Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$214K - $268K *

Shape the strategy and outcomes for compliance and platform products, leading a team of product managers and domain experts. Drive innovation and customer engagement while ensuring enterprise-scale de...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$110K - $120K *

Empower your career by leading business analysis and configuration efforts. Collaborate with stakeholders to translate objectives into actionable requirements, ensuring successful project delivery and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $145K *

Join a team that's shaping the future of digital acquisition by owning the technical direction for our Growth area. You'll design APIs, mentor engineers, and collaborate across teams to enhance user e...

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$120K - $145K *

Lead the Sales Enablement team to drive impactful initiatives, collaborating with cross-functional leaders to enhance sales effectiveness in a fast-paced AI environment. Balance priorities and deliver...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Join a team that's dedicated to delivering top-notch field services for Pulp & Energy Solutions. You'll engage in hands-on maintenance, troubleshooting, and customer relations while traveling extensiv...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a dynamic team as a Research Scientist, leading innovative qualitative studies in clinical trials. Oversee project delivery, mentor junior staff, and drive scientific excellence while fostering c...

North Carolina, USRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Empower customer satisfaction by managing service operations, ensuring prompt and professional assistance while building lasting relationships and optimizing workflow in a dynamic automotive environme...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$69K - $95K *

Engage with stakeholders to prioritize and refine product backlogs, ensuring clarity and efficiency in development. Collaborate with cross-functional teams to drive innovative solutions and enhance us...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$290K - $342K *

Drive global partner and channel strategy, enhancing relationships and expanding market reach. Lead a high-performing team to innovate and execute programs that boost cross-sell opportunities and esta...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Information Technology

$170K - $234K *

Join a team that's redefining AI systems by leading the design and delivery of innovative ML solutions. Drive architectural decisions, mentor engineers, and shape AI strategy while ensuring reliabilit...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$81K - $87K *

Drive innovative genome editing research by leading molecular biology initiatives, developing protocols, and collaborating with diverse teams to enhance crop species and trait advancements in a dynami...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $176K *

Shape the future of AI-driven products by leading the development and market launch of innovative solutions. Collaborate with teams to enhance customer experiences and drive product success through st...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$124K - $160K *

Optimize vendor management and outsourcing strategies across R&D, focusing on Clinical Development. Collaborate with cross-functional teams to enhance performance, financial oversight, and risk manage...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $110K *

Advance your career by providing essential healthcare services in a rural community. Engage in occupational medicine evaluations, manage work-related injuries, and collaborate with employers to enhanc...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $142K *

Deliver high-quality software solutions by designing and developing scalable applications. Collaborate across teams to enhance customer experiences using modern technologies and best practices in a dy...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $190K *

Unlock potential by leading a dynamic SALT practice, delivering expert sales tax consulting services, mentoring staff, and driving business development while navigating complex tax challenges for dive...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$115K - $130K *

Reimagine tax management by joining a dynamic team focused on high-net-worth clients. Collaborate with financial advisors to deliver exceptional service, tackle complex tax issues, and thrive in a fas...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $176K *

Lead a pharmacy team to deliver exceptional patient care, ensuring compliance and operational excellence while fostering a culture of safety and empowerment. Drive performance through coaching, onboar...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate user experiences by leading UX design for innovative sleep health products. Collaborate with cross-functional teams to define and shape features that enhance adult sleep, driving impactful des...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$75K - $90K *

Join a team that's dedicated to enhancing customer success by managing relationships, driving revenue growth, and ensuring exceptional service for K-12 education clients. Collaborate across department...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$130K - $145K *

Lead the design and optimization of manufacturing processes, ensuring compliance and operational excellence. Collaborate across teams to drive continuous improvement and support the startup of a state...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$76K - $143K *

Join a team that's dedicated to enhancing laboratory operations and patient care. Lead staff, manage budgets, and ensure compliance while fostering a culture of safety and quality. Your expertise will...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$57K - $107K *

Contribute to laboratory excellence by performing tests, maintaining equipment, and supporting staff education. Ensure compliance with safety regulations while enhancing workflow and participating in...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $158K *

Join a team that's dedicated to solving complex HVAC and power generation challenges. Leverage your engineering expertise to design tailored solutions, collaborate with customers, and ensure successfu...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $166K *

Optimize site contract management by reviewing, drafting, and negotiating various legal agreements. Collaborate with clinical teams to ensure timely deliverables and serve as a subject matter expert i...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.