Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,632

Sort By: Relevance

$201K - $251K *

Elevate access strategies and marketing initiatives for oncology products, focusing on non-clinical value propositions. Collaborate cross-functionally to ensure successful product launches and effecti...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$255K - $424K *

Lead the development and execution of Immunology access services strategy, ensuring seamless patient and provider experiences. Collaborate cross-functionally to enhance reimbursement initiatives and d...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $160K *

Champion privacy compliance in the Neurology therapeutic area, providing expert guidance on data protection, contract negotiation, and training. Collaborate with cross-functional teams to ensure adher...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Shape your career by managing client relationships and driving AI solutions in the automotive sector. Leverage your expertise in conversational AI and marketing automation to enhance performance metri...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$70K - $150K *

Drive growth in oral surgery practices by building relationships, pursuing new sales opportunities, and achieving targets. Leverage your sales expertise to deliver exceptional customer service and sup...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $500K *

Unlock potential by driving mortgage transactions with innovative technology and dedicated support. Leverage robust investor access for swift approvals and closings. Ideal for experienced professional...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$88K - $105K *

Drive impactful assessments by analyzing chemical data to enhance human health and environmental safety. Collaborate with stakeholders to develop regulatory strategies and communicate findings effecti...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Lead program operations and quality assurance for Hematopoietic Cell Transplant and Cellular Therapy, collaborating with multidisciplinary teams to achieve organizational objectives and ensure complia...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Innovate enterprise data architecture strategies, shaping design of secure, scalable cloud-native platforms that drive analytics, AI/ML, and data democratization while collaborating with cross-functio...

North Carolina, USRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Transportation

$80K - $110K *

Design and develop advanced analytics solutions, transforming complex healthcare data into actionable insights using Azure Databricks and Power BI. Collaborate with cross-functional teams to enhance r...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $114K *

Lead the charge in optimizing production efficiency and safety in a dynamic manufacturing environment. Drive continuous improvement initiatives while ensuring quality standards and financial goals are...

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$88K - $105K *

Optimize the Quality Control microbiology processes by supervising a team, ensuring compliance with cGMP, and driving continuous improvement in testing methods and environmental monitoring programs fo...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join us to minimize access barriers for patients and providers, executing market access plans across multiple states. Collaborate with healthcare professionals to resolve reimbursement issues and enha...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$68K - $118K *

Contribute to efficient order management by overseeing customer orders from acceptance to delivery. Collaborate across teams to ensure accurate data and timely resolutions, enhancing operational perfo...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$115K - $160K *

Deliver comprehensive primary care in long-term settings, fostering meaningful patient relationships and collaboration with interdisciplinary teams to enhance resident health outcomes...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $350K *

Join a team that's building scalable, high-performance backend systems using TypeScript. Collaborate across functions to optimize trading solutions and tackle complex challenges in the blockchain spac...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$77K - $95K *

Unlock potential by contributing your skills to impactful water and wastewater infrastructure projects. Collaborate with multidisciplinary teams while growing your career through diverse engineering c...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $145K *

Empower your career by leading the design and implementation of Oracle Field Service solutions for utility organizations. Collaborate with stakeholders to enhance operational performance and customer...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Staffing

$70K - $106K *

Transform operational data into actionable insights while collaborating with cross-functional teams to support business decisions and enhance efficiency. Leverage analytical skills to drive performanc...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Build a rewarding telehealth career by delivering patient-centered care across North Carolina. Enjoy flexible scheduling while managing diverse clinical cases through secure virtual consultations in a...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by overseeing a portfolio of enterprise accounts, fostering strategic partnerships, and driving user engagement to achieve measurable outcomes. Collaborate with internal teams to deli...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$210K *

Unlock your potential in telemedicine by delivering high-quality, patient-centered care across North Carolina. Enjoy flexible scheduling while managing diverse clinical cases through secure virtual co...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$227K - $335K *

Empower growth through strategic marketing leadership, leveraging data insights to drive customer engagement and revenue. Build and mentor a high-performing team to transform analytics into actionable...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Transportation

$155K - $259K *

Transform healthcare performance by leading integrated optimization programs that enhance clinical, operational, and financial outcomes for hospitals and health systems. Drive measurable results throu...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Shape the future of product design by transforming concepts into high-fidelity experiences. Collaborate with cross-functional teams to enhance user interactions through innovative prototyping and AI-a...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.