Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,632

Sort By: Relevance

$95K - $115K *

Grow your career by driving revenue growth in the acute care market through new customer acquisition and account expansion. Manage the full sales lifecycle while collaborating with internal teams to d...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$228K - $342K *

Advance the future of R&D governance and portfolio management by leading strategic decision-making processes, optimizing operational efficiency, and ensuring seamless progression of therapeutic assets...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$76K - $93K *

Accelerate progress at customer success by building strong relationships, driving product adoption, and ensuring customer satisfaction. Collaborate cross-functionally to resolve issues and enhance cus...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$120K - $145K *

Accelerate enterprise initiatives by leading complex projects across teams, driving strategic execution, and enhancing operational excellence while partnering with stakeholders to deliver impactful so...

Charlotte, NCRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$105K - $120K *

Engage with public health labs to enhance customer satisfaction and drive sales. Collaborate with cross-functional teams to execute market strategies and foster relationships with key opinion leaders...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in shaping HR strategies that enhance recruitment, employee relations, and compliance. Collaborate with leadership to drive initiatives that support organizational goals in a dynamic...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Pioneer large-scale enterprise initiatives, leading cross-functional teams and driving strategic project execution while enhancing operational excellence and governance frameworks across the organizat...

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Lead your career with strategic oversight of multiple construction projects, driving profitability and client satisfaction. Mentor diverse teams while ensuring operational excellence and adherence to...

Yesterday

  •   11 - 15 years exp.  •   Real Estate & Construction

$95K - $115K *

Unlock your potential by driving innovation and revenue growth through strategic partnerships. Recruit and manage Value-Added Resellers to expand market presence and achieve ambitious sales targets in...

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $130K *

Lead the charge in enhancing employee IT experiences by managing service delivery, optimizing ITSM platforms, and driving automation initiatives. Collaborate across departments to ensure seamless tech...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Unlock the potential of high-voltage substation projects by overseeing design, development of control specifications, and relay settings while ensuring technical support and project coordination for s...

Reposted yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Drive quality assurance for innovative conversational AI solutions, ensuring reliability and accuracy across voice applications and customer engagement platforms. Collaborate with cross-functional tea...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Elevate your career by designing and optimizing EpicCare Ambulatory workflows. Collaborate with clinicians to enhance EHR functionality, troubleshoot issues, and ensure seamless operations across heal...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$103K - $208K *

Unlock potential by driving customer success and retention through strategic engagement and tailored solutions in a dynamic, collaborative environment focused on maximizing the value of enterprise clo...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$74K - $125K *

Transform cloud financial management by developing actionable insights and optimizing costs. Collaborate with technical teams to enhance efficiency and transparency in cloud utilization, ensuring stra...

Yesterday

  •   5 - 7 years exp.  •   Business Services

$107K - $204K *

Grow your career with a dynamic team leading SAP system administration, overseeing installations, upgrades, and performance tuning while collaborating with global peers to enhance aerospace solutions...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$132K - $251K *

Lead the charge in optimizing SAP systems, ensuring seamless installations and upgrades while enhancing performance and compliance. Collaborate with cross-functional teams to deliver innovative soluti...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Transform pediatric and neonatal clinical services through strategic leadership, operational excellence, and collaborative partnerships, ensuring high-quality patient care and workforce engagement in...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$99K - $120K *

Join a team that's redefining innovation in software engineering for critical facilities. You'll design and deliver cutting-edge applications and data solutions, driving projects from concept to deplo...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Technical Services

$113K - $125K *

Drive product strategy and outcomes in a senior role, focusing on educational equity and data-driven impact. Collaborate with cross-functional teams to shape product direction, prioritize initiatives...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Lead the charge in aerodynamic development, enhancing vehicle performance through innovative design, simulation, and testing. Collaborate across teams to translate aerodynamic insights into actionable...

Yesterday

  •   Less than 5 years exp.  •   Hospitality & Recreation

$95K - $115K *

Lead the charge in optimizing operational activities within the DHMS program, ensuring compliance and driving continuous improvement. Collaborate with stakeholders to implement effective strategies an...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$90K - $105K *

Elevate patient care by providing comprehensive services in a fast-paced urgent care setting. Lead a dedicated team while utilizing your full scope of practice to treat diverse patient populations and...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $258K *

Join a dynamic team driving Master Data Management strategies to enhance data governance and operational efficiency across global orthopedic initiatives. Lead cross-functional collaboration to ensure...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$102K - $157K *

Lead the charge in driving growth for Edge AI and IoT solutions, engaging both OT and IT stakeholders to secure new business and partnerships. Shape product roadmaps and deliver innovative solutions t...

Morrisville, NCRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.