Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,677

Sort By: Relevance

$95K - $115K *

Lead cross-functional teams to optimize civil engineering projects, ensuring compliance and innovative solutions from inception to completion. Collaborate with experts to enhance infrastructure design...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$95K - $115K *

Unlock your potential by leading mechanical simulations and structural analysis. Collaborate across teams to enhance product development, ensuring quality and efficiency in manufacturing processes whi...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Transform your career by leading innovative civil engineering projects. Collaborate with experts to enhance infrastructure design and execution while mentoring junior team members in a dynamic, team-f...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$125K - $150K *

Lead the charge in overseeing facility operations, EHS compliance, and capital projects to enhance a multi-building campus, driving operational excellence and a customer-focused culture while ensuring...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Join a team that's redefining audit and advisory services by driving full-cycle sales of an innovative AI platform. Collaborate with CPA firms to foster relationships and guide them through a transfor...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$192K - $338K *

Champion new business growth by leveraging your Private Equity expertise to drive AI-led transformation. Own the sales cycle from prospecting to contract closure, ensuring tailored solutions that deli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $243K *

Deliver innovative disaster recovery solutions for healthcare systems, ensuring compliance and resilience for clinical workloads. Collaborate with cross-functional teams to address complex challenges...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Drive the full sales cycle for fintech solutions, engaging SMEs across various sectors. Leverage your expertise to exceed revenue targets while ensuring exceptional customer onboarding and success in...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $130K *

Join us to drive data migration and integration initiatives for Higher Education clients, focusing on Advancement systems. Leverage your SQL and Salesforce expertise to ensure data accuracy and succes...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Drive growth in the Direct to Fabric market by identifying new accounts, executing sales strategies, and fostering customer relationships to enhance profitability and market presence...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$186K - $311K *

Join a team that's redefining analytics in the pharmaceutical industry. Lead the development and deployment of AI-driven methods that transform data into actionable commercial insights, ensuring scien...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$206K - $267K *

Transform your career by leading innovative architectural strategies and governance. As a trusted advisor, you will drive technology alignment and maximize investments while mentoring cross-functional...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Transportation

$110K - $130K *

Optimize your career by driving website growth and conversion strategies. Lead initiatives to enhance user experience, analyze performance metrics, and collaborate cross-functionally to achieve impact...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$155K - $210K *

Lead a dynamic team to drive strategic growth and profitability across a portfolio of key accounts, fostering strong partnerships and aligning cross-divisional strategies to enhance customer experienc...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $235K *

Unlock potential by driving scientific excellence as a strategic partner, educating healthcare professionals on Immuno-Oncology and fostering relationships that support cancer therapeutic initiatives...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $150K *

Elevate your career by leading strategic initiatives in the data center market, driving project success, and mentoring teams to deliver high-quality, profitable solutions for mission-critical clients...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $230K *

Grow your career with a dynamic team focused on oncology solutions, driving product promotion and building relationships with key stakeholders to enhance patient access and care in a competitive bioph...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Unlock your potential by driving oncology product success through strategic relationships and innovative solutions. Collaborate with key stakeholders to enhance patient access and exceed performance g...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Help us drive oncology product success by building relationships with key stakeholders, promoting innovative therapies, and ensuring patient access while exceeding performance goals in a dynamic bioph...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Elevate patient care by driving oncology product success through strategic relationships and innovative solutions. Lead efforts in territory management, market analysis, and collaborative engagement t...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$89K - $125K *

Lead the charge in driving strategic growth for the Walmart account by leveraging advanced analytics and shopper insights to optimize category performance and enhance buyer partnerships across retail...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$68K - $93K *

Drive sales growth by developing relationships with veterinary practices, utilizing digital marketing and CRM tools to enhance customer engagement and achieve sales targets in a dynamic inside sales e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape financial strategy by providing expert analysis and guidance in technology and operations. Drive critical decision-making around product development, forecasting, and performance evaluation whil...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a dynamic team driving financial analysis and guidance for strategic decisions. Utilize your expertise to develop forecasts, lead performance evaluations, and mentor analysts while ensuring compl...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Lead the drive for innovation in gas turbine combustion manufacturing, enhancing productivity and ensuring effective collaboration with diverse teams for new product introduction and continuous proces...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.