Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,632

Sort By: Relevance

$77K - $144K *

Oversee the onboarding program and training processes, ensuring compliance and efficiency. Collaborate with stakeholders to enhance LMS functionality and support continuous improvement initiatives whi...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Champion patient recovery by delivering individualized, evidence-based physical therapy. Collaborate with a dedicated team to enhance mobility and improve lives, while fostering professional growth an...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$98K - $115K *

Join a team that's dedicated to delivering innovative payment solutions while leading audit engagements. As an Audit Project Manager, you'll supervise staff, ensure quality work, and collaborate acros...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$142K - $202K *

Unlock commercial potential by executing transformation workstreams, collaborating with cross-functional teams, and delivering strategic insights to drive measurable results in a healthcare-focused en...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Elevate AI experiences from concept to value by collaborating with engineering and design teams. Drive strategy, build prototypes, and make data-driven decisions to enhance user engagement and product...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Help us shape the future of federal security architecture by developing integrated designs and compliance strategies that protect sensitive information while ensuring reliable business operations acro...

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $200K *

Transform client relationships by driving business growth, securing profitable projects, and leveraging market access expertise. Lead teams to exceed expectations while identifying industry trends and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$165K - $220K *

Join a team that's redefining avionics systems engineering by translating customer needs into innovative architectures and requirements. Collaborate across domains to deliver high-quality solutions in...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$66K - $105K *

Join a team that's dedicated to delivering exceptional patient care through comprehensive assessments, individualized care plans, and effective collaboration with healthcare professionals to enhance p...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Drive your career with a strategic sales leadership role focused on enterprise growth in healthcare. Lead complex business development efforts, build executive relationships, and shape solutions that...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$130K - $155K *

Lead the AI/ML product strategy across multiple business units, driving integration and data-centric solutions that enhance customer value and revenue growth through innovative workflows and collabora...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Lead operational excellence in biopharmaceutical manufacturing, overseeing GMP processes, technology transfers, and clinical supply. Drive strategic initiatives, manage CDMO relationships, and build a...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in civil engineering for transmission and substation projects. Oversee site work, ensure compliance, and mentor engineers while collaborating with multidisciplinary teams to deliver hi...

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$108K - $130K *

Elevate your career by leading civil site projects for transmission and substations. Drive engineering excellence, manage site compliance, and collaborate with multidisciplinary teams to deliver innov...

Charlotte, NCRemote

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$106K - $146K *

Shape the future of our operations by leading a dynamic team to optimize Quote-to-Cash strategies, enhance analytics, and design streamlined workflows, all while collaborating across functions to driv...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$280K - $350K *

Unlock potential by leading a high-performing Enterprise sales team to drive revenue growth, mentor talent, and align strategies across departments, ensuring success in complex B2B SaaS solutions for...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in driving customer success for mid-market accounts, ensuring adoption and renewals while identifying growth opportunities. Collaborate cross-functionally to enhance customer experienc...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$68K - $115K *

Grow client relationships and drive sales in a remote field role, focusing on the Mid-Atlantic market. Engage with clients to understand their needs, resolve concerns, and expand market awareness whil...

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$114K - $117K *

Champion intelligence operations by overseeing collection management across multiple disciplines. Collaborate with national and tactical partners to prioritize customer requirements and enhance operat...

Yesterday

  •   8 - 10 years exp.  •   Business Services

$114K - $117K *

Join a dynamic team to oversee and enhance multi-discipline intelligence collection and production management, ensuring effective collaboration across national and tactical levels to meet diverse oper...

Yesterday

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Champion the evolution of organic search strategies across enterprise software brands. Lead initiatives in technical SEO, content optimization, and AI-driven search, driving visibility and revenue whi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $246K *

Pioneer innovative portfolio strategies for Manufacturing and Transportation solutions. Lead a dynamic team, drive product innovation, and collaborate across global functions to enhance offerings and...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$217K - $264K *

Lead and optimize the engineering team to enhance customer onboarding and lifecycle management, ensuring robust risk management and compliance across products while fostering a high-performing, inclus...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $140K *

Join a dynamic team to drive business growth by identifying and cultivating strategic partnerships. Leverage market insights to develop tailored solutions that meet mission needs and enhance client re...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead the strategic growth of technical integration services, overseeing specialized consultants and ensuring seamless, high-quality delivery of complex integrations while shaping the technical service...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.