Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,632
Nurse Anesthetist (CRNA) F/T - Duke University Hospital - Flexible Shifts
$170K - $200K *
Join a dynamic team providing anesthesia care in a Level 1 trauma center. You'll administer anesthetics, monitor patient status, and guide nurse anesthetists while ensuring optimal patient safety and...
Reposted 3 days ago
$350K - $400K *
Optimize enterprise sales growth by leading a high-performing team, refining strategies, and driving revenue. Collaborate across departments to enhance processes and ensure long-term success in a dyna...
3 days ago
Nurse Practitioner/Physician Assistant - Duke Neurosurgery FUNCTIONAL
$95K - $115K *
Join a team that's dedicated to advancing neurosurgical patient care through comprehensive assessments, procedures, and collaboration with physicians. This role emphasizes teamwork, flexibility, and a...
Reposted 3 days ago
Director, Labor Relations - Duke University Health System
$120K - $145K *
Join a team that's redefining labor relations in healthcare. Lead strategic initiatives, oversee compliance, and foster positive employee relations while managing a dedicated team. Collaborate with st...
3 days ago
Pediatric Ambulatory Clinical Pharmacist - Oncology Services
$110K - $130K *
Advance pediatric oncology and gene therapy by providing expert clinical pharmacy services, ensuring safe medication use, and collaborating with healthcare teams to enhance patient care and outcomes i...
Reposted 3 days ago
OR Service Line Coordinator (Neuro, Ortho, Peds) -Duke University Hospital
$80K - $95K *
Pioneer initiatives in operating room coordination, overseeing nurse and surgical team activities, managing schedules, and ensuring compliance with standards while supporting continuous education and...
Reposted 3 days ago
Physician Assistant/Nurse Practitioner - Duke Children's Health Center Nephrology
$95K - $115K *
Join our team as an Advanced Practice Provider, collaborating with physicians to deliver exceptional patient care in pediatric nephrology. Engage in diagnostic procedures, coordinate multidisciplinary...
3 days ago
Nurse Manager, AC - Spine Services Clinic
$85K - $100K *
Reimagine patient care in an ambulatory setting by providing exceptional leadership and operational guidance. Drive quality improvement and compliance while fostering a cohesive team environment to en...
Reposted 3 days ago
Marketing Manager- Duke Health Lake Norman
$80K - $95K *
Lead the charge in developing and executing strategic marketing plans that enhance brand awareness, drive patient acquisition, and support growth initiatives across the Lake Norman region, collaborati...
Reposted 3 days ago
Registered Nurse Leader - Blood Cancer Treatment Room Durham, NC
$80K - $95K *
Drive advanced nursing care by leading teams, enhancing patient education, and ensuring compliance with standards. Collaborate across disciplines to improve quality and mentor staff, fostering profess...
Reposted 3 days ago
Clinical Research Coordinator, Sr
$70K - $112K *
Unlock your potential by leading complex clinical research studies, providing regulatory expertise and operational support across multiple teams, ensuring compliance and excellence from startup throug...
Reposted 3 days ago
Nurse Practitioner/Physician Assistant - Duke GI Clinics of Cary & Brier Creek
$95K - $115K *
Elevate patient care by collaborating with physicians to evaluate, diagnose, and treat GI disorders. This role includes performing procedures, managing patient cases, and enhancing clinic operations a...
Reposted 3 days ago
$184K - $403K *
Lead the charge in shaping enterprise financial planning, guiding strategic decisions through insightful analyses and robust forecasting. Manage a high-performing team while driving accountability and...
3 days ago
SENIOR VICE PRESIDENT, STRATEGIC ALLIANCE - BUSINESS AND INDUSTRY SUPER SECTOR
$180K - $220K *
Champion retention and growth across our Super Sector portfolio by leading the Strategic Alliance Group. Influence strategies, enhance client partnerships, and execute operational excellence while dev...
Reposted 3 days ago
SENIOR VICE PRESIDENT, DATA CENTER STRATEGY
$208K - $250K *
Champion the growth and strategy of our Data Center vertical, leading a high-performing organization across diverse functions to deliver exceptional service in mission-critical environments and drive...
Reposted 3 days ago
Management Engineer - Acute Care Analytics and Improvement
$88K - $105K *
Unlock your potential by driving advanced analytics and performance improvement initiatives to enhance clinical operations and patient safety across community hospitals within a leading health system...
Reposted 3 days ago
DIRECTOR OF EVS, MORGANTON, NC
$85K - $95K *
Lead the charge in transforming operational efficiency within housekeeping. You'll oversee financial planning, manage department budgets, and liaise with administration to drive excellence in standard...
Reposted 3 days ago
Vice President, Benefits Strategy
$150K - $180K *
Lead the charge in designing innovative employee benefit plans that enhance workforce engagement and align with strategic goals. Collaborate across teams to ensure competitive, compliant, and cost-eff...
Reposted 3 days ago
$155K - $217K *
Join a dynamic team to negotiate and close high-profile commercial agreements, supporting various business units while driving growth in a leading SaaS company. Collaborate closely with sales and prod...
3 days ago
Project Manager AFM - Tulsa, OK
$95K - $115K *
Manage project lifecycles from order to delivery, ensuring quality, budget, and customer satisfaction. Collaborate across teams to drive communication and resolve escalations while championing continu...
Reposted 3 days ago
$150K - $160K *
Develop and execute strategies for deployment options across cloud and self-hosted setups, ensuring compliance and security. Collaborate with cross-functional teams to enhance product offerings and dr...
3 days ago
Account Director Senior Large Enterprise Forward Deployed
$132K - $177K *
Drive growth by managing large enterprise accounts, translating business priorities into measurable outcomes. Shape strategies, engage stakeholders, and lead complex sales cycles to enhance technology...
3 days ago
Account Director Senior Large Enterprise Forward Deployed
$126K - $185K *
Transform enterprise engagement by driving technology adoption and growth. Lead strategic initiatives across large accounts, leveraging deep market insights to deliver measurable outcomes and foster e...
3 days ago
Lead Business Systems Analyst (Charlotte, NC (Hybrid) or Remote)
$105K - $120K *
Join a team that's driving digital transformation by leading system analysis efforts. Collaborate with cross-functional teams to refine processes and deliver impactful solutions, ensuring alignment wi...
Reposted 3 days ago
Account Director Senior Large Enterprise Forward Deployed
$126K - $185K *
Shape technology adoption and growth by driving strategic initiatives across large enterprise accounts, translating business priorities into measurable outcomes through consultative engagement and exp...
3 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.