Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$170K - $190K *

Transform the future of enterprise deployment by leading SAP S/4HANA initiatives across multiple regions. Drive strategic alignment, ensure operational readiness, and deliver measurable outcomes while...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Elevate the standard of emergency veterinary care by providing compassionate, high-quality medicine in a supportive environment. Collaborate with a dedicated team while enjoying a flexible schedule an...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $187K *

Elevate client engagement by leading post-payment integrity implementations, ensuring seamless communication and alignment across teams. Drive successful outcomes through expert knowledge and strategi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $150K *

Unlock potential by serving as a strategic partner to the President, managing priorities, communications, and operations in a fast-paced environment. Your role is crucial in ensuring efficiency and cl...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $145K *

Lead the charge in designing and evolving scalable cloud infrastructure, driving architectural strategy, and enhancing operational culture while collaborating with cross-functional teams to meet ambit...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $120K *

Lead the charge in providing comprehensive care management for dually-eligible enrollees, integrating health services and community resources to enhance health outcomes and quality of life through eff...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $240K *

Drive cross-domain visibility and coordination in a dynamic engineering environment. As the sole TPM, you'll ensure programs are on track, dependencies are mapped, and automation enhances efficiency a...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Explore a dynamic role focused on building relationships with enterprise brands, driving business growth through strategic partnerships, and leveraging AI technologies to optimize processes. Engage in...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Advance the administration of Defined Benefit and Retiree Medical plans, ensuring accurate valuations, benefit calculations, and compliance with regulations. Collaborate on special projects while leve...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$89K - $142K *

Transform pharmacy strategies and drive innovation to optimize care costs and enhance outcomes. Leverage your expertise to lead cross-functional initiatives, develop revenue-generating solutions, and...

North Carolina, USRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$102K - $175K *

Accelerate your career by partnering with stakeholders to identify digital solutions, develop actionable insights, and enhance operational efficiency in manufacturing. Drive innovation through data an...

4 days ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Elevate your career by leading tire development projects, utilizing advanced engineering principles to design, test, and analyze replacement and original equipment tires while collaborating with custo...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$93K - $285K *

Drive operational excellence as a Senior Project Lead, overseeing clinical trial delivery and collaborating with teams to bring innovative treatments to market efficiently while ensuring compliance wi...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $180K *

Empower customer success by owning post-sale experiences, driving onboarding, adoption, and renewals. Collaborate with cross-functional teams to ensure every user thrives, turning initial deployments...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Deliver exceptional customer experiences by fostering relationships, guiding onboarding, and ensuring success metrics are met. Play a key role in customer retention and expansion while advocating for...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead the transformation of revenue cycle operations, enhancing efficiency and compliance while driving financial performance. Collaborate with teams to optimize processes and achieve strategic goals i...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Join our dynamic Payments Growth team to build innovative backend services and APIs that empower Hosts to maximize their earnings and drive business growth. Collaborate across functions to deliver imp...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$150K - $180K *

Innovate data-driven strategies to enhance business decision-making and optimize reporting processes. Leverage expertise in BI, CRM Analytics, and Salesforce to deliver actionable insights and support...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $105K *

Collaborate with us to manage federal government contracts, ensuring compliance and effective execution throughout the contracting lifecycle. Support proposal development, contract administration, and...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Staffing

$107K - $145K *

Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$198K - $297K *

Champion utilization management by conducting patient reviews, collaborating with medical staff, and leading initiatives to enhance compliance and efficiency. Drive results through effective communica...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Unlock potential by driving loss forecasting and analytics within Consumer and Business Banking. Collaborate with partners to analyze complex data, derive insights, and support strategic decision-maki...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$157K - $196K *

Unlock potential by leading the design and implementation of enterprise AI systems, driving innovation across diverse use cases while mentoring delivery teams to ensure excellence and fostering respon...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Business Services

$135K - $160K *

Drive clinical data management excellence by leading strategies, ensuring data integrity, and collaborating across functions to support successful clinical trials and regulatory submissions in a dynam...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $90K *

Help us ensure payroll accuracy and compliance while driving process improvements. As a Payroll Administrator, you'll maintain systems, resolve payroll issues, and lead projects for organizational gro...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.