Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,632

Sort By: Relevance

$89K - $171K *

Innovate customer engagement by leveraging clinical expertise to drive product utilization and sales growth in a dynamic territory. Collaborate with healthcare professionals to navigate payer complexi...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $154K *

Champion the design verification and validation of embedded systems, leading test automation and laboratory activities for critical power products. Collaborate with cross-functional teams to ensure pr...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$106K - $171K *

Join a team that's advancing AI in contact center operations. Lead initiatives to integrate AI tools, enhance efficiency, and improve customer experiences while collaborating with business and technic...

3 days ago

  •   5 - 7 years exp.  •   Media

$100K - $300K *

Lead complex analytical initiatives by developing data solutions and dashboards that drive business insights. Collaborate with stakeholders to translate requirements into scalable analytical framework...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$190K - $220K *

Champion innovation and execution as you lead product management across diverse e-commerce channels. Drive strategic roadmaps, manage global teams, and deliver cutting-edge solutions that enhance cust...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$80K - $95K *

Join a dynamic team as a laboratory animal veterinarian, providing exceptional veterinary care, collaborating on research projects, and ensuring compliance with animal welfare standards in a fully acc...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Drive operational excellence at our manufacturing site by leading a dynamic team. Oversee productivity, cost management, quality systems, and safety compliance while fostering a culture of continuous...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$115K - $150K *

Innovate at the forefront of database management, ensuring performance, reliability, and security in a high-volume SQL Server environment. Lead incident response and engineering solutions to enhance o...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$156K - $227K *

Elevate executive compensation strategies by designing and leading Total Rewards programs that align with organizational goals, while collaborating with key stakeholders to ensure compliance and effec...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $160K *

Unlock potential by leading complex cyber investigations, mentoring junior analysts, and analyzing sophisticated threats to safeguard AI systems from misuse. Drive impactful decisions and enhance safe...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$144K - $211K *

Drive engineering excellence by leading a high-performing team in implementing and scaling industrial control systems. Collaborate across functions to ensure reliable, maintainable solutions that supp...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $160K *

Engineer the future of critical facility commissioning by leading project teams, managing schedules, and ensuring compliance with design and safety standards. Drive successful project execution throug...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$125K - $172K *

Drive your career forward as an Engineering Supervisor, leading a team to enhance equipment design and deployment. Focus on capacity expansion, efficiency improvements, and cost reduction while collab...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $229K *

Lead the design and development of AI-driven solutions within SAP S/4HANA, integrating advanced AI technologies to drive business transformation and innovation across enterprise environments. Mentor t...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$123K - $135K *

Engage with existing customer accounts to drive renewal retention and expansion revenue. This growth-focused role emphasizes consultative upselling and cross-selling, ensuring customer satisfaction wh...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $141K *

Join a team that's dedicated to providing expert bioinformatics support, bridging customer needs with innovative NGS solutions. You'll play a key role in pre- and post-sales activities, ensuring custo...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive exceptional service across multiple locations by leading teams to enhance customer satisfaction, boost technician productivity, and achieve revenue goals. Collaborate with store leadership to bu...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$95K - $185K *

Champion roadway design projects by managing scope, fees, and client relationships. Lead cross-functional teams to ensure project success while mentoring junior engineers and maintaining best practice...

3 days ago

  •   8 - 10 years exp.  •   Business Services

$180K - $200K *

Lead water infrastructure strategies, ensuring efficient design and compliance across data center projects. Collaborate with teams to secure agreements and manage risks, enhancing sustainability and c...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $150K *

Deliver exceptional emergency veterinary care while collaborating with a dedicated team. Play a key role in patient management, utilizing advanced technology and fostering client relationships in a fa...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Empower our engineering teams by leading technical recruitment efforts. Dive deep into candidate sourcing, build strong pipelines, and enhance the hiring process while ensuring a positive candidate ex...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$81K - $87K *

Transform genome editing research by leading innovative projects in molecular biology and bioinformatics. Collaborate with diverse teams to develop protocols and analytical strategies that enhance cro...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$130K - $160K *

Transform program execution by coordinating large-scale data center initiatives, ensuring alignment across stakeholders, managing risks, and driving milestones to successful completion while fostering...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$90K - $130K *

Join a team that's driving large-scale infrastructure projects. As a Project Manager, you'll lead initiatives from kickoff to closeout, ensuring alignment with program objectives and stakeholder expec...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Join a collaborative team delivering safe anesthesia care across diverse surgical specialties. This role offers a dynamic environment with opportunities for professional growth and leadership support...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.