Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,677

Sort By: Relevance

$150K - $230K *

Optimize your career by driving oncology product success and building impactful relationships with healthcare professionals. Leverage your expertise to enhance patient access and deliver innovative so...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance agricultural procurement strategies by leading sourcing, building supplier relationships, and managing budgets to ensure quality and cost-effectiveness in sourcing cucumbers, peppers, and othe...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$150K - $230K *

Join a team that's dedicated to advancing oncology care by promoting innovative treatments, building strong relationships with healthcare professionals, and driving patient access to essential therapi...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Shape the future of commercial law by leading negotiations and advising on product launches. Collaborate with cross-functional teams to enhance legal processes and support strategic growth initiatives...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$149K - $173K *

Lead quality and food safety initiatives across North America, ensuring compliance and audit readiness. Drive continuous improvement and operational excellence through technical expertise and collabor...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$88K - $105K *

Help us drive innovation by collaborating on software design, coding, and testing. You'll enhance system reliability and support teams through the entire SDLC, ensuring high-quality software solutions...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$250K - $300K *

Unlock the potential of patient care by leading clinical management in head and neck oncology. Collaborate with a multidisciplinary team to advance research, and mentor the next generation of oncologi...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Unlock potential by joining a dynamic team that drives software solutions through collaboration, coding, and quality assurance. Contribute to all SDLC phases while enhancing system reliability and use...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$83K - $103K *

Drive success in regulatory affairs by preparing critical submissions for medical and diagnostic devices. Oversee compliance with U.S. and international regulations while collaborating with cross-func...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K *

Contribute to high-impact proposal development by crafting persuasive narratives that align with client needs and competitive positioning, ensuring compliance and strategic messaging throughout the pr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$155K - $190K *

Manage the planning and execution of CMC operations across multiple development programs, ensuring alignment with regulatory milestones and efficient collaboration with cross-functional teams and CDMO...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Serve as a strategic HR partner, guiding leaders and employees through employee relations, performance management, and compliance across multiple departments in a dynamic, remote environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $130K *

Join us to lead a clinical team as a BCBA, guiding treatment, mentoring RBTs, and enhancing care quality. Enjoy protected clinical time and operational support to focus on team development and learner...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Empower a clinical team by leading ABA programming, mentoring RBTs, and enhancing learner outcomes. Focus on individualized treatment, operational support, and fostering a collaborative clinic culture...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $185K *

Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$125K - $150K *

Design and manage scalable AWS cloud infrastructure, ensuring alignment with business goals while optimizing performance, security, and cost. Collaborate across teams to drive cloud migration and mode...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $160K *

Champion quality excellence by leading and standardizing assurance systems across regional logistics operations, driving continuous improvement and client partnerships while supporting new business la...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$224K - $326K *

Serve as a technical leader for large customers, guiding AI cloud strategies. Connect business priorities with scalable architecture while managing executive engagements and navigating complex decisio...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Lead the charge in delivering strategic and operational excellence across high-profile medical affairs accounts, fostering client relationships and guiding teams to achieve exceptional results in publ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $105K *

Join a team that's dedicated to delivering impactful medical communications. As a Senior Account Manager, you'll lead strategic projects for pharmaceutical clients, ensuring quality and timely executi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $212K *

Lead the design of a comprehensive Developer Portal, enhancing the developer experience through intuitive interfaces and impactful improvements. Collaborate with cross-functional teams to drive user-c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $95K *

Transform client relationships by leading strategic projects, ensuring quality and alignment across teams. Collaborate with stakeholders to drive success and meet client expectations while fostering g...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $240K *

Unlock potential by serving as a strategic technical advisor for key enterprise customers, guiding architecture decisions and aligning technical plans with business outcomes to ensure successful imple...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Unlock your potential by leading biostimulant strategies across North America. Collaborate with teams to drive product adoption, enhance profitability, and develop innovative solutions in the agricult...

United StatesRemote

1 week ago

  •   15+ years exp.  •   Manufacturing & Automotive

$185K - $231K *

Champion a transformative growth agenda for RTD & Convenience, focusing on channel expansion, strategic partnerships, and market leadership to drive profitability and market share while collaborating...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Food & Beverages

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.