Planning strategy, enhancing team capabilities and client impact through innovative processes and seamless integration. Drive excellence in execution and foster a le...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Drive strategic initiatives within Fraud Product and Operations, leading teams to optimize efficiency and enhance client experiences while managing compliance and operational risks. Foster talent deve...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Unlock potential by leading the deployment and support of cutting-edge robotic solutions. Manage logistics, field operations, and service excellence while ensuring safety and compliance across diverse...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $145K *

Unlock potential by leading product strategy and innovation across complex omnichannel personalization initiatives. Drive product success through collaboration, data-driven decisions, and a focus on u...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Shape the future of pricing strategies by leading holistic initiatives that drive growth and profitability. Collaborate with cross-functional teams to optimize pricing decisions and enhance customer v...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$153K - $166K *

Join a team that's shaping the future of AI governance in software development. As a Senior Engineer, you'll design policies and tools that ensure safe, effective use of AI coding agents, empowering d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$104K - $155K *

Lead and innovate in AP Test Publishing, overseeing print exam production and vendor collaboration to ensure equitable access and high-quality materials for students worldwide. Drive strategic plannin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$104K - $160K *

Champion integrity in assessment operations by leading a team to resolve testing irregularities and enhance automated processes, ensuring equitable testing experiences for all students while driving s...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$76K - $120K *

Take ownership of critical operational pipelines as a Research Statistician, executing analyses and improving processes to ensure the SAT Suite runs smoothly. Collaborate with cross-functional teams t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $190K *

Transform Global Medical Affairs by leading operations and analytics, ensuring strategic alignment and data-driven decisions. Drive excellence across teams, manage budgets, and foster collaboration to...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Collaborate with executives to lead full-cycle executive recruitment, develop search strategies, and enhance candidate experiences while utilizing data-driven insights to optimize talent acquisition p...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Transportation

$152K - $228K *

Grow your career with a dynamic role focused on expanding IgAN in nephrology. Build relationships with healthcare professionals, drive sales, and implement strategic business plans to enhance patient...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Join our team as a Regional Account Manager, where you'll drive growth in nephrology by building relationships with healthcare professionals and executing strategic business plans to support our innov...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.