Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$230K - $345K *

Transform clinical trial management by leading early-phase oncology programs. Drive strategic vision, operational excellence, and cross-functional collaboration to ensure timely, budget-compliant exec...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Manage change initiatives and communication strategies for a large-scale supplier sourcing transformation, ensuring stakeholder engagement and seamless adoption of new labor sourcing processes across...

3 days ago

  •   Less than 5 years exp.  •   Staffing

$80K - $95K *

Transform your career by leading mechanical construction projects, ensuring client satisfaction, managing schedules, and optimizing costs while collaborating with diverse teams and stakeholders. Your...

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$90K - $140K *

Lead the charge in managing complex EV Infrastructure projects, ensuring successful delivery within budget and deadlines while mentoring junior staff and collaborating with stakeholders to achieve hig...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$138K - $196K *

Elevate your career by leading NPI project management across diverse teams, ensuring alignment and accountability while driving operational efficiency and risk resolution in a dynamic environment...

3 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$80K - $100K *

Unlock your potential by contributing to enterprise EDI and integration projects. Collaborate with experienced engineers to design, implement, and optimize solutions, enhancing customer satisfaction a...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Drive your career forward by managing strategic enterprise accounts, fostering relationships, and identifying growth opportunities. Leverage your sales expertise to navigate complex cycles and collabo...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $155K *

Join a dynamic team to architect and deliver a cloud-native maintenance planning tool, driving modernization efforts and collaborating with diverse stakeholders to ensure seamless project execution an...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$300K - $350K *

Lead the transformation of financial institutions by driving client growth, delivering consulting excellence, and shaping the future of our retail banking and payments practice. Collaborate with C-sui...

3 days ago

  •   11 - 15 years exp.  •   Energy & Utilities

$62K - $107K *

Unlock potential by supporting financial operations through expert budgeting, analysis, and reporting. Collaborate with diverse stakeholders to ensure fiscal health and effective management within dep...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Optimize strategic leadership and operational excellence for CNS tumor programs, driving financial stewardship, program development, and collaborative partnerships across clinical, research, and acade...

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead cross-functional project execution in Medication Contracting, translating strategic priorities into actionable plans. Drive improvements, manage risks, and enhance collaboration across teams to e...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead field supervision and project coordination for ground-up commercial projects, ensuring timely delivery, budget adherence, and safety compliance while managing subcontractors and fostering stakeho...

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Lead the charge in overseeing construction projects, ensuring safety, quality, and efficiency. Direct trades and subcontractors while fostering team development and maintaining strong stakeholder rela...

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$85K - $90K *

Join a team that's committed to financial integrity and compliance. In this impactful role, you'll enhance risk management practices, collaborate across functions, and drive improvements that protect...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$180K - $200K *

Join a dynamic team to drive AI solutions in wealth management. Collaborate with executives to design tailored solutions, ensuring seamless integration and customer satisfaction while fostering innova...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $110K *

Partner with us to enhance distribution strategy, manage relationships, and drive process improvements. Lead annual planning, analyze performance, and seize growth opportunities while collaborating ac...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$240K - $288K *

Empower your career by delivering exceptional primary care in a supportive, team-based environment. Collaborate with dedicated professionals to enhance patient outcomes and innovate healthcare deliver...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $108K *

Champion high-impact strategic initiatives, collaborating with executives to drive alignment and measurable results across the organization while navigating complexity and change...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$100K - $120K *

Join a dynamic team to lead a global transition to D365 F&O, enhancing finance operations through process improvements and automation. Collaborate across departments to streamline complex business pro...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$160K - $225K *

Join us to build and lead our accounting function from the ground up, overseeing outsourced operations, establishing internal controls, and preparing for our first audit while driving system implement...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $224K *

Advance patient outcomes by leveraging your expertise in CNS as a Medical Science Liaison. Collaborate with healthcare providers and stakeholders to deliver evidence-based insights and drive strategic...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform patient care by providing expert pharmaceutical services, counseling, and immunizations. Collaborate with pharmacy staff to enhance customer experience and ensure compliance with regulations...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$90K - $110K *

Lead the charge in delivering innovative managed services solutions by partnering with sales teams to assess client needs, design scalable architectures, and ensure seamless transitions, driving long...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $120K *

Optimize customer connections by driving high-volume outreach and qualifying leads as a Bilingual Hybrid Development Representative. This role serves as a launchpad for aspiring Account Executives, fo...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.